Controlled dissolution of phenytoin by hybridizing with silica nanoparticles

Journal of Nanoparticle Research

Volumn 1, Issue 2, 1999, Pages 205-213

  Goto, H ^a   Isobe, T ^a   Senna, M ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

Dissolution rate; Hydrogen bond; Phenytoin; Silica drug hybrids; Sol gel process; Sparingly soluble drug

Indexed keywords

EID: 0006041969     PISSN: 13880764     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010048332458     Document Type: Article

References (9)

1. Borchard G., K.L. Audus, F. Shi & J. Kreuter, 1994. Int. J. Pharm. 110, 29.
2. Chujo Y., H. Matsuki, S. Kure & T. Saegusa, 1994. J. Chem. Soc. Chem. Commun. 635.
3. Elliott T.H. & P.M. Natarajan, 1967. J. Pharm. Pharmac. 19, 209.
4. Goto H., T. Isobe & M. Senna, 1998. In: Gonsalves K.E., Baraton M.I., Hofmann H, Singh R., Chen J.X. & Akkara J.A. eds. Paniculate Coatings: Synthesis and Processing, Mat. Res. Soc. Symp. Proc., Pittsburgh, PA, Vol. 501, 321 pp.
5. Kaneniwa N. & M. Otsuka, 1985. Chem. Pharm. Bull. 33(4), 1660.
6. Muller R.H., W. Mehnert, J.S. Lucks, C. Schwarz et al., 1995. J. Pharm. Biopharm. 41, 62.
7. Saegusa T. & Y. Chujo, 1991. Macromol. Chem., Macromol. Symp. 51, 1.
8. Zipp G.L. & N. Rodriguez-Hornedo, 1993. J. Phys. D, Appl. Phys. 26, B48.
9. Zipp G.L. & N. Rodriguez-Hornedo, 1992. J. Crys. Growth. 123, 247.