-
1
-
-
0030730113
-
An update on primary drug therapies for Alzheimer disease
-
KNOPMAN DS, MORRIS JC: An update on primary drug therapies for Alzheimer's disease. Arch. Neurol. (1997) 54:1406-1409. (Pubitemid 27469357)
-
(1997)
Archives of Neurology
, vol.54
, Issue.11
, pp. 1406-1409
-
-
Knopman, D.S.1
Morris, J.C.2
-
2
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
SELKOE DJ: The molecular pathology of Alzheimer's disease. Neuron (1991) 6:487-498.
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
4
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
DOI 10.1038/325733a0
-
KANG J, LEMAIRE HG, UNTERBECK A et al.: The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature (1987) 325:733-736. (Pubitemid 17054046)
-
(1987)
Nature
, vol.325
, Issue.6106
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.-G.2
Unterbeck, A.3
-
5
-
-
0027184611
-
Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease
-
DOI 10.1006/abbi.1993.1112
-
MILLER DL, PAPAYANNOPOULOS IA, STYLES J et al.: Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease. Arch. Biochem. Biophys. (1993) 301:41-52. (Pubitemid 23227174)
-
(1993)
Archives of Biochemistry and Biophysics
, vol.301
, Issue.1
, pp. 41-52
-
-
Miller, D.L.1
Papayannopoulos, I.A.2
Styles, J.3
Bobin, S.A.4
Lin, Y.Y.5
Biemann, K.6
Iqbal, K.7
-
6
-
-
0028267440
-
Normal and abnormal biology of the β-amyloid precursor protein
-
SELKOE DJ: Normal and abnormal biology of the b-amyloid precursor protein. Ann. Rev. Neurosci. (1994) 17:489-517. (Pubitemid 24117040)
-
(1994)
Annual Review of Neuroscience
, vol.17
, pp. 489-517
-
-
Selkoe, D.J.1
-
7
-
-
0025971426
-
Apolipoprotein e immunoreactivity in cerebral deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease
-
NAMBA Y, TOMONAGA M, KAWASAKI H, OTOMO E, IKEDA K: Apolipoprotein E immunoreactivity in cerebral deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res. (1991) 541:163-166.
-
(1991)
Brain Res
, vol.541
, pp. 163-166
-
-
Namba, Y.1
Tomonaga, M.2
Kawasaki, H.3
Otomo, E.4
Ikeda, K.5
-
8
-
-
0023838532
-
1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease
-
DOI 10.1016/0092-8674(88)90462-X
-
ABRAHAM CR, SELKOE DJ, POTTER H: Immunochemical identification of the serine protease inhibitor, a1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell (1988) 52:487-501. (Pubitemid 18067514)
-
(1988)
Cell
, vol.52
, Issue.4
, pp. 487-501
-
-
Abraham, C.R.1
Selkoe, D.J.2
Potter, H.3
-
9
-
-
0023899417
-
Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis
-
CORIA F, CASTANO E, LARRONDO-LILLO M et al.: Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis. Lab. Invest. (1988) 58:454-458.
-
(1988)
Lab. Invest
, vol.58
, pp. 454-458
-
-
Coria, F.1
Castano, E.2
Larrondo-Lillo, M.3
-
10
-
-
0001360461
-
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
-
GRIFFIN WST, STANLEY LC, LING C et al.: Brain interleukin-1 and the S-100 immunoreactivity are elevated inDownsydrome and Alzheimer's disease. Proc. Natl. Acad. Sci. USA (1989) 86:7611-7615. (Pubitemid 19254506)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.19
, pp. 7611-7615
-
-
Griffin, W.S.T.1
Stanley, L.C.2
Ling, C.3
White, L.4
MacLeod, V.5
Perrot, L.J.6
White III, C.L.7
Araoz, C.8
-
11
-
-
0025549815
-
Induction of basic fibroblast growth factor in Alzheimer's disease pathology
-
GOMEZ-PINILLA F, CUMMINGS BJ, COTMAN CW: Induction of basic fibroblast growth factor in Alzheimer's disease pathology. Neuroreport (1990) 1:211-214.
-
(1990)
Neuroreport
, vol.1
, pp. 211-214
-
-
Gomez-Pinilla, F.1
Cummings, B.J.2
Cotman, C.W.3
-
12
-
-
0025763298
-
Interleukin-6 and alpha-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices
-
BAUER J, STRAUSS S, SCHREITER-GASSER U et al.: Interleukin-6 and alpha-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices. FEBS Lett. (1991) 285:111-114.
-
(1991)
FEBS Lett
, vol.285
, pp. 111-114
-
-
Bauer, J.1
Strauss, S.2
Schreiter-Gasser, U.3
-
13
-
-
0027263617
-
2 macroglobulin receptor in Alzheimer and control postmortem human brain
-
TOOYAMA I, KAWAMATA T, AKIYAMA H et al: Immunohistochemical study of a a2-macroglobulin receptor in Alzheimer and control postmortem human brain. Mol. Chem. Neuropathol. (1993) 18:153-160. (Pubitemid 23129000)
-
(1993)
Molecular and Chemical Neuropathology
, vol.18
, Issue.1-2
, pp. 153-160
-
-
Tooyama, I.1
Kawamata, T.2
Akiyama, H.3
Moestrup, S.K.4
Gliemann, J.5
McGeer, P.L.6
-
14
-
-
0024273721
-
The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease
-
SNOW AD, MAR H, HOCHLIN D et al.: The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease. Am. J. Pathol. (1988) 133:456-463. (Pubitemid 19020577)
-
(1988)
American Journal of Pathology
, vol.133
, Issue.3
, pp. 456-463
-
-
Snow, A.D.1
Mar, H.2
Nochlin, D.3
Kimata, K.4
Kato, M.5
Suzuki, S.6
Hassell, J.7
Wight, T.N.8
-
15
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
MCGEER PL, SCHULZER M, MCGEER EG: Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology (1996) 47:425-432. (Pubitemid 26324038)
-
(1996)
Neurology
, vol.47
, Issue.2
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
16
-
-
0024387388
-
Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses
-
DOI 10.1016/0197-4580(89)90108-5
-
SNOW AD, WIGHT TN: Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses. Neurobiol. Aging (1989) 10:481-497. (Pubitemid 19245453)
-
(1989)
Neurobiology of Aging
, vol.10
, Issue.5
, pp. 481-497
-
-
Snow, A.D.1
Wight, T.N.2
-
17
-
-
0032507975
-
Copper, iron and zinc in Alzheimer's disease senile plaques
-
DOI 10.1016/S0022-510X(98)00092-6, PII S0022510X98000926
-
LOVELL MA, ROBERTSON JD, TEESDALE WJ, CAMPBELL JL, MARKESBERY WR: Copper, iron and zinc in Alzheimer's disease senile plaques. J. Neurosci. Res. (1998) 158:47-52. (Pubitemid 28277534)
-
(1998)
Journal of the Neurological Sciences
, vol.158
, Issue.1
, pp. 47-52
-
-
Lovell, M.A.1
Robertson, J.D.2
Teesdale, W.J.3
Campbell, J.L.4
Markesbery, W.R.5
-
18
-
-
0024447098
-
Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease
-
JOACHIM CL, MORRIS JH, SELKOE DJ: Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease. Am. J. Pathol. (1989) 135:309-319. (Pubitemid 19240215)
-
(1989)
American Journal of Pathology
, vol.135
, Issue.2
, pp. 309-319
-
-
Joachim, C.L.1
Morris, J.H.2
Selkoe, D.J.3
-
19
-
-
0028331648
-
Senile plaques do not progressively accumulate with normal aging
-
MACKENZIE IRA: Senile plaques do not progressively accumulate with normal aging. Acta Neuropathol. (1994) 87:520-525.
-
(1994)
Acta Neuropathol
, vol.87
, pp. 520-525
-
-
MacKenzie, I.R.A.1
-
21
-
-
0027058857
-
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau
-
DRECHSEL DN, HYMAN AA, COBB MH, KIRSCHNER MW: Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol. Biol. Cell (1992) 3:1141-1154. (Pubitemid 23088964)
-
(1992)
Molecular Biology of the Cell
, vol.3
, Issue.10
, pp. 1141-1154
-
-
Drechsel, D.N.1
Hyman, A.A.2
Cobb, M.H.3
Kirschner, M.W.4
-
22
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein t (tau) in Alzheimer cytoskeletal pathology
-
GRUNDKE-IQBAL I, IQBAL K, TUNG Y et al.: Abnormal phosphorylation of the microtubule-associated protein t (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA (1986) 83:4913-4917.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.3
-
23
-
-
0027308924
-
396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
-
DOI 10.1016/0896-6273(93)90057-X
-
BRAMBLETT GT, GOEDERT M, JAKES R et al.: Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding. Neuron (1993) 10:1089-1099. (Pubitemid 23194399)
-
(1993)
Neuron
, vol.10
, Issue.6
, pp. 1089-1099
-
-
Bramblett, G.T.1
Goedert, M.2
Jakes, R.3
Merrick, S.E.4
Trojanowski, J.Q.5
Lee -, V.M.Y.6
-
24
-
-
79961049803
-
Tau protein and the neurofibrillary pathology of Alzheimer's disease
-
Wasco W, Tanzi RE (Eds.), Humana Press
-
GOEDERT M, TROJANOWSKI JQ, LEE VMY: Tau protein and the neurofibrillary pathology of Alzheimer's disease. In: Mechanisms of Dementia. Wasco W, Tanzi RE (Eds.), Humana Press (1997).
-
(1997)
Mechanisms of Dementia
-
-
Goedert, M.1
Trojanowski, J.Q.2
Lee, V.M.Y.3
-
25
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
BRAAK H, BRAAK E: Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berl.) (1991) 82:239-259.
-
(1991)
Acta Neuropathol. (Berl.)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
26
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
ARRIAGADA PV, GROWDON JH, HEDLEY-WHITE ET, HYMAN BT: Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology (1992) 42:631-639.
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.V.1
Growdon, J.H.2
Hedley-White, E.T.3
Hyman, B.T.4
-
27
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
GOATE A, CHARTIER-HARLIN M,MULLANMet al.: Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature (1991) 349:704-706. (Pubitemid 21912142)
-
(1991)
Nature
, vol.349
, Issue.6311
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fldani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
28
-
-
0025950987
-
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease
-
MURRELL J, FARLOW M, GHETTI B: A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science (1991) 254:97-98.
-
(1991)
Science
, vol.254
, pp. 97-98
-
-
Murrell, J.1
Farlow, M.2
Ghetti, B.3
-
29
-
-
0026075602
-
Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene
-
CHARTIER-HARLIN M, CRAWFORD F, HOULDEN H: Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene. Nature (1991) 353:844-846. (Pubitemid 21912637)
-
(1991)
Nature
, vol.353
, Issue.6347
, pp. 844-846
-
-
Chartier-Harlin, M.-C.1
Crawford, F.2
Houlden, H.3
Warren, A.4
Hughes, D.5
Fidani, L.6
Goate, A.7
Rossor, M.8
Roques, P.9
Hardy, J.10
Mullan, M.11
-
30
-
-
0026907151
-
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of b-amyloid
-
MULLAN M, CRAWFORD F, AXELMAN K et al.: A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of b-amyloid. Nature Genet. (1992) 1:345-347.
