메뉴 건너뛰기




Volumn 265, Issue 2, 1999, Pages 671-679

Advantages and disadvantages of aggregating fluxes into synthetic and degradative fluxes when modelling metabolic pathways

Author keywords

Biochemical systems theory; Flux aggregation; Kinetic models; Metabolic control analysis; Metabolism

Indexed keywords

ARTICLE; CALCULATION; METABOLISM; MODEL; NONHUMAN; PRIORITY JOURNAL; STOICHIOMETRY; THEORY;

EID: 0005272597     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00760.x     Document Type: Article
Times cited : (10)

References (34)
  • 1
    • 0014649230 scopus 로고
    • Biochemical systems analysis. 1. Some mathematical properties of the rate laws for the component enzymatic reactions
    • 1. Savageau, M.A. (1969) Biochemical systems analysis. 1. Some mathematical properties of the rate laws for the component enzymatic reactions. J. Theor. Biol. 25, 365-369.
    • (1969) J. Theor. Biol. , vol.25 , pp. 365-369
    • Savageau, M.A.1
  • 2
    • 0014658880 scopus 로고
    • Biochemical systems analysis. 2. The steady-state solutions for an n-pool system using a power-law approximation
    • 2. Savageau, M.A. (1969) Biochemical systems analysis. 2. The steady-state solutions for an n-pool system using a power-law approximation. J. Theor. Biol. 25, 370-379.
    • (1969) J. Theor. Biol. , vol.25 , pp. 370-379
    • Savageau, M.A.1
  • 7
    • 0024673592 scopus 로고
    • Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. I. Unbranched pathways
    • 7. Cascante, M., Franco, R. & Canela, E.I. (1989) Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. I. Unbranched pathways. Math. Biosci. 94, 271-288.
    • (1989) Math. Biosci. , vol.94 , pp. 271-288
    • Cascante, M.1    Franco, R.2    Canela, E.I.3
  • 8
    • 0024673575 scopus 로고
    • Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. II. Complex systems
    • 8. Cascante, M., Franco, R. & Canela, E.I. (1989) Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. II. Complex systems. Math. Biosci. 94, 289-309.
    • (1989) Math. Biosci. , vol.94 , pp. 289-309
    • Cascante, M.1    Franco, R.2    Canela, E.I.3
  • 9
    • 0024673614 scopus 로고
    • A comparison of variant theories of intact biochemical systems. I. Enzyme-enzyme interactions and biochemical systems theory
    • 9. Sorribas, A. & Savageau, M.A. (1989) A comparison of variant theories of intact biochemical systems. I. Enzyme-enzyme interactions and biochemical systems theory. Math. Biosci. 94, 161-193.
    • (1989) Math. Biosci. , vol.94 , pp. 161-193
    • Sorribas, A.1    Savageau, M.A.2
  • 10
    • 0024673624 scopus 로고
    • A comparison of variant theories of intact biochemical systems. II. Flux-oriented and metabolic control theories
    • 10. Sorribas, A. & Savageau, M.A. (1989) A comparison of variant theories of intact biochemical systems. II. Flux-oriented and metabolic control theories. Math. Biosci. 94, 195-238.
    • (1989) Math. Biosci. , vol.94 , pp. 195-238
    • Sorribas, A.1    Savageau, M.A.2
  • 11
    • 0023661067 scopus 로고
    • Accuracy of alternative representations for integral biochemical systems
    • 11. Voit, E.O. & Savageau, M.A. (1987) Accuracy of alternative representations for integral biochemical systems. Biochemistry 26, 6869-6880.
    • (1987) Biochemistry , vol.26 , pp. 6869-6880
    • Voit, E.O.1    Savageau, M.A.2
  • 12
