Automated Analysis of Feline Platelets in Whole Blood, Including Platelet Count, Mean Platelet Volume, and Activation State

Veterinary Clinical Pathology

Volumn 27, Issue 1, 1998, Pages 2-9

  Zelmanovic, David ^a   Hetherington, Edward J ^a  

^a BAYER CORPORATION   (United States)

Author keywords

Activation state; Feline; MPV; Platelet counts; Whole blood

Indexed keywords

FELIDAE; FELIS CATUS; MOROCCAN PEPPER VIRUS;

EID: 0006547231     PISSN: 02756382     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1939-165X.1998.tb01071.x     Document Type: Article

References (31)

1. Barer R, Joseph S: Refractometry of living cells. Quart J Microscopic Sci 95:399-423, 1953
2. van Oost B, van Hien-Hagg IH, Timmermans APM, et al: The effect of thrombin on the density distribution of blood platelets: detection of activated platelets in the circulation. Blood 62:433-438, 1983
3. Pennington DG, Lee NLY, Roxburgh AE, et al: Platelet density and size: the interpretation of heterogeneity. Br J Hematol 34:365-376, 1976
4. Corash L, Tan H, Gralnick JR, et al: Heterogeneity of human whole blood subpopulations. I. Relationship between buoyant density, cell volume and ultrastructure. Blood 49:71-85, 1977
5. Friedhoff AJ, Miller JC, Karpatkin S: Heterogeneity of human platelets. VII. Platelet monoamine oxidase activity in normals and patients with autoimmune thrombocytopenic purpura and reactive thrombocytosis: its relationship to platelet protein density. Blood 51:317-323, 1978
6. Thompson CB, Eaton KA, Princiotta SM, et al: Size dependent platelet subpopulations: relationship of platelet volume to ultrastructure, enzymatic activity, and function. Br J Haematol 50: 509-519, 1982
7. Corash L, Costa JL, Shafer B, et al: Heterogeneity of human whole blood platelet subpopulations. III: Density-dependent differences in subcellular constituents. Blood 64:185-193, 1984
8. Paulus JM: Platelet size in man. Blood 46:321-336, 1975
9. Zucker MB, Borrelli J. Reversible alterations in platelet morphology produced by anticoagulants and by cold. Blood 9:602-608, 1954
10. Bull BS, Zucker MB: Changes in platelet volume produced by temperature, metabolic inhibitors and aggregating agents. Proc Soc Exp Biol Med 120:296-301, 1965
11. Holme S, Murphy S: Coulter counter and light transmission studies of platelets exposed to low temperature, ADP, EDTA, and storage at 22°C. J Lab Clin Med 96:480-493, 1980
12. Ross DW, Bentley SA: Evaluation of an automated hematology system (Technicon H-1). Arch Path Lab Med 110:803-808, 1986
13. Warner BA, Reardon DM, Marshall DP: Automated haematology analysers: a four-way comparison. Med Lab Sci 47:285-296, 1990
14. Martin JF, Shaw T, Heggie J, et al: Measurement of the density of human platelets and its relationship to volume. Br J Hematol 54:337-352, 1983
15. Penington DG, Lee NLY, Roxburgh AE, and McGready JR. Platelet density and size: the interpretation of heterogeneity. Br J Haematol 34:365-376, 1976
16. Frojmovic MM and Milton JG: Human platelet size, shape, and related functions in health and disease. Phys Rev 62:185-261, 1982
17. Holme S, Simmonds M, Ballek R, et al: Comparative measurements of platelet size by Coulter Counter, microscopy of blood smears, and light-transmission studies. Relationship between platelet size and shape. J Lab Clin Med 97:610-622, 1981
18. Holme S, Heaton A, Konchuba A, et al: Light scatter and total protein signal distribution of platelets by flow cytometry as parameters of size. J Lab Clin Med 112:223-31, 1988
19. Holme S, Bode A, Heaton WAL, et al: Improved maintenance of platelet in vivo viability during storage when using a synthetic medium with inhibitors. J Lab Clin Med 119:144-150, 1992
20. Zeigler Z, Murphy S, Gardner FH: Microscopic platelet size and morphology in various hematologic disorders. Blood 51: 479-486, 1978
21. Watson HHK, Ludlam CA: Survival of 111-indium platelet subpopulations of varying density in normal and post splenectomized subjects. Br J Hematol 62:117-124, 1986
22. Shattil SJ, Cunningham M, Hoxie JA: Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry. Blood 70; 307-15, 1987
23. Abrams CS, Ellison N, Budzynski AZ, Shattil SJ: Direct detection of activated platelets and platelet-derived microparticles in humans. Blood 75; 128-38, 1990
24. Corash L: Measurement of platelet activation by fluorescence activated flow cytometry. Blood Cells 16:97-108, 1990
25. Michelson AD: Platelet activation by thrombin can be directly measured in whole blood through the use of the peptide GPRP and flow cytometry: methods and clinical applications. Blood Coag Fibrinolysis 5:121-31, 1994
26. Welles EG, Bourne C, Tyler JW, Boudreaux MK: Detection of activated feline platelets in platelet-rich plasma by use of fluorescein-labeled antibodies and flow cytometry. Vet Pathol 31:553-560, 1994
27. Chapman ES, Hetherington EJ, Zelmanovic D: A simple automated method for determining ex-vivo platelet activation state. Blood 88: 2929, 1996
28. Trowbridge EA, Reardon DM, Hutchinson D, Pickering C: The routine measurement of platelet volume: a comparison of light scattering and aperture impedance technologies. Clin Phys Physiol Meas 6:221-238, 1985
29. Thompson CB, Diaz DD, Quinn PG, et al. The role of anticoagulation in the measurement of platelet volumes. Ann J Clin Path 80:327-332, 1983
30. Corash L: Platelet sizing: techniques, biological significance and clinical applications. Curr Topics Hematol 4:99-122, 1983
31. Threatte GA: Usefulness of the mean platelet volume. Clin Lab Med 13: 937-950, 1993