-
(1992)
Nature Genet
, vol.1
, pp. 345-347
-
-
Mullan, M.1
Crawford, F.2
Axelman, K.3
-
31
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
SHERRINGTON R, ROGAEV EI, LIANG Y et al.: Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature (1995) 375:754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
-
32
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
LEVY-LAHAD E, WASCO W, POORKAJ P et al.: Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science (1995) 269:973-977.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
-
33
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
CORDER EH, SAUNDERS AM, STRITTMATTER WJ et al.: Gene dose of apolipoprotein E Type 4 allele and the risk of Alzheimer's disease in late onset families. Science (1993) 261:921-923. (Pubitemid 23275809)
-
(1993)
Science
, vol.261
, Issue.5123
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
34
-
-
17344362232
-
Alpha-2 macroglobulin is genetically associated with Alzheimer disease
-
DOI 10.1038/1243
-
BLACKER D, WILCOX MA, LAIRD NM et al.: Alpha-2 macroglobulin is genetically associated with Alzheimer's disease. Nature Genet. (1998) 19:357-360. (Pubitemid 28357907)
-
(1998)
Nature Genetics
, vol.19
, Issue.4
, pp. 357-360
-
-
Blacker, D.1
Wilcox, M.A.2
Laird, N.M.3
Rodes, L.4
Horvath, S.M.5
Go, R.C.P.6
Perry, R.7
Watson Jr., B.8
Bassett, S.S.9
McInnis, M.G.10
Albert, M.S.11
Hyman, B.T.12
Tanzi, R.E.13
-
35
-
-
0026731852
-
Distribution of the a2-macroglobulin/low density lipoprotein receptor-related protein in human tissues
-
MOESTRUP SK, GLIEMANN J, PALLESEN G: Distribution of the a2-macroglobulin/low density lipoprotein receptor-related protein in human tissues. Cell Tissue Res. (1992) 269:375-382.
-
(1992)
Cell Tissue Res
, vol.269
, pp. 375-382
-
-
Moestrup, S.K.1
Gliemann, J.2
Pallesen, G.3
-
36
-
-
0028173897
-
Structures and functions of multi-ligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein
-
KRIEGER M, HERZ J: Structures and functions of multi-ligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein. Ann. Rev. Biochem. (1994) 63:601-637.
-
(1994)
Ann. Rev. Biochem
, vol.63
, pp. 601-637
-
-
Krieger, M.1
Herz, J.2
-
37
-
-
0040177065
-
Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins
-
KOWAL RC, HERZ J, GOLDSTEIN JL et al.: Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proc. Natl. Acad. Sci. USA (1989) 86:5810-5814. (Pubitemid 19217543)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.15
, pp. 5810-5814
-
-
Kowal, R.C.1
Herz, J.2
Goldstein, J.L.3
Esser, V.4
Brown, M.S.5
-
38
-
-
0030752288
-
Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease
-
KANG DE, SAITOH T, CHEN X et al.: Genetic association of the low density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease. Neurology (1997) 49:56-61. (Pubitemid 27328682)
-
(1997)
Neurology
, vol.49
, Issue.1
, pp. 56-61
-
-
Kang, D.E.1
Saitoh, T.2
Chen, X.3
Xia, Y.4
Masliah, E.5
Hansen, L.A.6
Thomas, R.G.7
Thal, L.J.8
Katzman, R.9
-
39
-
-
0006878659
-
Association between the low density lipoprotein receptor-related protein (LRP) and Alzheimer's disease
-
DOI 10.1016/S0304-3940(97)00304-2, PII S0304394097003042
-
WAVRANT-DEVRIEZE F, PEREZ-TUR J, LAMBERT JC et al.: Association between the low density lipoprotein receptor-related protein (LRP) and Alzheimer's disease. Neurosci. Lett. (1997) 227:68-70. (Pubitemid 27239542)
-
(1997)
Neuroscience Letters
, vol.227
, Issue.1
, pp. 68-70
-
-
Wavrant-Devrieze, F.1
Perez-Tur, J.2
Lambert, J.-C.3
Frigard, B.4
Pasquier, F.5
Delacourte, A.6
Amouyel, P.7
Hardy, J.8
Chartier-Harlin, M.-C.9
-
40
-
-
0029118873
-
Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease
-
OKUIZUMI K, ONODERA O, NAMBA Y et al.: Genetic association of the very low density lipoprotein (VLDL) receptor gene with sporadic Alzheimer's disease. Nature Genet. (1995) 11:207-209.
-
(1995)
Nature Genet
, vol.11
, pp. 207-209
-
-
Okuizumi, K.1
Onodera, O.2
Namba, Y.3
-
41
-
-
12644257598
-
Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease
-
DOI 10.1073/pnas.94.9.4526
-
DAVIS RE, MILLER S, HERRNSTADT C et al.: Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer's disease. Proc. Natl. Acad. Sci. USA (1997) 94:4526-4531. (Pubitemid 27194275)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.9
, pp. 4526-4531
-
-
Davis, R.E.1
Miller, S.2
Herrnstadt, C.3
Ghosh, S.S.4
Fahy, E.5
Shinobu, L.A.6
Galasko, D.7
Thal, L.J.8
Beal, M.F.9
Howell, N.10
Parker Jr., W.D.11
-
42
-
-
0030882168
-
Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease
-
CLATWORTHY AE, GOMEZ-ISLA T, REBECK GW, WALLACE RB, HYMAN BT: Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer's disease. Arch. Neurol. (1997) 54:1289-1292. (Pubitemid 27452245)
-
(1997)
Archives of Neurology
, vol.54
, Issue.10
, pp. 1289-1292
-
-
Clatworthy, A.E.1
Gomez-Isla, T.2
Rebeck, G.W.3
Wallace, R.B.4
Hyman, B.T.5
-
43
-
-
0030000181
-
No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians
-
DOI 10.1016/0304-3940(96)12630-6
-
PRITCHARD ML, SAUNDERS AM, GASKELL PC et al.: No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer's disease in American caucasians. Neurosci. Lett. (1996) 209:105-108. (Pubitemid 26157798)
-
(1996)
Neuroscience Letters
, vol.209
, Issue.2
, pp. 105-108
-
-
Pritchard, M.L.1
Saunders, A.M.2
Gaskell, P.C.3
Small, G.W.4
Conneally, P.M.5
Rosi, B.6
Yamaoka, L.H.7
Roses, A.D.8
Haines, J.L.9
Pericak-Vance, M.A.10
-
44
-
-
0032571142
-
Evidence that two reports of mtDNA cytochrome C oxidase 'mutations' in Alzheimer's disease are based on mDNA pseudogenes of recent evolutionary origin
-
DAVIS JN, PARKER WDJ: Evidence that two reports of mtDNA cytochrome C oxidase 'mutations' in Alzheimer's disease are based on mDNA pseudogenes of recent evolutionary origin. Biochem. Biophys. Res. Commun. (1998) 244:877-883.
-
(1998)
Biochem. Biophys. Res. Commun
, vol.244
, pp. 877-883
-
-
Davis, J.N.1
Parker, W.D.J.2
-
45
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia
-
DOI 10.1002/ana.410430617
-
POORKAJ P, BIRD TD, WIJSMAN E et al.: Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann. Neurol. (1998) 43:815-825. (Pubitemid 28280226)
-
(1998)
Annals of Neurology
, vol.43
, Issue.6
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
Anderson, L.6
Andreadis, A.7
Wiederholt, W.C.8
Raskind, M.9
Schellenberg, G.D.10
-
46
-
-
0032543684
-
Association of missense and 5¢-splice-site mutations in tau with the inherited dementia FTDP-17
-
HUTTON M, LENDON CL, RIZZU P et al.: Association of missense and 5¢-splice-site mutations in tau with the inherited dementia FTDP-17. Nature (1998) 393:702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
-
47
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
DOI 10.1073/pnas.95.13.7737
-
SPILLANTINI MG, MURRELL JR, GOEDERTMet al.: Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc. Natl. Acad. Sci. USA (1998) 95:7737-7741. (Pubitemid 28293323)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.13
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
48
-
-
0028322017
-
An increased percentage of long amyloid b protein secreted by familial amyloid b protein precursor (bAPP717) mutants
-
SUZUKI N, CHEUNG TT, CAI X et al.: An increased percentage of long amyloid b protein secreted by familial amyloid b protein precursor (bAPP717) mutants. Science (1994) 264:1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.3
-
49
-
-
79961095682
-
The molecular genetics of Alzheimer's disease
-
Martin JB (Ed.), Scientific American
-
TANZI RE: The molecular genetics of Alzheimer's disease. In: Scientific American: Molecular Neurology. Martin JB (Ed.), Scientific American (1998).
-
(1998)
Scientific American: Molecular Neurology
-
-
Tanzi, R.E.1
-
50
-
-
0029101491
-
Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease Type 3 gene
-
ROGAEV EI, SHERRINGTON R, ROGAEVA EA et al.: Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease Type 3 gene. Nature (1995) 376:775-778.
-
(1995)
Nature
, vol.376
, pp. 775-778
-
-
Rogaev, E.I.1
Sherrington, R.2
Rogaeva, E.A.3
-
51
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin I variants elevate aβ1- 42/1-40 ratio in vitro and in vivo
-
DOI 10.1016/S0896-6273(00)80230-5
-
BORCHELT DR,THINAKARA NG,ECKMAN Cet al.: Familial Alzheimer's disease-linked presenilin 1 variants elevate Ab1-42/1-40 ratio in vitro and in vivo. Neuron (1996) 17:1005-1013. (Pubitemid 26424026)
-
(1996)
Neuron
, vol.17
, Issue.5
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.-M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
52
-
-
16944365745
-
Enhanced production and oligomerization of the 42-residue amyloid β- protein by chinese hamster ovary cells stably expressing mutant presenilins
-
DOI 10.1074/jbc.272.12.7977
-
XIA W, ZHANG J, KHOLODENKO D et al.: Enhanced production and oligomerization of the 42-residue amyloid b-protein by Chinese hamster ovary cells stably expressing mutant presenilins. J. Biol. Chem. (1997) 272:7977-7982. (Pubitemid 27137361)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.12
, pp. 7977-7982
-
-
Xia, W.1
Zhang, J.2
Kholodenko, D.3
Citron, M.4
Podlisny, M.B.5
Teplow, D.B.6
Haass, C.7
Seubert, P.8
Koo, E.H.9
Selkoe, D.J.10
-
53
-
-
0031594142
-
Increased Aβ42(43) from cell lines expressing presenilin 1 mutations
-
DOI 10.1002/ana.410430217
-
MEHTAN D, REFOLO LM,ECKMAN Cet al.: IncreasedAb42(43) from cell lines expressing presenilin 1 mutations. Ann. Neurol. (1998) 43:256-258. (Pubitemid 28110129)
-
(1998)
Annals of Neurology
, vol.43
, Issue.2
, pp. 256-258
-
-
Mehta, N.D.1
Refolo, L.M.2
Eckman, C.3
Sanders, S.4
Yager, D.5
Perez-Tur, J.6
Younkin, S.7
Duff, K.8
Hardy, J.9
Hutton, M.10
-
54
-
-
12644258498
-
The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue
-
DOI 10.1073/pnas.94.5.2025
-
TOMITA T, MARUYAMA K, SAIDO TC et al.: The presenilin 2 mutation (N141I) linked to familial Alzheimer's disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue. Proc. Natl. Acad. Sci. USA (1997) 94:2025-2030. (Pubitemid 27113955)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.5
, pp. 2025-2030
-
-
Tomita, T.1
Maruyama, K.2
Saido, T.C.3
Kume, H.4
Shinozaki, K.5
Tokuhiro, S.6
Capell, A.7
Walter, J.8
Grunberg, J.9
Haass, C.10
Iwatsubo, T.11
Obata, K.12
-
55
-
-
9444276544
-
Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: Predominance of Abeta42(43)
-
MANN DM, IWATSUBO T, CAIRNS NJ et al.: Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43). Ann. Neurol. (1996) 40:149-156.
