Reviewing apramycin's properties and use in controlling colibacillosis in pigs

Veterinary Medicine

Volumn 91, Issue 5, 1996, Pages 473-477

  Mortensen, Joel E ^a   Nanavaty, Jaydeep ^b   Veenhuizen, Melissa Fleck ^c   Shryock, Thomas R ^d  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c ELANCO ANIMAL HEALTH   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0007744817     PISSN: 87507943     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Muller, R.D.: Apralan Premix Technical Manual: Apralan Premix, Apramycin Sulfate. Elanco Products Company, Indianapolis, Ind., 1986; pp 16-29.
2. Edson, R.S.; Terrell, C.L.: The Aminoglycosides. Mayo Clinic Proc. 66:1158-1164; 1991.
3. Brewer, N.S.: The Aminoglycosides - Streptomycin, Kanamycin, Gentamicin, Tobramycin, Amikacin, Neomycin. Mayo Clinic Proc. 52:675-679; 1977.
4. Davies, J.; O'Connor, S.: Enzymatic Modification of Aminoglycoside Antibiotics: 3-N-acetyltransferase with Broad Specificity that Determines Resistance to Novel Aminoglycoside Apramycin. Antimicrob. Agents Chemother. 14:69-72; 1978.
5. Ziv, G. et al: Clinical Pharmacology of Apramycin in Calves. J. Vet. Pharmacol. Ther. 8:95-104; 1985.
6. Walton, J.R.: Apramycin, a New Aminocyclitol Antibiotic. J. Antimicrob. Chemother. 4:309-313; 1978.
7. Stark, W.M. et al: Nebramycin, 3 New Broadspectrum Antibiotic Complex 1. Detection and Biosynthesis. Antimicrob. Agents Chemother. 8:314-323; 1968.
8. O'Connor, S. et al: Apramycin, a Unique Aminocyclitol Antibiotic. J. Organic Chem. 41:2087-2092; 1976.
9. Perzynski, S. et al: Effects of Apramycin, a Novel Aminoglycoside Antibiotic on Bacterial Protein Synthesis. Eur. J. Biochem. 99:623-628; 1979.
10. Ryden, R.; Moore, B.J.: The In Vitro Activity of Apramycin, a New Aminocyclitol Antibiotic. J. Antimicrob. Chemother. 3:609-613; 1977.
11. Gorham, P.E. et al: Dosage Studies Using Apramycin in Feed tc Control Colibacillosis in Weaned Pigs. Vet. Med. 83(1):94-99; 1988.
12. Prescott, J.F.; Baggot, J.D.: Aminoglycosides and Aminocyclitols. Antimicrobial Therapy in Veterinary Medicine. Blackwell Scientific Publications, Boston, Mass., 1988; pp 140-141.
13. Nystrom, E.A.: Colibacillosis in Weaned Pigs. Proc. AASP, AASP, Des Moines, Iowa, 1994; pp 257-258.
14. Fairbrother, J.M.: Erteric Colibacillosis. Diseases of Swine, 7th Ed. (A.D. Leman et al, eds.). Iowa State University Press, Ames, 1992; pp 489-497.
15. Kyriakis, S.C.: The Effect of Avilamycin in the Control of Stress-induced Post-weaning Diarrhea in Piglets. J. Vet. Pharmacol. Ther. 12:296-301; 1989.
16. Jansen, W.A.H.: Comparison of the Effectiveness of Furazolidone and Apramycin in the Treatment of Colibacillosis in Weaned Pigs. Tijdschr. Diergeneeskd. 128:319-321; 1983.
17. Andreatis, J.S. et al: An Evaluation of Apramycin as an In-feed Medication for the Treatment of Postweaning Colibacillosis; in Pigs. Veterinary Res. Comm. 4:131-138; 1980.
18. Tacconi, G. et al: Evaluation of the Efficacy of Apramycin Against Salmonella pullorum Infection in Chickens. Avian Pathol. 16:319-326; 1987.
19. Cracknell, V.C. et al: An Evaluation of Apramycin Soluble Powder for the Treatment of Naturally Acquired Escherichia coli Infections in Broilers. J. Vet. Pharmacol. Ther. 9:273-279; 1986.
20. Upson, D.W.: Antimicrobial Drugs. Upson's Handbook of Clinical Veterinary Pharmacology, 2nd Ed. Veterinary Medicine Publishing Co., Lenexa, Kan., 1985; pp 618-619.
21. Freidlin, P.J. et al: Apramycin: Minimal Inhibitory Concentrations for Avian Escherichia coli and Serum Levels After Intramuscular Injection in Turkeys. J. Vet. Pharmacol. Ther. 8:105-109; 1985.
