Ochratoxin a induced TNFα release from the isolated and blood - Free perfused rat liver

Mycotoxin Research

Volumn 16, Issue 2 SUPPL., 2000, Pages 189-193

  Weidenbach, A ^a   Schuh, K ^a   Failing, K ^a   Petzinger, E ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0005322573     PISSN: 01787888     EISSN: 18671632     Source Type: Journal    
DOI: 10.1007/BF02940035     Document Type: Article

References (15)

1. Hesseltine CW, Vandegraft EE, Fennell D.I., Smith ML and Shotwell OL (1972) Aspergilli as Ochratoxin producers. Mycologia. 64: 539-550
2. Ciegler A, Fennell DI, Sansing G.A., Detroy RW and Bennett GA (1973) Mycotoxin-producing strains of Pénicillium viridicatum: Classification into subgroupps. Appl Microbiol. 26: 217-280
3. Pitt JL (1987) Penicillium viridicatum, Penicillium verricisum and production of Ochratoxin A. Appl. Environ. Microbiol. 53(2): 266-269
4. Singh GS. (1990) Immunosupression due to chronic ochratoxicosis in broiler chicks. J. Comp. Pathol. 103:417-419
5. Kontaxi M, Eckhardt U, Hagenbuch B., Stieger B, Meier PJ and Petzinger E, et al. (1996) Uptake of the mycotoxin ochratoxin A in liver cells occurs via the cloned organic anion transporting polypeptide. J. Pharmacol. Exp. Ther. 279: 1507-15013
6. Atroshi F, Rizzo A, Sankari S., Biese I, Westermarck T and Veijalainen P (2000) Liver enzyme activities of rats exposed to ochratoxin A and T-2 toxin with antioxidants. Bull Environ Contam Toxicol. Apr. 64(4): 586-92
7. Boormann G (1989) Technical Report on the Toxicology and Carcinogenesis Studies of Ochratoxin A (CAS No 303-47-9) in F344/N Rats (Gavage studies). NTP TR 358, NM Publication no 89-2813. Ed. G. Boormann. U.S. Department of Health and Human Services. National Institute of health, research Triangle Park, NC.
8. Heinrich PC The acute-phase response of the liver: molecular mechanisms of IL-6 signalling fromthe plasma membrane to the nucleus. IN: Signalling in the liver, Inenational Falk Workshop, Edited by D. Häussinger and P.C. Heinrich: pp. 55-71
9. Debets JM, Kampmeijer R, van der Linden MP, Buurman WA, van der Linden CJ (1989) Plasma tumor necrosis factor and mortality in critically ill septic patients. Crit. Care Med. 17:489-494
10. Vassalli, P. (1992) The pathophysiology of Tumor necrosis factors. Annu. Rev. Immunol. 10:411-52
11. Decker, K. (1990) Biologically active products of stimulated liver macrophages (Kupffer cells). Eur. J. Biochem. 192: 245-267
12. Diehl, AM, Yin M, Fleckenstein J., Yang SQ, Lin HZ, Brenner DA, Westwick J, Bagby G., Nelson S. (1994) Tumor necrosis factor alpha induces c-jun during th eregenerative response to liver injury. Am. J. Physiol. 267: G552-561
13. Cornelius P, Marlowe M, Lee M.D., Pekala P.H. (1990) The growth factor like effects of tumor necrosis factor alpha. J. Biol. Chem. 265: 2056-2061
14. Collard MA et al. (1990) Regulation of tumor necrosis factor-alpha transcription in macrophages: involvement of four KB like motifs and constitutive and inducible forms of NFκB. Mol. Cell. Biol. 10: 1498-1506
15. Shakohov AN, et al (1990) Kappa B type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages. J. Exp. Med. 171: 35-47