-
(1996)
Ann. Neurol
, vol.40
, pp. 149-156
-
-
Mann, D.M.1
Iwatsubo, T.2
Cairns, N.J.3
-
56
-
-
15144345926
-
A novel presenilin-1 mutation: Increased β-amyloid and neurofibrillary changes
-
DOI 10.1002/ana.410410618
-
GOMEZ-ISLA T, WASCO W, PETTINGELL WP et al.: A novel presenilin-1 mutation: increased beta-amyloid and neurofibrillary changes. Ann. Neurol. (1997) 41:809-813. (Pubitemid 27249187)
-
(1997)
Annals of Neurology
, vol.41
, Issue.6
, pp. 809-813
-
-
Gomez-Isla, T.1
Wasco, W.2
Pettingell, W.P.3
Gurubhagavatula, S.4
Schmidt, S.D.5
Jondro, P.D.6
McNamara, M.7
Rodes, L.A.8
DiBlasi, T.9
Growdon, W.B.10
Seubert, P.11
Schenk, D.12
Growdon, J.H.13
Hyman, B.T.14
Tanzi, R.E.15
-
57
-
-
16044365171
-
The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology
-
DOI 10.1038/nm1096-1146
-
LEMERE CA, LOPERA F, KOSIK KS et al.: The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology. Nature Med. (1996) 2:1146-1150. (Pubitemid 26338637)
-
(1996)
Nature Medicine
, vol.2
, Issue.10
, pp. 1146-1150
-
-
Lemere, C.A.1
Lopera, F.2
Kosik, K.S.3
Lendon, C.L.4
Ossa, J.5
Saido, T.C.6
Yamaguchi, H.7
Ruiz, A.8
Martinez, A.9
Madrigal, L.10
Hincapie, L.11
Arango, L.J.C.12
Anthony, D.C.13
Koo, E.H.14
Goate, A.M.15
Selkoe, D.J.16
Arango, V.J.C.17
-
58
-
-
0030667339
-
α-Secretase-derived product of β-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease
-
ANCOLIO K, MARAMBAUD P, DAUCH P, CHECLER F: a-Secretase-derived product of b-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alheimer's disease. J. Neurochem. (1997) 69:2494-2499. (Pubitemid 27495436)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.6
, pp. 2494-2499
-
-
Ancolio, K.1
Marambaud, P.2
Dauch, P.3
Checler, F.4
-
59
-
-
16044366039
-
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
-
DOI 10.1038/383710a0
-
DUFF K,ECKMAN C,ZEHR Cet al.: Increased amyloid-b42(43) in brains of mice expressing presenilin 1. Nature (1996) 383:710-713. (Pubitemid 26360645)
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
60
-
-
0027327267
-
Association of apolipoprotein E allele ε4 with late-onset familial and sporadic Alzheimer's disease
-
SAUNDERS AM, STRITTMATTER WJ, SCHMECHEL DE et al.: Association of apolipoprotein E allele e4 with late-onset familial and sporadic Alzheimer's disease. Neurology (1993) 43:1467-1472. (Pubitemid 23230526)
-
(1993)
Neurology
, vol.43
, Issue.8
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
St. George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-MacLachlan, D.R.9
Alberts, M.J.10
Hulette, C.11
Crain, B.12
Goldgaber, D.13
Roses, A.D.14
-
61
-
-
0024299370
-
Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
-
MAHLEY RW: Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science (1988) 240:622-628.
-
(1988)
Science
, vol.240
, pp. 622-628
-
-
Mahley, R.W.1
-
62
-
-
0028341794
-
Clinical application of apolipoprotein E genotyping to Alzheimer's disease [1]
-
DOI 10.1016/S0140-6736(94)92960-2
-
ROSES AD, STRITTMATTER WJ, PERICAK-VANCE M et al.: Clinical application of apolipoprotein E genotyping to Alzheimer's disease. Lancet (1994) 343:1564-1565. (Pubitemid 24180058)
-
(1994)
Lancet
, vol.343
, Issue.8912
, pp. 1564-1565
-
-
Roses, A.D.1
Strittmatter, W.J.2
Pericak-Vance, M.A.3
Corder, E.H.4
Saunders, A.M.5
Schmechel, D.E.6
-
63
-
-
17344374322
-
A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia
-
DOI 10.1038/ng0198-69
-
BULLIDO MJ, ARTIGA MJ, RECUEROMet al.:Apolymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia. Nature Genet. (1998) 18:69-71. (Pubitemid 28027883)
-
(1998)
Nature Genetics
, vol.18
, Issue.1
, pp. 69-71
-
-
Bullido, M.J.1
Artiga, M.J.2
Recuero, M.3
Sastre, I.4
Garcia, M.A.5
Aldudo, J.6
Lendon, C.7
Han, S.W.8
Morris, J.C.9
Frank, A.10
Vazquez, J.11
Goate, A.12
Valdivieso, F.13
-
64
-
-
0031911596
-
A new polymorphism in the APOE promoter associated with risk of developing Alzheimer's disease
-
DOI 10.1093/hmg/7.3.533
-
LAMBERT JC, PASQUIER F, COTTEL D et al.: A new polymorphism in the ApoE promoter associated with risk of developing Alzheimer's disease. Hum. Mol. Genet. (1998) 7:533-540. (Pubitemid 28120646)
-
(1998)
Human Molecular Genetics
, vol.7
, Issue.3
, pp. 533-540
-
-
Lambert, J.-C.1
Pasquier, F.2
Cottel, D.3
Frigard, B.4
Amouyel, P.5
Chartier-Harlin, M.-C.6
-
65
-
-
0027076834
-
2-Macroglobulin, a multifunctional binding protein with targeting characteristics
-
BORTH W: a2-Macroglobulin, a multifunctional binding protein with targeting characteristics. FASEB J. (1992) 6:3345-3353. (Pubitemid 23007099)
-
(1992)
FASEB Journal
, vol.6
, Issue.15
, pp. 3345-3353
-
-
Borth, W.1
-
66
-
-
0023109592
-
Amyloid β protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
TANZI RE, GUSELLA JF, WATKINS PC et al.: Amyloid b protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science (1987) 235:880-884. (Pubitemid 17019125)
-
(1987)
Science
, vol.235
, Issue.4791
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
-
68
-
-
0027500468
-
Differential regional and cellular distribution of β-amyloid precursor protein messenger RNAs containing and lacking the Kunitz protease inhibitor domain in the brain of human, rat and mouse
-
DOI 10.1016/0306-4522(93)90304-X
-
SOLA C, MENGOD G, PROBST A, PALACIOS JM: Differential regional and cellular distribution of b-amyloid precursor protein messenger RNAs containing and lacking the kunitz protease inhibitor domain in the brain of the human, rat and mouse. Neuroscience (1993) 53:267-295. (Pubitemid 23083327)
-
(1993)
Neuroscience
, vol.53
, Issue.1
, pp. 267-295
-
-
Sola, C.1
Mengod, G.2
Probst, A.3
Palacios, J.M.4
-
69
-
-
0023850791
-
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
-
DOI 10.1038/331528a0
-
TANZI RE,MCCLATCHEY AI, LAMPERTI ED et al.: Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature (1988) 331:528-530. (Pubitemid 18064376)
-
(1988)
Nature
, vol.331
, Issue.6156
, pp. 528-530
-
-
Tanzi, R.E.1
McClatchey, A.I.2
Lamperti, E.D.3
Villa-Komaroff, L.4
Gusella, J.F.5
Neve, R.L.6
-
70
-
-
0023870043
-
A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors
-
DOI 10.1038/331525a0
-
PONTE P, GONZALEZ-DEWHITT P, SCHILLING J: A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature (1988) 331:525-527. (Pubitemid 18064375)
-
(1988)
Nature
, vol.331
, Issue.6156
, pp. 525-527
-
-
Ponte, P.1
Gonzalez-DeWhitt, P.2
Schilling, J.3
Miller, J.4
Hsu, D.5
Greenberg, B.6
Davis, K.7
Wallace, W.8
Lieberburg, I.9
Fuller, F.10
Cordell, B.11
-
71
-
-
0025250145
-
NPXY, a sequence often found in cytoplasmic tails, is required for coated-pit mediated internalization of the low density lipoprotein receptor
-
CHEN W-J, GOLDSTEIN JL, BROWN MS: NPXY, a sequence often found in cytoplasmic tails, is required for coated-pit mediated internalization of the low density lipoprotein receptor. J. Biol. Chem. (1990) 265:3116-3123.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 3116-3123
-
-
Chen, W.-J.1
Goldstein, J.L.2
Brown, M.S.3
-
72
-
-
0028966092
-
Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain
-
LAI A, SISODIA SS, TROWBRIDGE IS: Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain. J. Biol. Chem. (1995) 270:3565-3573.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 3565-3573
-
-
Lai, A.1
Sisodia, S.S.2
Trowbridge, I.S.3
-
73
-
-
0024550204
-
Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein
-
DOI 10.1016/0092-8674(89)90177-3
-
WEIDEMAN NA, KONIG G, BUNKE Det al.: Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 protein. Cell (1989) 57:115-126. (Pubitemid 19098873)
-
(1989)
Cell
, vol.57
, Issue.1
, pp. 115-126
-
-
Weidemann, A.1
Konig, G.2
Bunke, D.3
Fischer, P.4
Salbaum, J.M.5
Masters, C.L.6
Beyreuther, K.7
-
74
-
-
0025295039
-
Cleavage of amyloid b peptide during constitutive processing of its precursor
-
ESCH FS, KEIM PS, BEATTIE EC et al.: Cleavage of amyloid b peptide during constitutive processing of its precursor. Science (1990) 248:1122-1124.
-
(1990)
Science
, vol.248
, pp. 1122-1124
-
-
Esch, F.S.1
Keim, P.S.2
Beattie, E.C.3
-
75
-
-
0026539090
-
Processing of the amyloid protein precursor to potentially amyloidogenic derivatives
-
GOLDE TE, ESTUS S,YOUNKIN LH,SELKOE DJ,YOUNKIN SG: Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. Science (1992) 255:728-730.
-
(1992)
Science
, vol.255
, pp. 728-730
-
-
Golde, T.E.1
Estus, S.2
Younkin, L.H.3
Selkoe, D.J.4
Younkin, S.G.5
-
76
-
-
0028210978
-
Characterization of a novel processing pathway for Alzheimer's amyloid β precursor protein
-
DOI 10.1016/0304-3940(94)90642-4
-
GHISO J, GARDELLA JE, LIEM L, GOREVIC PD, FRANGIONE B: Characterization of a novel processing pathway for Alzheimer's amyloid b precursor protein. Neurosci. Lett. (1994) 171:213-216. (Pubitemid 24142127)
-
(1994)
Neuroscience Letters
, vol.171
, Issue.1-2
, pp. 213-216
-
-
Ghiso, J.1
Gardella, J.E.2
Liem, L.3
Gorevic, P.D.4
Frangione, B.5
-
77
-
-
0026646605
-
Isolation and quantitation of soluble Alzheimer's b-peptide from biological fluids
-
SEUBERT P, VIGO-PELFREY C, ESCH FS: Isolation and quantitation of soluble Alzheimer's b-peptide from biological fluids. Nature (1992) 359:325-327.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.S.3
-
78
-
-
0026760261
-
Production of the Alzheimer amyloid b protein by normal proteolytic processing
-
SHOJI M, GOLDE T, GHISO J et al.: Production of the Alzheimer amyloid b protein by normal proteolytic processing. Science (1992) 258:126-129.
-
(1992)
Science
, vol.258
, pp. 126-129
-
-
Shoji, M.1
Golde, T.2
Ghiso, J.3
-
79
-
-
0027535111
-
β-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms
-
HAASS C, HUNG AY, SCHLOSSMACHER MG, TEPLOW DB, SELKOE DJ: b-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms. J. Biol. Chem. (1993) 268:3021-3024. (Pubitemid 23070917)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.5
, pp. 3021-3024
-
-
Haass, C.1
Hung, A.Y.2
Schlossmacher, M.G.3
Teplow, D.B.4
Selkoe, D.J.5
-
80
-
-
0026646604
-
Amyloid b-peptide is produced by cultured cells during normal metabolism
-
HAASS C, SCHLOSSMACHER MG, HUNG AY et al.: Amyloid b-peptide is produced by cultured cells during normal metabolism. Nature (1992) 359:322-325.
