Nanoscalpels: Immunotherapy for cancer. Attacking deadly micrometastatic tumor cells

Modern Drug Discovery

Volumn 3, Issue 3, 2000, Pages 37-42

  Baeuerle, Patrick A ^a   Wolf, Evelyn ^a  

^a NONE

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EID: 0005632062     PISSN: 10998209     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

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2. Riethmüller, G., et al. Monoclonal antibody therapy for resected Dukes' C colorectal cancer: Seven-year outcome of a multicenter randomized trial. J. Clin. Oncol. 1998, 16, 1788-1794.
3. Löffler, A., et al. A recombinant bispecific single chain antibody CD19xCD3 induces rapid and high lymphoma directed T cell cytotoxicity. Blood 2000, in press.
4. Müller, P., et al. Detection of Genetic Alterations in Micrometastatic Cells in Bone Marrow of Cancer Patients by Fluorescence In Situ Hybridization Cancer Genet. Cytogenet. 1996, 88, 8-16.
5. Klein, Ch. A., et al. Comparative genomic hybridization, loss of heterozygosity and DNA sequence analysis of single cells. Proc. Natl. Acad. Sci. USA 1999, 96, 4494-4499.
6. Pinkel, D., et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nature Genet. 1998, 20, 207-211.
7. Schlimok, G., et al. Reduction of Metastatic Carcinoma Cells in Bone Marrow by Intravenously Administered Monoclonal Antibody: Towards a Novel Surrogate Test to Monitor Adjuvant Therapies of Solid Tumors. European J. Cancer 1995, 31A, 1799-1803.
8. Kvalheim, G., et al. Minimal residual disease in breast cancer. Cancer Metastasis Rev. 1999, 18 (1), 101-108.