Reactions of pyrimidinonethione derivatives: Synthesis of 2-hydrazinopyrimidin-4-one, pyrimido[1,2-a]-1,2,4-triazine, triazolo-[1,2-a]pyrimidine, 2-(1-pyrazolo)pyrimidine and 2-arylhydrazonopyrimidine derivatives

Archives of Pharmacal Research

Volumn 20, Issue 6, 1997, Pages 620-628

  Attaby, Fawzy A ^a   Eldin, Sanaa M ^b   Hanafi, Eman A Z ^c  

^a CAIRO UNIVERSITY   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

^c NONE

Author keywords

Pyrimidinethione; Pyrimidotriazine; Triazolopyrimidine and cinnamonitrile

Indexed keywords

EID: 0007290457     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02975221     Document Type: Article

References (9)

1. Ieven M., Vlietinck A. J., Vanden Berghe D. A., Totte J., Domisse R., Esmans E. and Alderweireldt E., Plant antiviral agents; isolation of alkaloids from clivia miniata regle (Amaryllidaceae). J. Nat. Prod, 45, 564 (1982).
2. Kambe S., Saito K., Kishi H., Sakurai A. and H. Midorikawa, A one-step synthesis of 4-Oxo-2-thioxopyrimidine derivatives by the ternary condensation of ethyl cyanoacetate, aldhydes and thiourea. Synthesis, 4, 287 (1979).
3. Koksharova T. G., Volkova N. V., Dianova L. V., Tlenko V. I., Platonov V. G. and Shchervbakova I. R., Khim. Farm. Zh., 27, 57 (1992).
4. Ram V. J.; Chemotherapeutic agents XVIII: Synthesis of π-deficient pyrimidines and fused pyrimidines as leishmanicidal agents. Arch. Pharm., 323, 895 (1990).
5. Ram V. J., Hague N. and Guru P. Y.; Chemotherapeutic agents XXV: Synthesis and leishmanicidal activity of carbazolylpyrimidines. Eur. J. Med. Chem., 27, 851 (1992).
6. Ram V. J., Vanden Berghe D. A. and Vlietinck A. J.; Synthesis and activities of novel pyrimidines derived from 5-cyano-6-aryl-2-thiouracil. Liebigs Ann. Chem., 9, 797 (1987).
7. Ram V. J., Vanden Berghe D. A. and A. J. Vlietinck; 5-Cyano-6-aryluracil and 2-thiouracil derivatives as potential chemotherapeutic agents. J. Het. Chem., 21, 1307 (1984).
8. Vanden Berghe D. A., Ieven M., Mertens F., Vlietinck A. J. and Lammens E., Screening of higher plants for biological activities, antiviral activity. Lloydia, 41, 463 (1978).
9. Vanden Berghe D. A., Vlietinck A. J. and Van Hoof L.; Plant products as potential antiviral agents. Bull. Inst. Pasteur, 84, 101 (1986).