Neurotoxic Effect of Copper Salts in Rats

Polish Journal of Environmental Studies

Volumn 9, Issue 4, 2000, Pages 301-304

  Plech, A ^a   Klimkiewicz, T ^a   Jakrzewska, H ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Copper ions; Neurotoxic effects in rats; Spatial memory; Water maze test

Indexed keywords

EID: 0007864764     PISSN: 12301485     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. NORDBERG G.F.: Neurotoxic effect of metals and their compounds. Advances in Neurotoxicology ed. L. Manzo, N. Levy, Y. Lacasse, L. Roche, Pergamon Press, Oxford pp. 3-15, 1980.
2. DE VRIES D. J., SEWELL R. B., BEAST P. M.: Effect of copper on dopaminergic function in the rat corpus striatum. Exp. Neurol. 91, 546, 1986.
3. PROHASKA J. R., BAILEY W. R.: Regional specificity in alternations of rat brain copper and catecholamines. J. Neurochem. 63, 1551, 1994.
4. BRUS R., MENGEL K., BARANIAK Z., RZESZOTARSKA B., MASIUKIEWICZ E., KOWALSKA I., JAKRZEWSKA H., PLECH A.: Neurotoksyczne efekty miedziowego kompleksu gonadoliberyny (Cu-LH-RH) u szczurów. Konferencja naukowa jakość badań w toksykologii, Supraśl k. Białegostoku, 3-4 czerwca 1993, 37.
5. JANSSEN P.A.J., JAGENAU A.H.M., SCHELLEKENS K.H.L.: Chemistry and pharmacology of compounds related to 4-(4-hydroxy)-4-phenylpiperidino-butyrophenone. Part IV. Influence of haloperidol (R1025) and chlorpromazine on the behaviour of rat in unfamiliar̀ open field' situation. Psychopharmacology 1, 389-392, 1960.
6. MORRIS R.: Development of a water maze procedure for studying spatial learning in the rat. J. Neurosci. Methods 11, 47, 1984.
7. SAITO T., NAGAO T., OKABE M., SAITO K.: Neurochemical and histochemical evidence for an abnormal catecholamines metabolism in the cerebral cortex of the Long-Evans Cinnamon rat before excessive copper accumulation in the brain. Neurosci. Lett. 216, 195, 1996.
8. DARWITA RR.: Changes in brain neurotransmitters in hypothalamus related to feeding behaviour in LEC rat. Hokkaido-Igaku-Zasshi 71, 377, 1996.
9. PLECH A., RZESZOTARSKA B., KOWALSKA I.: Central effects of nickel complex LH-RH in rats, (unpublished data).