    • 0027989263 scopus 로고
    • The tricarboxylic acid cycle in Dictyostelium discoideum. Two methods of analysis using the same data
    • 12. Wright, B.E. & Field, R.J. (1994) The tricarboxylic acid cycle in Dictyostelium discoideum. Two methods of analysis using the same data. J. Biol. Chem. 269, 19931-19932.
    • (1994) J. Biol. Chem. , vol.269 , pp. 19931-19932
    • Wright, B.E.1    Field, R.J.2
  • 13
    • 0031832789 scopus 로고    scopus 로고
    • Mathematical models of purine metabolism in man
    • 13. Curto, R., Voit, E.O., Sorribas, A. & Cascante, M. (1998) Mathematical models of purine metabolism in man. Math. Biosci. 151, 1-49.
    • (1998) Math. Biosci. , vol.151 , pp. 1-49
    • Curto, R.1    Voit, E.O.2    Sorribas, A.3    Cascante, M.4
  • 14
    • 0009678781 scopus 로고
    • A modular approach to the description of the control of connected metabolic systems
    • Schuster, S., Rigoulet, M., Ouhabi, R. & Mazat, J.-P., eds, Plenum Press, New York and London
    • 14. Schuster, S., Kahn, D. & Westerhoff, H.V. (1993) A modular approach to the description of the control of connected metabolic systems. In Modern Trends in Biothermokinetics (Schuster, S., Rigoulet, M., Ouhabi, R. & Mazat, J.-P., eds), pp. 229-235. Plenum Press, New York and London.
    • (1993) Modern Trends in Biothermokinetics , pp. 229-235
    • Schuster, S.1    Kahn, D.2    Westerhoff, H.V.3
  • 15
    • 0027486853 scopus 로고
    • Modular analysis of the control of complex metabolic pathways
    • 15. Schuster, S., Kahn, D. & Westerhoff, H.V. (1993) Modular analysis of the control of complex metabolic pathways. Biophys. Chem. 48, 1-17.
    • (1993) Biophys. Chem. , vol.48 , pp. 1-17
    • Schuster, S.1    Kahn, D.2    Westerhoff, H.V.3
  • 16
    • 0025238865 scopus 로고
    • A "top-down" approach to the determination of control coefficients in metabolic control theory
    • 16. Brown, G.C., Hafner, R.P. & Brand, M.D. (1990) A "top-down" approach to the determination of control coefficients in metabolic control theory. Eur. J. Biochem. 188, 321-325.
    • (1990) Eur. J. Biochem. , vol.188 , pp. 321-325
    • Brown, G.C.1    Hafner, R.P.2    Brand, M.D.3
  • 17
    • 0023385129 scopus 로고
    • Matrix method for determining steps most rate-limiting to metabolic fluxes in biotechnological processes
    • 17. Westerhoff, H.V. & Kell, D.B. (1987) Matrix method for determining steps most rate-limiting to metabolic fluxes in biotechnological processes. Biotechnol. Bioeng. 30, 101-107.
    • (1987) Biotechnol. Bioeng. , vol.30 , pp. 101-107
    • Westerhoff, H.V.1    Kell, D.B.2
  • 19
    • 0021360023 scopus 로고
    • Modern theories of metabolic control and their applications
    • 19. Westerhoff, H.V., Groen, A.K. & Wanders, J.A. (1984) Modern theories of metabolic control and their applications. Biosci. Report 4, 1-22.
    • (1984) Biosci. Report , vol.4 , pp. 1-22
    • Westerhoff, H.V.1    Groen, A.K.2    Wanders, J.A.3
  • 21
    • 0031554875 scopus 로고    scopus 로고
    • An indirect optimization method for biochemical systems: Description of method and application to the maximization of the rate of ethanol, glycerol, and carbohydrate production in Saccharomyces cerevisiae
    • 21. Torres, N., Voit, E.O., González-Alcón, C. & Rodríguez, F. (1997) An indirect optimization method for biochemical systems: description of method and application to the maximization of the rate of ethanol, glycerol, and carbohydrate production in Saccharomyces cerevisiae. Biotechnol. Bioeng. 55, 758-772.