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
-
81
-
-
0030300022
-
The 'nonamyloidogenic' p3 fragment (amyloid beta17-42) is a major constituent of Down's syndrome cerebellar preamyloid
-
LALOWSKI M, GOLABEK A, LEMERE CA et al.: The 'nonamyloidogenic' p3 fragment (amyloid beta17-42) is a major constituent of Down's syndrome cerebellar preamyloid. J. Biol. Chem. (1996) 271:33623-33631.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 33623-33631
-
-
Lalowski, M.1
Golabek, A.2
Lemere, C.A.3
-
82
-
-
0027198831
-
Molecular cloning of the cDNA for a human amyloid precursor protein homolog: Evidence for a multigene family
-
SPRECHER CA, GRANT FJ, GRIMM G et al.: Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family. Biochemistry (1993) 32:4481-4486. (Pubitemid 23143234)
-
(1993)
Biochemistry
, vol.32
, Issue.17
, pp. 4481-4486
-
-
Sprecher, C.A.1
Grant, F.J.2
Grimm, G.3
O'Hara, P.J.4
Norris, F.5
Norris, K.6
Foster, D.C.7
-
83
-
-
0027240503
-
Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid β protein precursor
-
DOI 10.1038/ng0993-95
-
WASCO W, GURUBHAGAVATULA S, PARADIS MD et al.: Isolation and characterization of the human APLP2 gene, encoding a homologue of the Alzheimer's associated b protein precursor. Nature Genet. (1993) 5:95-100. (Pubitemid 23261528)
-
(1993)
Nature Genetics
, vol.5
, Issue.1
, pp. 95-100
-
-
Wasco, W.1
Gurubhagavatula, S.2
Paradis, M.D.3
Romano, D.M.4
Sisodia, S.S.5
Hyman, B.T.6
Neve, R.L.7
Tanzi, R.E.8
-
84
-
-
0025365401
-
Platelet coagulation Factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein
-
SMITH RP, HIGUCHI DA, BROZE GJ: Platelet coagulation Factor XIa-inhibitor, a form of Alzheimer amyloid precursor protein. Science (1990) 248:1126-1128.
-
(1990)
Science
, vol.248
, pp. 1126-1128
-
-
Smith, R.P.1
Higuchi, D.A.2
Broze, G.J.3
-
85
-
-
0025371509
-
Protease nexin-II (amyloid b-protein precursor): A platelet a-granule protein
-
VAN NOSTRAND WE, SCHMAIER AH, FARROW JS, CUNNINGHAM DD: Protease nexin-II (amyloid b-protein precursor): a platelet a-granule protein. Science (1990) 248:745-748.
-
(1990)
Science
, vol.248
, pp. 745-748
-
-
Van Nostrand, W.E.1
Schmaier, A.H.2
Farrow, J.S.3
Cunningham, D.D.4
-
86
-
-
0024395366
-
Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts
-
DOI 10.1016/0092-8674(89)90096-2
-
SAITOH T, SUNDSMO MP, ROCH J et al.: Secreted form of amyloid b protein precursor is involved in the growth regulation of fibroblasts. Cell (1989) 58:615-622. (Pubitemid 19210955)
-
(1989)
Cell
, vol.58
, Issue.4
, pp. 615-622
-
-
Saitoh, T.1
Sundsmo, M.2
Roch, J.-M.3
Kimura, N.4
Cole, G.5
Schubert, D.6
Oltersdorf, T.7
Schenk, D.B.8
-
87
-
-
0027221517
-
Amino acid sequence RERMS represents the active domain of amyloid β/A4 protein precursor that promotes fibroblast growth
-
NINOMIYA H, ROCH J, SUNDSMO MP, OTERO DAC, SAITOH T: Amino acid sequence RERMS represents the active domain of amyloid b/A4 protein precursor that promotes fibroblast growth. J. Cell Biol. (1993) 121(4):879-886. (Pubitemid 23143548)
-
(1993)
Journal of Cell Biology
, vol.121
, Issue.4
, pp. 879-886
-
-
Ninomiya, H.1
Roch, J.-M.2
Sundsmo, M.P.3
Otero, D.A.C.4
Saitoh, T.5
-
88
-
-
0025759161
-
An antibody to the b amyloid and the amyloid precursor protein inhibits cell-substratum adhesion in many mammalian cell types
-
CHEN M, YANKNER BA: An antibody to the b amyloid and the amyloid precursor protein inhibits cell-substratum adhesion in many mammalian cell types. Neurosci. Lett. (1991) 125:223-226.
-
(1991)
Neurosci. Lett
, vol.125
, pp. 223-226
-
-
Chen, M.1
Yankner, B.A.2
-
89
-
-
0025965521
-
Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion
-
BREEN KC, BRUCE M, ANDERTON BH: Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion. J. Neurosci. Res. (1991) 28:90-100.
-
(1991)
J. Neurosci. Res
, vol.28
, pp. 90-100
-
-
Breen, K.C.1
Bruce, M.2
Anderton, B.H.3
-
90
-
-
0024810385
-
The regulation of amyloid b protein precursor secretion and its modulatory role in cell adhesion
-
SCHUBERT D, JIN L-W, SAITOH T,COLEG: The regulation of amyloid b protein precursor secretion and its modulatory role in cell adhesion. Neuron (1989) 3:689-694.
-
(1989)
Neuron
, vol.3
, pp. 689-694
-
-
Schubert, D.1
Jin, L.-W.2
Tcoleg, S.3
-
91
-
-
0027082156
-
A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion
-
GHISO J, ROSTAGNO A, GARDELLA JE et al.: A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence,-RHDS-, that promotes cell adhesion. Biochem. J. (1992) 288:1053-1059. (Pubitemid 23031794)
-
(1992)
Biochemical Journal
, vol.288
, Issue.3
, pp. 1053-1059
-
-
Ghiso, J.1
Rostagno, A.2
Gardella, J.E.3
Liem, L.4
Gorevic, P.D.5
Frangione, B.6
-
92
-
-
0028213567
-
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth
-
SMALL DH: A heparin binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth. J. Neurosci. (1994) 14:2117-2127. (Pubitemid 24108121)
-
(1994)
Journal of Neuroscience
, vol.14
, Issue.4
, pp. 2117-2127
-
-
Small, D.H.1
Nurcombe, V.2
Reed, G.3
Clarris, H.4
Moir, R.5
Beyreuther, K.6
Masters, C.L.7
-
93
-
-
0026663993
-
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth
-
MILWARD EA, PAPADOPOULOS R, FULLER SJ et al.: The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth. Neuron (1992) 9:129-137.
-
(1992)
Neuron
, vol.9
, pp. 129-137
-
-
Milward, E.A.1
Papadopoulos, R.2
Fuller, S.J.3
-
94
-
-
0026318496
-
Trophic effect of b-amyloid precursor protein on cerebral cortical neurons in culture
-
ARAKI W, KITAGUCHI N, TOKUSHIMA Y et al.: Trophic effect of b-amyloid precursor protein on cerebral cortical neurons in culture. Biochem. Biophys. Res. Commun. (1991) 181:265-271.
-
(1991)
Biochem. Biophys. Res. Commun
, vol.181
, pp. 265-271
-
-
Araki, W.1
Kitaguchi, N.2
Tokushima, Y.3
-
95
-
-
0028271689
-
The survival of rat cerebral cortical neurons in the presence of trophic APP peptides
-
YAMAMOTO K, MIYOSHI T, YAE T et al.: The survival of rat cerebral cortical neurons in the presence of trophic APP peptides. J. Neurobiol. (1994) 25:585-594. (Pubitemid 24129649)
-
(1994)
Journal of Neurobiology
, vol.25
, Issue.5
, pp. 585-594
-
-
Yamamoto, K.1
Miyoshi, T.2
Yae, T.3
Kawashima, K.4
Araki, H.5
Hanada, K.6
Otero, D.A.C.7
Roch, J.-M.8
Saitoh, T.9
-
96
-
-
0027478347
-
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
-
DOI 10.1016/0896-6273(93)90315-I
-
MATTSON MP, CHENG B, CULWELL AR et al.: Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the b-amyloid precursor protein. Neuron (1993) 10:243-254. (Pubitemid 23079546)
-
(1993)
Neuron
, vol.10
, Issue.2
, pp. 243-254
-
-
Mattson, M.P.1
Cheng, B.2
Culwell, A.R.3
Esch, F.S.4
Lieberburg, I.5
Rydel, R.E.6
-
97
-
-
0028175579
-
Secreted forms of b-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons
-
MATTSON MP: Secreted forms of b-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons. J. Neurobiol. (1994) 25:439-450.
-
(1994)
J. Neurobiol
, vol.25
, pp. 439-450
-
-
Mattson, M.P.1
-
98
-
-
0027447656
-
Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)
-
DOI 10.1038/362075a0
-
NISHIMOTO I, OKAMOTO T, MATSUURA Y et al.: Alzheimer amyloid protein precursor complexes with brain GTP-binding protein Go. Nature (1993) 362:75-79. (Pubitemid 23087295)
-
(1993)
Nature
, vol.362
, Issue.6415
, pp. 75-79
-
-
Nishimoto, I.1
Okamoto, T.2
Matsuura, Y.3
Takahashi, S.4
Okamoto, T.5
Murayama, Y.6
Ogata, E.7
-
99
-
-
0024543836
-
Amyloid β protein enhances the survival of hippocampal neurons in vitro
-
WHITSON JS, SELKOE DJ, COTMAN CW: Amyloid b protein enhances the survival of hippocampal neurons in vitro. Science (1989) 243:1488-1490. (Pubitemid 19087137)
-
(1989)
Science
, vol.243
, Issue.4897
, pp. 1488-1490
-
-
Whitson, J.S.1
Selkoe, D.J.2
Cotman, C.W.3
-
100
-
-
0026646328
-
In vivo neurotoxicity of beta amyloid [b(1-40)] and the b(25-35) fragment
-
KOWALL NW, MCKEE AC, YANKNER BA, BEAL MF: In vivo neurotoxicity of beta amyloid [b(1-40)] and the b(25-35) fragment. Neurobiol. Aging (1992) 13:537-542.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 537-542
-
-
Kowall, N.W.1
McKee, A.C.2
Yankner, B.A.3
Beal, M.F.4
-
101
-
-
0026702704
-
The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected b-amyloid in the rat brain
-
EMRE M, GEULA C, RANSIL BJ, MESULAM M-M: The acute neurotoxicity and effects upon cholinergic axons of intracerebrally injected b-amyloid in the rat brain. Neurobiol. Aging (1992) 13:553-559.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 553-559
-
-
Emre, M.1
Geula, C.2
Ransil, B.J.3
Mesulam, M.-M.4
-
102
-
-
0026644548
-
Intracerebral b-amyloid (25-35) produces tissue damage: Is it neurotoxic?
-
RUSH DK, ASCHIMIES S, MERRIMAN MC: Intracerebral b-amyloid (25-35) produces tissue damage: is it neurotoxic? Neurobiol. Aging (1992) 13:591-594.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 591-594
-
-
Rush, D.K.1
Aschimies, S.2
Merriman, M.C.3
-
103
-
-
0026756887
-
Methodological variables in the assessment of beta amyloid neurotoxicity
-
BUSCIGLIO J,LORENZOA,YANKNERBA: Methodological variables in the assessment of beta amyloid neurotoxicity. Neurobiol. Aging (1992) 13:609-612.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 609-612
-
-
Busciglio, J.1
Lorenzo, A.2
Yanknerba3
-
104
-
-
0026686938
-
Commentary and perspective on studies of beta amyloid neurotoxicity
-
YANKNER BA: Commentary and perspective on studies of beta amyloid neurotoxicity. Neurobiol. Aging (1992) 13:615-616.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 615-616
-
-
Yankner, B.A.1
-
105
-
-
0027447286
-
Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
-
PIKE CJ, BURDICK D, WALENCEWICZ AJ, GLABE CG, COTMAN CW: Neurodegeneration induced by b-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. (1993) 13(4):1676-1687. (Pubitemid 23095409)
-
(1993)
Journal of Neuroscience
, vol.13
, Issue.4
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
107
-
-
0028957882
-
Amyloid peptides are toxic via acommonoxidative mechanism
-
SCHUBERTD,BEHLC, LESLEYRet al.: Amyloid peptides are toxic via acommonoxidative mechanism. Proc. Natl. Acad. Sci. USA (1995) 92:1989-1993.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1989-1993
-
-
Schuber, T.D.1
Behl, C.2
Lesley, R.3
-
108
-
-
0028233494
-
Hydrogen peroxide mediates amyloid β protein toxicity
-
DOI 10.1016/0092-8674(94)90131-7
-
BEHL C, DAVIS JB, LESLEY R, SCHUBERT D: Hydrogen peroxide mediates amyloid b protein toxicity. Cell (1994) 77:817-827. (Pubitemid 24187680)
-
(1994)
Cell
, vol.77
, Issue.6
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
109
-
-
0029670094
-
Beta-Amyloid-mediated vasoactivity and vascular endothelial damage
-
THOMAS T, THOMAS G, MCLENDON C, SUTTON T, MULLAN M: beta-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature (1996) 380:168-171.