22. Lovering, A.M. et al: AAC(1): A New Aminoglycoside-acetylating Enzyme Modifying the C1 Amino Group of Apramycin. J. Antimicrob. Chemother. 20:803-813; 1987.
23. Hedges, R.W.; Shannon, K.P.: Resistance to Apramycin in Escherichia coli Isolated from Animals: Detection of a Novel Aminoglycoside Modifying Enzyme. J. Gen. Microbiol. 130:473-482; 1984.
24. Chaslus-Dancla, E. et al: Detection of Apramycin Resistant Enterobacteriaceae in Hospital Isolates. FEMS Microbiol. Lett. 61:261-265; 1989.
25. Gomez-Lus, R. et al: Resistance to Apramycin in Klebsiella pneumoniae Isolated from Patients: Detection of 3-N-acetyltransferase IV (Abst. 400). 27th Interscience Conf. Antimicrob. Agents Chemother., American Society for Microbiology, Washington, D.C., 1987; p 166.
26. Gomez-Lus, R. et al: Resistance to Apramycin in Two Enterobacterial Clinical Isolates: Detection of a 3-N-acetyl-transferase IV. J. Chemother. 2:241-243; 1990.
27. Chaslus-Dancla, E. et al: Emergence of Aminoglycoside 3-N-acetyltransferase IV in Escherichia coli and Salmonella typhimurium Isolated from Animals in France. Antimicrob. Agents Chemother. 29:239-243; 1986.
28. Threlfall, E.J. et al: Characterization of Plasmids Conferring Resistance to Gentamicin and Apramycin in Strains of Salmonella typhimurium Phage Type 204C Isolated in Britain. J. Hyg. 97:419-426; 1986.
29. Chaslus-Dancla, E. et al: Nucleic Acid Hybridization with a Probe Specific for 3 Aminoglycoside Acetyl-transferase Type IV: A Survey of Resistance to Apramycin and Gentamicin in Animal Strains of Escherichia coli. FEMS Microbiol. Lett. 34:265-268; 1986.
30. Chaslus-Dancla, E. et al: High Genetic Homology Between Plasmids of Human and Animal Origins Conferring Resistance to the Aminoglycosides Gentamicin and Apramycin. Antimicrob. Agents Chemother. 35:590-593; 1991.
31. Sojka, W.J. et al: Survey of Drug Resistance in Salmonellae Isolated from Animals in England and Wales from 1979 to 1981. Brit. Vet. J. 140:576-591; 1984.
32. Chaslus-Dancla, E.; Lafout, J.P.: Resistance to Gentamicin and Apramycin in Escherichia coli from Calves in France. Vet. Rec. 117:90-91; 1985.
33. Wray, C. et al: Apramycin and Gentamicin Resistance in Escherichia coli and Salmonella Isolated from Farm Animals. J. Hyg. 97:445-456; 1986.
34. Hunter, J.E.B. et al: Apramycin Resistance Plasmids in Escherichia coli: Possible Transfer to Salmonella typhimurium in Calves. Epidemiol. Infect. 108:271-278; 1992.
35. Hunter, J.E.B. et al: Apramycin-resistant E. coli Isolated from Pigs and a Stockman. Epidemiol. Infect. 112:473-480; 1994.
36. Pohl, P. et al: Replica Typing Characterization of Plasmids Encoding Resistance to Gentamicin and Apramycin in Escherichia coli and Salmonella typhimurium Isolated from Human and Animal Sources in Belgium. Epidemiol. Infect. Dis. 111:229-238; 1993.
37. Chengappa, M.M. et al: Prevalence of Salmonella in Raw Meat Used in Diets of Racing Greyhounds. J. Vet. Diagn. Invest. 5:372-377; 1993.
38. Hunter, J.E.B. et al: Human Isolates of Apramycin-resistant Escherichia coli Which Contain the Genes for the AAC(3) IV Enzyme. Epidemiol. Infect. 110:253-259; 1993.
39. Johnson, A.P. et al: Gentamicin Resistance in Clinical Isolates of Escherichia coli Encoded by Genes of Veterinary Origin. J. Med. Microbiol. 40:221-226; 1994.
40. Salauze, D., et al: Aminoglycoside Acetyltransferase 3-IV (aacC4) and Hygromycin B + 1 Phosphotransferase (hphB) in Bacteria Isolated from Human and Animal Sources. Antimicrob. Agents Chemother. 34:1915-1920; 1990.
41. London, N. et al: Carriage of Antibiotic-resistant Escherichia coli by Healthy Volunteers During a 15-week Period. Infection 22:187-192; 1994.