Is platelet phospholipid-dependent thrombin generation altered by acute myocardial infarction or aspirin?

Thrombosis Research

Volumn 83, Issue 4, 1996, Pages 329-338

  Rota, Simin ^a   Flynn, Paul D ^b   Wareham, Nicholas J ^c   Baglin, Trevor P ^d   Byrne, Christopher D ^a,e  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Aspirin; Myocardial infarction; Platelet phospholipid dependent thrombin generation

Indexed keywords

ACETYLSALICYLIC ACID; CITRATE SODIUM; EDETIC ACID; PHOSPHOLIPID; THROMBIN;

ACUTE HEART INFARCTION; ADULT; AGE; AGED; ARTICLE; CONTROLLED STUDY; HUMAN; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE ACTIVATION;

EID: 0006665003     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/0049-3848(96)00141-7     Document Type: Article

References (23)

1. BEVERS E.M., COMFURIUS P., ZWAAL R.F.A. Platelet procoagulant activity: Physiological significance and mechanisms of exposure. Blood Reviews. 5:1991;146-154.
2. BENDER J.R., SADEGHI M.M.M., MILLS L.K.et al. Endothelial cell adhesion molecule induction by alpha-thrombin. J Cell Biochem. 16A:1992;202.
3. HARLAN J.M., THOMPSON P.J., ROSS R., BOWEN-POPE D.F. Alpha-thrombin induces release of platelet-derived growth factor-like molecules by cultured human endothelial cells. J Cell Biol. 103:1986;1129-1133.
4. LEVIN E.G., MARZEC U., ANDERSON J., HARKER L.A. Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells. J Clin Invest. 74:1984;1988-1995.
5. GELEHRTER T.D., SZNYCER-LASZUK R. Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells. J Clin Invest. 77:1986;165-169.
6. WEKSLER B.B., LEY C.W., JAFFE E.A. Stimulation of endothelial cell prostacyclin production by thrombin, trypsin and inophore A23187. J Clin Invest. 62:1978;923-930.
7. PRESCOTT S.M., ZIMMERMAN G.A., MCINTYRE T.M. Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocoline) when stimulated with thrombin. Proc Natl Acad Sci USA. 81:1984;3534-3538.
8. BAR-SHAVIT R., KAHN A., WILNER G.D., FENTON J.W. II Monocyte chemotaxis: Stimulation by specific exosite region in thrombin. Science. 220:1983;728-731.
9. MCNAMARA C.A., SAREMBOCK I.J., GIMPLE L.W., FENTON J.W. II, COUGHLIN S.R., OWENS G.K. Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor. J Clin Invest. 91:1993;94-98.
10. GLENN K.C., CARNEY D.H., FENTON J.W. II, CUNNINGHAM D.D. Thrombin active site regions for fibroblast receptor binding and initiation of cell division. J Biol Chem. 255:1980;6609-6616.
11. Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction : ISIS-2. J American College Cardiol 12, 3A-13A, 1988.
12. PATRONO C. Aspirin as an antiplatelet drug. N Eng J Med. 330:1994;1287-1294.
13. HEMKER H.C., BEGUIN S. Thrombin Generation in plasma: Its assessment via the endogenous thrombin potential. Thromb Haemost. 74:1995;134-138.
14. LEE L.H., BAGLIN T. Altered platelet phospholipid-dependent thrombin generation in thrombocytopenia and thrombocytosis. Brit J Haem. 89:1995;131-136.
15. REARDON, D.M., WARNER, B., TROWBRIDGE, E.A. EDTA, the traditional anticoagulant of haematology: with increased automation is it time for a review? Medical Laboratory Sciences 48: 72-5, 1991.
16. BYRNE C.D, WAREHAM N.J., BROWN D.C., CLARK P.M.S., COX L.J., DAY N.E., PALMER C.R., WANG T.W.M., WILLIAMS D.R.R., HALES C.N. Hypertriglyceridaemia in subjects with normal and abnormal glucose tolerence:Relative contributions of insulin secretion, insulin resistance and suppression of plasma non-esterified fatty acids. Diabetalogia. 37:1994;889-896.
17. LUDDINGTON R., BROWN K., BAGLIN T. Effect of platelet phospholipid exposure on activated protein C resistance: Implications for thrombophilia screening. Brit J Haem. 92:1996;744-746.
18. BLAND, J.M., ALTMAN, D.G. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet i: 307-310, 1986.
19. VU T.K.H., HUNG D.T., WHEATON V.I., COUGHLIN S.R. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 64:1991;1057-1068.
20. SZCZEKLIK A., DROPINSKI J., RADWAN J., KRZANOWSKI M. Persistent generation of thrombin after acute myocardial infarction. Arterioscler Thromb. 12:1992;548-553.
21. SZCZEKLIK A., KRZANOWSKI M., GORA P., RADWAN J. Antiplatelet drugs and generation of thrombin in clotting blood. Blood. 80:1992;2006-2011.
22. KESSELS H., BEGUIN S., ANDREE H., HEMKER H.C. Measurement of thrombin generation in whole blood-The effect of heparin and aspirin. Thromb Haem. 72:1994;78-83.
23. ARONSON D.L., CHANG P., KESSLER C.M. Platelet-dependent thrombin generation after in vitro fibrinolytic treatment. Circulation. 85:1992;1706-1712.