-
(1996)
Nature
, vol.380
, pp. 168-171
-
-
Thomas, T.1
Thomas, G.2
McLendon, C.3
Sutton, T.4
Mullan, M.5
-
110
-
-
0027129818
-
Vitamin e protects nerve cells from amyloid toxicity
-
BEHL C, DAVIS J, COLE GM, SCHUBERT D: Vitamin E protects nerve cells from amyloid toxicity. Biochem. Biophys. Res. Commun. (1992) 186(2):944-950.
-
(1992)
Biochem. Biophys. Res. Commun
, vol.186
, Issue.2
, pp. 944-950
-
-
Behl, C.1
Davis, J.2
Cole, G.M.3
Schubert, D.4
-
111
-
-
0013615899
-
RAGEand amyloid-beta peptide neurotoxicity in Alzheimer's disease
-
YANSD,CHENX,FUJ et al.:RAGEand amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature (1996) 382:685-691.
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
-
112
-
-
0029417023
-
Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
-
DOI 10.1038/378776a0
-
BUSCIGLIO J, YANKNER BA: Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature (1995) 378:776-779. (Pubitemid 26004408)
-
(1995)
Nature
, vol.378
, Issue.6559
, pp. 776-779
-
-
Busciglio, J.1
Yankner, B.A.2
-
113
-
-
0026570528
-
B-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
-
MATTSON MP, CHENG B, DAVIS D et al.: b-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. (1992) 12(2):376-389.
-
(1992)
J. Neurosci
, vol.12
, Issue.2
, pp. 376-389
-
-
Mattson, M.P.1
Cheng, B.2
Davis, D.3
-
114
-
-
0026778186
-
Amyloid b-protein fragment 25-35 causes activation of cytoplasmic calcium in neurons
-
JOSEPH R, HAN E: Amyloid b-protein fragment 25-35 causes activation of cytoplasmic calcium in neurons. Biochem. Biophys. Res. Commun. (1992) 184(3):1441-1447.
-
(1992)
Biochem. Biophys. Res. Commun
, vol.184
, Issue.3
, pp. 1441-1447
-
-
Joseph, R.1
Han, E.2
-
115
-
-
0028180304
-
Ca+2 channel blockers attenuate b-amyloid peptide toxicity to cortical neurons in culture
-
WEISS JH, PIKE CJ, COTMAN CW: Ca+2 channel blockers attenuate b-amyloid peptide toxicity to cortical neurons in culture. J. Neurochem. (1994) 62:372-375.
-
(1994)
J. Neurochem
, vol.62
, pp. 372-375
-
-
Weiss, J.H.1
Pike, C.J.2
Cotman, C.W.3
-
117
-
-
0025110182
-
β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage
-
DOI 10.1016/0006-8993(90)91355-K
-
KOH J,YANG LL,COTMAN CW:b-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res. (1990) 533:315-320. (Pubitemid 20377714)
-
(1990)
Brain Research
, vol.533
, Issue.2
, pp. 315-320
-
-
Koh, J.-Y.1
Yang, L.L.2
Cotman, C.W.3
-
118
-
-
0028204224
-
Calcium ionophore increases amyloid β peptide production by cultured cells
-
QUERFURTH HW, SELKOE DJ: Calcium ionophore increases amyloid b production by cultured cells. Biochemistry (1994) 33:4550-4561. (Pubitemid 24145103)
-
(1994)
Biochemistry
, vol.33
, Issue.15
, pp. 4550-4561
-
-
Querfurth, H.W.1
Selkoe, D.J.2
-
119
-
-
0024473819
-
2+ in toxic cell killing
-
ORRENIUS S, MCCONKEY DJ, BELLOMO G, NICOTERA P: Role of Ca2+ in toxic cell killing. Trends Pharmacol. Sci. (1989) 10:281-285. (Pubitemid 19189749)
-
(1989)
Trends in Pharmacological Sciences
, vol.10
, Issue.7
, pp. 281-285
-
-
Orrenius, S.1
McConkey, D.J.2
Bellomo, G.3
Nicotera, P.4
-
121
-
-
0026349379
-
Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons
-
MATTSON MP, ENGLE MG, RYCHLIK B: Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons. Mol. Chem. Neuropathol. (1991) 15:117-142.
-
(1991)
Mol. Chem. Neuropathol
, vol.15
, pp. 117-142
-
-
Mattson, M.P.1
Engle, M.G.2
Rychlik, B.3
-
122
-
-
0027429732
-
β-Amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins
-
BUSCIGLIO J, YEH J, YANKNER BA: b-amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins. J. Neurochem. (1993) 61:1565-1568. (Pubitemid 23285123)
-
(1993)
Journal of Neurochemistry
, vol.61
, Issue.4
, pp. 1565-1568
-
-
Busciglio, J.1
Yeh, J.2
Yankner, B.A.3
-
123
-
-
0030663141
-
Cerebrovascular degeneration is related to amyloid-β protein deposition in Alzheimer's disease
-
DOI 10.1111/j.1749-6632.1997.tb48478.x
-
KALARIA RN: Cerebrovascular degeneration is related to amyloid-b deposition in Alzheimer's disease. Ann. NY Acad. Sci. (1997) 826:263-271. (Pubitemid 27478048)
-
(1997)
Annals of the New York Academy of Sciences
, vol.826
, pp. 263-271
-
-
Kalaria, R.N.1
-
124
-
-
0021824223
-
Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation
-
SING CF, DAVIGNON J: Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation. Am. J. Hum. Genet. (1985) 37:268-285. (Pubitemid 15053161)
-
(1985)
American Journal of Human Genetics
, vol.37
, Issue.2
, pp. 268-285
-
-
Sing, C.F.1
Davignon, J.2
-
125
-
-
0030663143
-
The risk of dementia among persons with diabetes mellitus
-
LEIBSON CL, ROCCA WA, HANSON VA et al.: The risk of dementia among persons with diabetes mellitus. Ann. NY Acad. Sci. (1997) 826:422-427.
-
(1997)
Ann. NY Acad. Sci
, vol.826
, pp. 422-427
-
-
Leibson, C.L.1
Rocca, W.A.2
Hanson, V.A.3
-
126
-
-
0027404280
-
A population-based study of dementia in 85-year-olds
-
DOI 10.1056/NEJM199301213280301
-
SKOOG I, NILSSON L, PALMERTZ B, ANDREASSON L, SVANBORG A: A population-based study of dementia in 85-year-olds. New Engl. J. Med. (1993) 328:153-158. (Pubitemid 23021500)
-
(1993)
New England Journal of Medicine
, vol.328
, Issue.3
, pp. 153-158
-
-
Skoog, I.1
Nilsson, L.2
Palmertz, B.3
Andreasson, L.-A.4
Svanborg, A.5
-
127
-
-
9844226208
-
Coronary artery disease, hypertension, ApoE, and cholesterol: A link to Alzheimer's disease?
-
SPARKS DL: Coronary artery disease, hypertension, ApoE, and cholesterol: a link to Alzheimer's disease? Ann. NY Acad. Sci. (1997) 826:128-146.
-
(1997)
Ann. NY Acad. Sci
, vol.826
, pp. 128-146
-
-
Sparks, D.L.1
-
128
-
-
0022626051
-
Dementia after stroke
-
KOTILA M,WALTIMOO, NIEMI M-L,LAAKSONENR: Dementia after stroke. Eur. Neurol. (1986) 25:134-140. (Pubitemid 16168636)
-
(1986)
European Neurology
, vol.25
, Issue.2
, pp. 134-140
-
-
Kotila, M.1
Waltimo, O.2
Niemi, M.-L.3
Laaksonen, R.4
-
129
-
-
0028204944
-
Plasma lipids and cholesterol esterification in Alzheimer's disease
-
DOI 10.1016/0047-6374(94)90039-6
-
KNEBL J, DEFAZIO P, CLEARFIELD MB et al.: Plasma lipids and cholesterol esterification in Alzheimer's disease. Mech. Ageing Dev. (1994) 73:69-77. (Pubitemid 24070935)
-
(1994)
Mechanisms of Ageing and Development
, vol.73
, Issue.1
, pp. 69-77
-
-
Knebl, J.1
DeFazio, P.2
Clearfield, M.B.3
Little, L.4
McConathy, W.J.5
Mc Pherson, R.6
Lacko, A.G.7
-
131
-
-
0031976318
-
Serum total cholesterol, apolipoprotein E ε4 allele, and Alzheimer's disease
-
DOI 10.1159/000026149
-
NOTKOLA IL, SULKAVA R, PEKKANEN J et al.: Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease. Neuroepidemiology (1998) 17:14-20. (Pubitemid 28153361)
-
(1998)
Neuroepidemiology
, vol.17
, Issue.1
, pp. 14-20
-
-
Notkola, I.-L.1
Sulkava, R.2
Pekkanen, J.3
Erkinjuntti, T.4
Ehnholm, C.5
Kivinen, P.6
Tuomilehto, J.7
Nissinen, A.8
-
132
-
-
0032568552
-
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
-
DOI 10.1073/pnas.95.11.6460
-
SIMONS M, KELLER P, DE STROOPER B et al.: Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proc. Natl. Acad. Sci. USA (1998) 95:6460-6464. (Pubitemid 28249035)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
133
-
-
0032568843
-
Modulation of secreted β-amyloid β-peptide in brain by cholesterol
-
DOI 10.1074/jbc.273.26.16576
-
HOWLAND DS, TRUSKO SP, SAVAGE MJ et al.: Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. J. Biol. Chem. (1998) 273:16576-16582. (Pubitemid 28311445)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.26
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
Maedas, N.7
Siman, R.8
Greenberg, B.D.9
Scott, R.W.10
Flood, D.G.11
-
134
-
-
0029827792
-
Cholesterol protects PC12 cells from β-amyloid induced calcium disordering and cytotoxicity
-
ZHOU Y, RICHARDSON JS: Cholesterol protects PC12 cells from beta-amyloid induced calcium disordering and cytotoxicity. Neuroreport (1996) 7:2487-2490. (Pubitemid 26403002)
-
(1996)
NeuroReport
, vol.7
, Issue.15-17
, pp. 2487-2490
-
-
Zhou, Y.1
Richardson, J.S.2
-
135
-
-
79961063644
-
Histologic evidence implicating zinc in Alzheimer's disease
-
Submitted
-
SUH SW, JENSEN KB, JENSEN MS et al.: Histologic evidence implicating zinc in Alzheimer's disease. Science (1998). Submitted.
-
(1998)
Science
-
-
Suh, S.W.1
Jensen, K.B.2
Jensen, M.S.3
-
136
-
-
0027980901
-
Rapid induction of Alzheimer Aβ amyloid formation by zinc
-
BUSH AI, PETTINGELL WH, MULTHAUP G et al.: Rapid induction of Alzheimer Ab amyloid formation by zinc. Science (1994) 265:1464-1467. (Pubitemid 24306803)
-
(1994)
Science
, vol.265
, Issue.5177
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhaup, G.3
Paradis, M.D.4
Vonsattel, J.-P.5
Gusella, J.F.6
Beyreuther, K.7
Masters, C.L.8
Tanzi, R.E.9
-
137
-
-
0030704680
-
Zinc-induced Alzheimer's Aβ1-40 aggregation is mediated by conformational factors
-
DOI 10.1074/jbc.272.42.26464
-
HUANG X, ATWOOD CS, MOIR RD et al.: Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors. J. Biol. Chem. (1997) 272:26464-26470. (Pubitemid 27458865)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.42
, pp. 26464-26470
-
-
Huang, X.1
Atwood, C.S.2
Moir, R.D.3
Hartshorn, M.A.4
Vonsattel, J.-P.5
Tanzi, R.E.6
Bush, A.I.7
-
138
-
-
0032557425
-
Dramatic aggregation of alzheimer by Cu(II) is induced by conditions representing physiological acidosis
-
DOI 10.1074/jbc.273.21.12817
-
ATWOOD CS, MOIR RD, HUANG X et al.: Dramatic aggregation of Alzheimer Abeta by Cu(II) is induced by conditions representing physiological acidosis. J. Biol. Chem. (1998) 273:12817-12826. (Pubitemid 28246837)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.21
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
Scarpa, R.C.4
Bacarra, N.M.E.5
Romano, D.M.6
Hartshorn, M.A.7
Tanzi, R.E.8
Bush, A.I.9
-
139
-
-
79961061134
-
Solubilization of Alzheimer's disease cerebral Ab amyloid deposits by metal chelators
-
Submitted
-
CHERNY RA, LEGG JT, MCLEAN CA et al.: Solubilization of Alzheimer's disease cerebral Ab amyloid deposits by metal chelators. Science (1998). Submitted.
-
(1998)
Science
-
-
Cherny, R.A.1
Legg, J.T.2
McLean, C.A.3
-
140
-
-
0028180196
-
Modulation of Ab adhesiveness and secretase site cleavage by zinc
-
BUSH AI, PETTINGELL WH, PARADIS MD, TANZI RE: Modulation of Ab adhesiveness and secretase site cleavage by zinc. J. Biol. Chem. (1994) 269:12152-12158.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 12152-12158
-
-
Bush, A.I.1
Pettingell, W.H.2
Paradis, M.D.3
Tanzi, R.E.4
-
142
-
-
0000721418
-
Do the Timm sulphide silver method and the selenium method demonstrate zinc in the brain?
-
Frederickson CJ, Howell GA, Kasarskis EJ (Eds.), Liss
-
DANSCHER G: Do the Timm sulphide silver method and the selenium method demonstrate zinc in the brain? In: The Neurobiology of Zinc. Frederickson CJ, Howell GA, Kasarskis EJ (Eds.), Liss (1984).
-
(1984)
The Neurobiology of Zinc
-
-
Danscher, G.1
-
143
-
-
0021866385
-
Intravesicular localization of zinc in rat telencephalic boutons. A histochemical study
-
DOI 10.1016/0006-8993(85)91612-9
-
PEREZ-CLAUSELLJ,DANSCHERG: Intravesicular localization of zinc in rat telencephalic boutons: a histochemical study. Brain Res. (1985) 337:91-98. (Pubitemid 15008287)
-
(1985)
Brain Research
, vol.337
, Issue.1
, pp. 91-98
-
-
Perez-Clausell, J.1
Danscher, G.2
-
144
-
-
0021220724
-
Stimulation-induced uptake and release of zinc in hippocampal slices
-
HOWELL GA, WELCH MG, FREDERICKSON CJ: Stimulation-induced uptake and release of zinc in hippocampal slices. Nature (1984) 308:736-738. (Pubitemid 14127671)
-
(1984)
Nature
, vol.308
, Issue.5961
, pp. 736-738
-
-
Howell, G.A.1
Welch, M.G.2
Frederickson, C.J.3
-
145
-
-
0021996332
-
A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation
-
DOI 10.1016/0006-8993(85)90017-4
-
SLOVITER RS: A selective loss of hippocampal mossy fiber Timm stain accompanies granule cell seizure activity induced by perforant path stimulation. Brain Res. (1985) 330:150-153. (Pubitemid 15143651)
-
(1985)
Brain Research
, vol.330
, Issue.1
, pp. 150-153
-
-
Sloviter, R.S.1
-
146
-
-
0025138527
-
Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat
-
DOI 10.1016/0304-3940(90)90002-Q
-
TONDER N, JOHANSEN FF, FREDERICKSON CJ, ZIMMER J, DIEMER NH: Possible role of zinc in the selective degeneration of dentate hilar neurons after cerebral ischemia in the adult rat. Neurosci. Lett. (1990) 109:247-252. (Pubitemid 20056964)
-
(1990)
Neuroscience Letters
, vol.109
, Issue.3
, pp. 247-252
-
-
Tonder, B.1
Johansen, F.F.2
Frederickson, C.J.3
Zimmer, J.4
Diemer, N.H.5
-
147
-
-
0029777299
-
The role of zinc in selective neuronal death after transient global cerebral ischemia
-
KOH JY, SUH SW, GWAG BJ et al.: The role of zinc in selective neuronal death after transient global cerebral ischemia. Science (1996) 272:1013-1016. (Pubitemid 26259319)
-
(1996)
Science
, vol.272
, Issue.5264
, pp. 1013-1016
-
-
Koh, J.-Y.1
Suh, S.W.2
Gwag, B.J.3
He, Y.Y.4
Hsu, C.Y.5
Choi, D.W.6
-
148
-
-
0021287299
-
2+ from brain tissue during activity
-
ASSAF SY, CHUNG SH: Release of endogenous Zn2+ from brain tissue during activity. Nature (1984) 308:734-736. (Pubitemid 14127670)
-
(1984)
Nature
, vol.308
, Issue.5961
, pp. 734-736
-
-
Assaf, S.Y.1
Chung, S.H.2
-
149
-
-
0028168596
-
Secreted forms of b-amyloid precursor protein protect against ischemic brain injury
-
SMITH-SWINTOSKY VL, PETTIGREW LC, CRADDOCK SD et al.: Secreted forms of b-amyloid precursor protein protect against ischemic brain injury. J. Neurochem. (1994) 63:781-784.
-
(1994)
J. Neurochem
, vol.63
, pp. 781-784
-
-
Smith-Swintosky, V.L.1
Pettigrew, L.C.2
Craddock, S.D.3
-
150
-
-
0028179001
-
Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation
-
GREENBERG SM, KOO EH, SELKOE DJ, QIU WQ, KOSIK KS: Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation. Proc. Natl. Acad. Sci. USA (1994) 91:7104-7108.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7104-7108
-
-
Greenberg, S.M.1
Koo, E.H.2
Selkoe, D.J.3
Qiu, W.Q.4
Kosik, K.S.5
-
151
-
-
0030610645
-
Microglial activation by alzhelmer amyloid precursor protein and modulation by apolipoprotein E
-
DOI 10.1038/42257
-
BARGER SW, HARMON AD: Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature (1997) 388:878-881. (Pubitemid 27377060)
-
(1997)
Nature
, vol.388
, Issue.6645
, pp. 878-881
-
-
Barger, S.W.1
Harmon, A.D.2
-
152
-
-
0027373221
-
Muscarinic acetylcholine receptor subtypes associated with release of alzheimer amyloid precursor derivatives activate multiple signal transduction pathways
-
DOI 10.1111/j.1749-6632.1993.tb23020.x
-
FELDERCC,MAAL, BRILEY EM,AXELRODJ: Muscarinic acetylcholine receptor subtypes associated with release of Alzheimer amyloid precursor derivatives activate multiple signal transduction pathways. Ann. NY Acad. Sci. (1993) 695:15-18. (Pubitemid 23348229)
-
(1993)
Annals of the New York Academy of Sciences
, vol.695
, pp. 15-18
-
-
Felder, C.C.1
Ma, A.L.2
Briley, E.M.3
Axelrod, J.4
-
153
-
-
0027453490
-
Activation of protein kinase C inhibits cellular production of the amyloid β-protein
-
HUNG AY, HAASS C, NITSCH RM et al.: Activation of protein kinase C inhibits cellular production of the amyloid beta-protein. J. Biol. Chem. (1993) 268:22959-22962. (Pubitemid 23327996)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.31
, pp. 22959-22962
-
-
Hung, A.Y.1
Haass, C.2
Nitsch, R.M.3
Wei Qiao Qiu4
Citron, M.5
Wurtman, R.J.6
Growdon, J.H.7
Selkoe, D.J.8
-
154
-
-
0028246846
-
The release of Alzheimer's disease β amyloid peptide is reduced by phorbol treatment
-
JACOBSEN JS, SPRUYT MA, BROWN AM et al.: The release of Alzheimer's disease b-amyloid is reduced by phorbol treatment. J. Biol. Chem. (1994) 269:8376-8382. (Pubitemid 24200256)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.11
, pp. 8376-8382
-
-
Jacobsen, J.S.1
Spruyt, M.A.2
Brown, A.M.3
Sahasrabudhe, S.R.4
Blume, A.J.5
Vitek, M.P.6
Muenkel, H.A.7
Sonnenberg-Reines, J.8
-
156
-
-
0027332657
-
Inhibition of b-amyloid production by activation of protein kinase C
-
GABUZDA D, BUSCIGLIO J, YANKNER BA: Inhibition of b-amyloid production by activation of protein kinase C. J. Neurochem. (1993) 61:2326-2329.
-
(1993)
J. Neurochem
, vol.61
, pp. 2326-2329
-
-
Gabuzda, D.1
Busciglio, J.2
Yankner, B.A.3
-
157
-
-
0028207004
-
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner
-
BUXBAUM JD, RUEFLI AA,PARKER CA, CYPESS AM,GREENGAR DP: Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner. Proc. Natl. Acad. Sci. USA (1994) 91:4489-4493. (Pubitemid 24143459)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.10
, pp. 4489-4493
-
-
Buxbaum, J.D.1
Ruefli, A.A.2
Parker, C.A.3
Cypess, A.M.4
Greengard, P.5
-
158
-
-
0030028598
-
Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion
-
NITSCH RM, DENG M, GROWDON JH, WURTMAN RJ: Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion. J. Biol. Chem. (1998) 271:4188-4194.
-
(1998)
J. Biol. Chem
, vol.271
, pp. 4188-4194
-
-
Nitsch, R.M.1
Deng, M.2
Growdon, J.H.3
Wurtman, R.J.4
-
159
-
-
0028342424
-
Estrogen regulates metabolism of Alzheimer amyloid β precursor protein
-
JAFFE AB, TORAN-ALLERAND CD, GREENGARD P, GANDY SE: Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein. J. Biol. Chem. (1994) 269:13065-13068. (Pubitemid 24206062)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.18
, pp. 13065-13068
-
-
Jaffe, A.B.1
Toran-Allerand, C.D.2
Greengard, P.3
Gandy, S.E.4
-
160
-
-
0030790252
-
Metabotropic glutamate receptor subtype mGlur1α stimulates the secretion of the amyloid β-protein precursor ectodomain
-
NITSCH RM, DENG A, WURTMAN RJ, GROWDON JH: Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain. J. Neurochem. (1997) 69:704-712. (Pubitemid 27327973)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.2
, pp. 704-712
-
-
Nitsch, R.M.1
Deng, A.2
Wurtman, R.J.3
Growdon, J.H.4
-
161
-
-
0031898094
-
Vasopressin and bradykinin regulate secretory processing of the amyloid protein precursor of Alzheimer's disease
-
DOI 10.1023/A:1022423813362
-
NITSCH RM, KIM C, GROWDON JH: Vasopressin and bradykinin regulate secretory processing of the amyloid protein precursor of Alzheimer's disease. Neurochem. Res. (1998) 23:807-814. (Pubitemid 28173588)
-
(1998)
Neurochemical Research
, vol.23
, Issue.5
, pp. 807-814
-
-
Nitsch, R.M.1
Kim, C.2
Growdon, J.H.3
-
162
-
-
0029671454
-
Cholesterol modulates a-secretase cleavage of amyloid precursor protein
-
BODOVITZ S, KLEIN WL: Cholesterol modulates a-secretase cleavage of amyloid precursor protein. J. Biol. Chem. (1996) 271:4436-4440.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
163
-
-
0027209083
-
Release of amyloid β-protein precursor derivatives by electrical depolarization of rat hippocampal slices
-
NITSCH RM, FARBER SA, GROWDON JH, WURTMAN RJ: Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proc. Natl. Acad. Sci. USA (1993) 90:5191-5193. (Pubitemid 23183003)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.11
, pp. 5191-5193
-
-
Nitsch, R.M.1
Farber, S.A.2
Growdon, J.H.3
Wurtman, R.J.4
-
164
-
-
0027956042
-
Amyloid precursor protein secretion and βA4 amyloid generation are not mutually exclusive
-
DOI 10.1016/0014-5793(94)00671-7
-
DYRKS T, MONNING U, BEYREUTHER K, TURNER J: Amyloid precursor protein secretion and bA4 amyloid generation are not mutually exclusive. FEBS Lett. (1994) 349:210-214. (Pubitemid 24263264)
-
(1994)
FEBS Letters
, vol.349
, Issue.2
, pp. 210-214
-
-
Dyrks, T.1
-
165
-
-
0030956630
-
Muscarinic agonists in Alzheimer's disease
-
DOI 10.1016/S0024-3205(97)00039-8, PII S0024320597000398
-
GROWDON JH: Muscarinic agonists in Alzheimer's disease. Life Sci. (1997) 60:993-998. (Pubitemid 27165567)
-
(1997)
Life Sciences
, vol.60
, Issue.13-14
, pp. 993-998
-
-
Growdon, J.H.1
-
166
-
-
0028971033
-
Regulated secretion of beta-amyloid precursor protein in rat brain
-
FARBER SA, NITSCH RM, SCHULZ JG, WURTMAN RJ: Regulated secretion of beta-amyloid precursor protein in rat brain. J. Neurosci. (1995) 15:7442-7451. (Pubitemid 3010080)
-
(1995)
Journal of Neuroscience
, vol.15
, Issue.11
, pp. 7442-7451
-
-
Farber, S.A.1
Nitsch, R.M.2
Schulz, J.G.3
Wurtman, R.J.4
-
167
-
-
0027421610
-
Receptor-coupled amyloid precursor protein processing
-
DOI 10.1111/j.1749-6632.1993.tb23039.x
-
NITSCH RM, SLACK BE, FARBER SA et al.: Receptor-coupled amyloid precursor protein processing. Ann. NY Acad. Sci. (1993) 695:122-127. (Pubitemid 23348248)
-
(1993)
Annals of the New York Academy of Sciences
, vol.695
, pp. 122-127
-
-
Nitsch, R.M.1
Slack, B.E.2
Farber, S.A.3
Borghesani, P.R.4
Schulz, J.G.5
Kim, C.6
Felder, C.C.7
Growdon, J.H.8
Wurtman, R.J.9
-
169
-
-
0023943181
-
Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease
-
ARAUJO DM, LAPCHAK PA, ROBITAILLE Y, GAUTHIER S, QUIRION R: Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease. J. Neurochem. (1988) 50:1914-1923.
-
(1988)
J. Neurochem
, vol.50
, pp. 1914-1923
-
-
Araujo, D.M.1
Lapchak, P.A.2
Robitaille, Y.3
Gauthier, S.4
Quirion, R.5
-
170
-
-
1842407763
-
Autoradiographic distribution of M1, M2, M3, and m4 muscarinic receptor subtypes in Alzheimer's disease
-
DOI 10.1002/(SICI)1098-2396(199708)26:4<341::AID-SYN2>3.0.CO;2-6
-
RODRIGUEZ-PUERTAS R, PASCUAL J, VILARO T, PAZOS A: Autoradiographic distribution of M1, M2, M3, and M4 muscarinic receptor subtypes in Alzheimer's disease. Synapse (1997) 26:341-350. (Pubitemid 27284105)
-
(1997)
Synapse
, vol.26
, Issue.4
, pp. 341-350
-
-
Rodriguez-Puertas, R.1
Pascual, J.2
Vilaro, T.3
Pazos, A.4
-
171
-
-
0028924664
-
Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease
-
FLYNN DD, FERRARI-DILEO G, MASH DC, LEVEY AI: Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. J. Neurochem. (1995) 64:1888-1891.
-
(1995)
J. Neurochem
, vol.64
, pp. 1888-1891
-
-
Flynn, D.D.1
Ferrari-Dileo, G.2
Mash, D.C.3
Levey, A.I.4
-
172
-
-
0032523039
-
Protein kinase C activation increases release of secreted amyloid precursor protein without decreasing Aβ production in human primary neuron cultures
-
LEBLANCA C,KOUTROUMANI SM,GOODYER CG: Protein kinaseCactivation increases release of secreted amyloid precursor protein without decreasing Abeta production in human primary neuron cultures. J. Neurosci. (1998) 18:2907-2913. (Pubitemid 28163220)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.8
, pp. 2907-2913
-
-
LeBlanc, A.C.1
Koutroumanis, M.2
Goodyer, C.G.3
-
173
-
-
28744448953
-
Selective signaling via novel muscarinic agonists: Implications for Alzheimer's disease treatments and clinical update
-
Springfield, IL, USA
-
FISHER A, HELDMAN E, GURWITZ D et al.: Selective signaling via novel muscarinic agonists: implications for Alzheimer's disease treatments and clinical update. Third Springfield International Symposium on Alzheimer's Disease. Springfield, IL, USA (1994).
-
(1994)
Third Springfield International Symposium on Alzheimer's Disease
-
-
Fisher, A.1
Heldman, E.2
Gurwitz, D.3
-
174
-
-
0030686570
-
The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease
-
BODICK NC, OFFEN WW, SHANNON HE et al.: The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer's disease. Alzheimer's Dis. Assoc. Disord. (1997) 11(Suppl. 4):S16-S22. (Pubitemid 27453885)
-
(1997)
Alzheimer Disease and Associated Disorders
, vol.11
, Issue.SUPPL. 4
-
-
Bodick, N.C.1
Offen, W.W.2
Shannon, H.E.3
Satterwhite, J.4
Lucas, R.5
Van Lier, R.6
Paul, S.M.7
-
175
-
-
0024561561
-
Diffuse type of senile plaques in the cerebellum of Alzheimer-type dementia demonstrated by β protein immunostain
-
DOI 10.1007/BF00687584
-
YAMAGUCHI H, HIRAI S, MORIMATSU M, SHOJI M, NAKAZATO Y: Diffuse type of senile plaques in the cerebellum of Alzheimer-type dementia demonstrated by beta protein immunostain. Acta Neuropathol. (Berl.) (1989) 77:314-319. (Pubitemid 19044199)
-
(1989)
Acta Neuropathologica
, vol.77
, Issue.3
, pp. 314-319
-
-
Yamaguchi, H.1
Hirai, S.2
Morimatsu, M.3
Shoji, M.4
Nakazato, Y.5
-
176
-
-
0023425365
-
Synthetic peptide homologous to beta protein from Alzheimer's disease forms amyloid-like fibrils in vitro
-
KIRSCHNER DA, INOUYE H, DUFFY LK et al.: Synthetic peptide homologous to beta protein from Alzheimer's disease forms amyloid-like fibrils in vitro. Proc. Natl. Acad. Sci. USA (1987) 84:6953-6957.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 6953-6957
-
-
Kirschner, D.A.1
Inouye, H.2
Duffy, L.K.3
-
177
-
-
0029994633
-
Arrest of β-amyloid fibril formation by a pentapeptide ligand
-
DOI 10.1074/jbc.271.15.8545
-
TJERNBERGLO,NASLUNDJ, LINDQVIST F et al.: Arrest of b-amyloid fibril formation by a pentapeptide ligand. J. Biol. Chem. (1996) 271:8545-8548. (Pubitemid 26123269)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.15
, pp. 8545-8548
-
-
Tjernberg, L.O.1
Naslundt, J.2
Lindqvist, F.3
Johansson, J.4
Karlstrom, A.R.5
Thyberg, J.6
Tereniust, L.7
Nordstedt, C.8
-
178
-
-
0025296269
-
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage
-
LEVY E, CARMAN MD, FERNANDEZ-MADRID IJ et al.: Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch-type. Science (1990) 248:1124-1126.
-
(1990)
Dutch-type. Science
, vol.248
, pp. 1124-1126
-
-
Levy, E.1
Carman, M.D.2
Fernandez-Madrid, I.J.3
-
179
-
-
0026453127
-
Fibril formation by primate, rodent, and dutch-hemorrhagic analogues of Alzheimer amyloid b-protein
-
FRASER PE, NGUYEN JT, INOUYE H et al.: Fibril formation by primate, rodent, and dutch-hemorrhagic analogues of Alzheimer amyloid b-protein. Biochemistry (1992) 31:10716-10723.
-
(1992)
Biochemistry
, vol.31
, pp. 10716-10723
-
-
Fraser, P.E.1
Nguyen, J.T.2
Inouye, H.3
-
180
-
-
0026595567
-
Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs
-
BURDICK D, SOREGHAN B, KWON M et al.: Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs. J. Biol. Chem. (1992) 267:546-554.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 546-554
-
-
Burdick, D.1
Soreghan, B.2
Kwon, M.3
-
181
-
-
0025779179
-
Solution structures of β peptide and its constituent fragments: Relation to amyloid deposition
-
BARROW CJ, ZAGORSKI MG: Solution structures of b peptide and its constituent fragments: relation to amyloid deposition. Science (1991) 253:179-182. (Pubitemid 21917135)
-
(1991)
Science
, vol.253
, Issue.5016
, pp. 179-182
-
-
Barrow, C.J.1
Zagorski, M.G.2
-
183
-
-
0027195933
-
Seeding 'one-dimensional crystallization' of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
-
DOI 10.1016/0092-8674(93)90635-4
-
JARRETT JT, LANSBURY PT, Jr.: Seeding 'one-dimensional crystallization' of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell (1993) 73:1055-1058. (Pubitemid 23180480)
-
(1993)
Cell
, vol.73
, Issue.6
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury Jr., P.T.2
-
184
-
-
0027006436
-
Amyloid fibril formation requires a chemically discriminating nucleation event: Studies of an amyloidogenic sequence from the bacterial protein OsmB
-
DOI 10.1021/bi00164a008
-
JARRETT JT, LANSBURY PT, Jr.: Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB. Biochemistry (1992) 31:12345-12352. (Pubitemid 23163109)
-
(1992)
Biochemistry
, vol.31
, Issue.49
, pp. 12345-12352
-
-
Jarrett, J.T.1
Lansbury Jr., P.T.2
-
185
-
-
0026619343
-
Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease βA4 peptides
-
DOI 10.1016/0022-2836(92)90835-8
-
HILBICH C, KISTERS-WOIKE B, REED J, MASTERS CL, BEYREUTHER K: Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease bA4 peptides. J. Mol. Biol. (1992) 228:460-473. (Pubitemid 23007569)
-
(1992)
Journal of Molecular Biology
, vol.228
, Issue.2
, pp. 460-473
-
-
Hilbich, C.1
Kisters-Woike, B.2
Reed, J.3
Masters, C.L.4
Beyreuther, K.5
-
186
-
-
0028978227
-
Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation
-
GUPTA-BANSAL R, FREDERICKSON RC, BRUNDEN KR: Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation. J. Biol. Chem. (1995) 270:18666-18671.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 18666-18671
-
-
Gupta-Bansal, R.1
Frederickson, R.C.2
Brunden, K.R.3
-
187
-
-
0030725311
-
Perlecan binds to the β-amyloid proteins (aβ) of Alzheimer's disease, accelerates aβ fibril formation, and maintains aβ fibril stability
-
CASTILLO GM, NGO C, CUMMINGS J, WIGHT TN, SNOW AD: Perlecan binds to the beta-amyloid proteins (A beta) of Alzheimer's disease, accelerates A beta fibril formation, and maintains A beta fibril stability. J. Neurochem. (1997) 69:2452-2465. (Pubitemid 27495432)
-
(1997)
Journal of Neurochemistry
, vol.69
, Issue.6
, pp. 2452-2465
-
-
Castillo, G.M.1
Ngo, C.2
Cummings, J.3
Wight, T.N.4
Snow, A.D.5
-
189
-
-
0031938180
-
Heparin oligosaccharides that pass the blood-brain barrier inhibit β- amyloid precursor protein secretion and heparin binding to β-amyloid peptide
-
LEVEUGLE B, DING W, LAURENCE F et al.: Heparin oligosaccharides that pass the blood-brain barrier inhibit beta-amyloid precursor protein secretion and heparin binding to beta-amyloid peptide. J. Neurochem. (1998) 70:736-744. (Pubitemid 28079364)
-
(1998)
Journal of Neurochemistry
, vol.70
, Issue.2
, pp. 736-744
-
-
Leveugle, B.1
Ding, W.2
Laurence, F.3
Dehouck, M.-P.4
Scanameo, A.5
Cecchelli, R.6
Fillit, H.7
-
190
-
-
0031973005
-
Congo red inhibits proteoglycan and serum amyloid P binding to amyloid β fibrils
-
GUPTA-BANSAL R, BRUNDEN KR: Congo red inhibits proteoglycan and serum amyloid P binding to amyloid beta fibrils. J. Neurochem. (1998) 70:292-298. (Pubitemid 28020855)
-
(1998)
Journal of Neurochemistry
, vol.70
, Issue.1
, pp. 292-298
-
-
Gupta-Bansal, R.1
Brunden, K.R.2
-
191
-
-
0028245211
-
Melatonin as a free radical scavenger: Implications for aging and age-related diseases
-
REITER RJ, TAN D-X, POEGGELER B et al.: Melatonin as a free radical scavenger: implications for aging and age-related diseases. Ann. NY Acad. Sci. (1998) 719:1-12. (Pubitemid 24199963)
-
(1994)
Annals of the New York Academy of Sciences
, vol.719
, pp. 1-12
-
-
Reiter, R.J.1
Tan, D.-X.2
Poeggeler, B.3
Menendez-Pelaez, A.4
Chen, L.-D.5
Saarela, S.6
-
192
-
-
0002979059
-
Melatonin: A potent, endogenous hydroxyl radical scavenger
-
TAN D-X,CHEN L-D, POEGGELER B,MANCHESTER LC, REITER RJ: Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr. J. (1993) 1:57-60.
-
(1993)
Endocr. J
, vol.1
, pp. 57-60
-
-
Tan, D.-X.1
Chen, L.-D.2
Poeggeler, B.3
Manchester, L.C.4
Reiter, R.J.5
-
193
-
-
0027201993
-
The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo
-
TAN D-X, POEGGELER B, REITER RJ et al.: The pineal hormone melatonin inhibits DNA adduct formation induced by the chemical carcinogen safrole in vivo. Cancer Lett. (1993) 70:65-71. (Pubitemid 23219861)
-
(1993)
Cancer Letters
, vol.70
, Issue.1-2
, pp. 65-71
-
-
Tan, D.-X.1
Poeggeler, B.2
Reiter, R.J.3
Chen, L.-D.4
Chen, S.5
Manchester, L.C.6
Barlow-Walden, L.R.7
-
194
-
-
0019209714
-
Pineal melatonin rhythm: Reduction in aging Syrian hamsters
-
REITER RJ, RICHARDSON BA, JOHNSON CY, FERGUSON BN, DINH DT: Pineal melatonin rhythm: reduction in aging Syrian hamsters. Science (1980) 210:1372-1373. (Pubitemid 11175499)
-
(1980)
Science
, vol.210
, Issue.4476
, pp. 1372-1373
-
-
Reiter, R.J.1
Richardson, B.A.2
Johnson, L.Y.3
-
195
-
-
0028352974
-
Chrono-neuroendocrinological aspects of physiological aging and senile dementia
-
DORI D, CASALE G, SOLERTE SB et al.: Chrono-neuroendocrinological aspects of physiological aging and senile dementia. Chronobiologia (1994) 21:121-126. (Pubitemid 24165064)
-
(1994)
Chronobiologia
, vol.21
, Issue.1-2
, pp. 121-126
-
-
Dori, D.1
Casale, G.2
Solerte, S.B.3
Fioravanti, M.4
Migliorati, G.5
Cuzzoni, G.6
Ferrari, E.7
-
196
-
-
0031053554
-
Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide
-
PAPPOLLA M, SOS M, OMAR RA et al.: Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. J. Neurosci. (1997) 17:1683-1690. (Pubitemid 27089813)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.5
, pp. 1683-1690
-
-
Pappolla, M.A.1
Sos, M.2
Omar, R.A.3
Bick, R.J.4
Hickson-Bick, D.L.M.5
Reiter, R.J.6
Efthimiopoulos, S.7
Robakis, N.K.8
-
197
-
-
0032571381
-
Inhibition of Alzheimer beta-fibrillogenesis by melatonin
-
PAPPOLLA M, BOZNER P, SOTO C et al.: Inhibition of Alzheimer beta-fibrillogenesis by melatonin. J. Biol. Chem. (1998) 273:7185-7188.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 7185-7188
-
-
Pappolla, M.1
Bozner, P.2
Soto, C.3
-
198
-
-
0031960665
-
Melatonin prevents β-amyloid-induced lipid peroxidation
-
DOI 10.1111/j.1600-079X.1998.tb00370.x
-
DANIELS WM, VAN RENSBURG SJ, VAN ZYL JM, TALJAARD JJ: Melatonin prevents beta-amyloid-induced lipid peroxidation. J. Pineal Res. (1998) 24:78-82. (Pubitemid 28168318)
-
(1998)
Journal of Pineal Research
, vol.24
, Issue.2
, pp. 78-82
-
-
Daniels, W.M.U.1
Van Rensburg, S.J.2
Van Zyl, J.M.3
Taljaard, J.J.F.4
-
199
-
-
0031044352
-
Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: Involvement of insulin-degrading enzyme
-
MCDERMOTT JR, GIBSON AM: Degradation of Alzheimer's beta-amyloid protein by human and rat brain peptidases: involvement of insulin-degrading enzyme. Neurochem. Res. (1997) 22:49-56.
-
(1997)
Neurochem. Res
, vol.22
, pp. 49-56
-
-
McDermott, J.R.1
Gibson, A.M.2
-
200
-
-
0029804989
-
Degradation of Alzheimer's β-amyloid protein by human cathepsin D
-
MCDERMOTT JR, GIBSON AM: Degradation of Alzheimer's beta-amyloid protein by human cathepsin D. Neuroreport (1996) 7:2163-2166. (Pubitemid 26361838)
-
(1996)
NeuroReport
, vol.7
, Issue.13
, pp. 2163-2166
-
-
McDermott, J.R.1
Gibson, A.M.2
-
201
-
-
0030569293
-
Cathepsin D is involved in the clearance of Alzheimer's β-amyloid protein
-
DOI 10.1016/0014-5793(96)01087-3, PII S0014579396010873
-
HAMAZAKI H: Cathepsin D is involved in the clearance of Alzheimer's beta-amyloid. FEBS Lett. (1996) 396:139-142. (Pubitemid 26377812)
-
(1996)
FEBS Letters
, vol.396
, Issue.2-3
, pp. 139-142
-
-
Hamazaki, H.1
-
202
-
-
0031890884
-
Proteolytic degradation of Alzheimer's disease amyloid β-peptide by a metalloproteinase from microglia cells
-
MENTLEI NR,LUDWIG R,MARTENSEN I: Proteolytic degradation of Alzheimer's disease amyloid b-peptide by a metalloproteinase from microglia cells. J. Neurochem. (1998) 70:721-726. (Pubitemid 28079362)
-
(1998)
Journal of Neurochemistry
, vol.70
, Issue.2
, pp. 721-726
-
-
Mentlein, R.1
Ludwig, R.2
Martensen, I.3
-
203
-
-
0030248270
-
Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via a scavenger receptor
-
DOI 10.1016/S0896-6273(00)80187-7
-
PARESCE DM, GHOSH RN, MAXFIELD FR: Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor. Neuron (1996) 17:553-565. (Pubitemid 26322226)
-
(1996)
Neuron
, vol.17
, Issue.3
, pp. 553-565
-
-
Paresce, D.M.1
Ghosh, R.N.2
Maxfield, F.R.3
-
204
-
-
0013642132
-
2-macroglobulin complex
-
DOI 10.1074/jbc.271.14.8443
-
QIU WQ, BORTH W, YE Z et al.: Degradation of amyloid b-protein by a serine protease-a2-macroglobulin complex. J. Biol. Chem. (1996) 271:8443-8451. (Pubitemid 26108682)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.14
, pp. 8443-8451
-
-
Qiu, W.Q.1
Borth, W.2
Ye, Z.3
Haass, C.4
Teplow, D.B.5
Selkoe, D.J.6
-
206
-
-
0011956385
-
Chronic inflammatory mechanisms of the brain: Implications for the treatment of Alzheimer's disease
-
MCGEER PL, MCGEER EG: Chronic inflammatory mechanisms of the brain: implications for the treatment of Alzheimer's disease. Dementia (1995) 9:111-123.
-
(1995)
Dementia
, vol.9
, pp. 111-123
-
-
McGeer, P.L.1
McGeer, E.G.2
-
209
-
-
0030000385
-
The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease
-
DOI 10.1146/annurev.med.47.1.401
-
BREITNER JCS: The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease. Ann. Rev. Med. (1996) 47:401-411. (Pubitemid 26138900)
-
(1996)
Annual Review of Medicine
, vol.47
, pp. 401-411
-
-
Breitner, J.C.S.1
-
210
-
-
0002820657
-
Adrenocorticotropic hormone; Adrenocortical steroids and their synthetic analogs; Inhibitors of the synthesis and the actions of adrenocortical hormones
-
Gilman AG, Rall TW, Nies AS, Taylor P (Eds.), Pergamon Press
-
HAYNES RC: Adrenocorticotropic hormone; adrenocortical steroids and their synthetic analogs; inhibitors of the synthesis and the actions of adrenocortical hormones. In: The Pharmacological Basis of Therapeutics. Gilman AG, Rall TW, Nies AS, Taylor P (Eds.), Pergamon Press (1990).
-
(1990)
The Pharmacological Basis of Therapeutics
-
-
Haynes, R.C.1
-
212
-
-
0029907548
-
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
-
DOI 10.1038/383550a0
-
GOEDERT M, JAKES R, SPILLANTINI MG et al.: Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature (1996) 383:550-553. (Pubitemid 26346185)
-
(1996)
Nature
, vol.383
, Issue.6600
, pp. 550-553
-
-
Goedert, M.1
Jakes, R.2
Spillantini, M.G.3
Hasegawa, M.4
Smith, M.J.5
Crowther, R.A.6
-
214
-
-
0031439109
-
Alzheimer-like changes in microtubule-associated protein tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding stimulation of phosphorylation filament assembly depend on the degree of sulfation
-
DOI 10.1074/jbc.272.52.33118
-
HASEGAWA M, CROWTHER RA, JAKES R, GOEDERT M: Alzheimer-like changes in microtubule-associated protein tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation. J. Biol. Chem. (1997) 272:33118-33124. (Pubitemid 28023655)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.52
, pp. 33118-33124
-
-
Hasegawa, M.1
Crowther, R.A.2
Jakes, R.3
Goedert, M.4
|