    • (1997) Biotechnol. Bioeng. , vol.55 , pp. 758-772
    • Torres, N.1    Voit, E.O.2    González-Alcón, C.3    Rodríguez, F.4
  • 22
    • 0009675146 scopus 로고
    • ESSYNS: Evaluation and simulation of SYNergistic Systems
    • Cornish-Bowden, A. & Cárdenas, M.L., eds, Plenum Press, New York
    • 22. Irvine, D.H., Savageau, M.A. & Voit, E.O. (1990) ESSYNS: Evaluation and simulation of SYNergistic Systems. In Control of Metabolic Processes (Cornish-Bowden, A. & Cárdenas, M.L., eds), pp. 433-434. Plenum Press, New York.
    • (1990) Control of Metabolic Processes , pp. 433-434
    • Irvine, D.H.1    Savageau, M.A.2    Voit, E.O.3
  • 23
    • 0026023024 scopus 로고
    • MetaModel: A program for modelling and control analysis of metabolic pathways on the IBM PC and compatibles
    • 23. Cornish-Bowden, A. & Hofmeyr, J.-H.S. (1991) MetaModel: a program for modelling and control analysis of metabolic pathways on the IBM PC and compatibles. Comput. Appl. Biosci. 7, 89-93.
    • (1991) Comput. Appl. Biosci. , vol.7 , pp. 89-93
    • Cornish-Bowden, A.1    Hofmeyr, J.-H.S.2
  • 24
    • 0025769469 scopus 로고
    • CONTROL: Software for the analysis of the control of metabolic networks
    • 24. Letellier, T., Reder, C. & Mazat, J.-P. (1991) CONTROL: software for the analysis of the control of metabolic networks. Comp. Appl. Biosci. 7, 383-390.
    • (1991) Comp. Appl. Biosci. , vol.7 , pp. 383-390
    • Letellier, T.1    Reder, C.2    Mazat, J.-P.3
  • 25
    • 0027370376 scopus 로고
    • GEPASI: A software package for modelling the dynamics, steady states and control of biochemical and other systems
    • 25. Mendes, P. (1993) GEPASI: a software package for modelling the dynamics, steady states and control of biochemical and other systems. Comput. Appl. Biosci. 9, 563-571.
    • (1993) Comput. Appl. Biosci. , vol.9 , pp. 563-571
    • Mendes, P.1
  • 26
    • 0027178664 scopus 로고
    • SCAMP: A general-purpose simulator and metabolic control analysis program
    • 26. Sauro, H.M. (1993) SCAMP: a general-purpose simulator and metabolic control analysis program. Comput. Applic. Biosci. 9, 441-450.
    • (1993) Comput. Applic. Biosci. , vol.9 , pp. 441-450
    • Sauro, H.M.1
  • 27
    • 0027213450 scopus 로고
    • A computer program for the algebraic determination of control coefficients in metabolic control analysis
    • 27. Thomas, S. & Fell, D.A. (1993) A computer program for the algebraic determination of control coefficients in metabolic control analysis. Biochem. J. 292, 351-360.
    • (1993) Biochem. J. , vol.292 , pp. 351-360
    • Thomas, S.1    Fell, D.A.2
  • 28
    • 0024473068 scopus 로고
    • Metabolic control theory and biochemical systems theory: Different objectives, different assumptions, different results
    • 28. Cornish-Bowden, A. (1989) Metabolic control theory and biochemical systems theory: different objectives, different assumptions, different results. J. Theor. Biol. 136, 365-377.
    • (1989) J. Theor. Biol. , vol.136 , pp. 365-377
    • Cornish-Bowden, A.1
  • 29
    • 0001799180 scopus 로고
    • The nature and role of theory in metabolic control
    • Cornish-Bowden, A. & Cárdenas, M.L., eds, Plenum Press, New York
    • 29. Cornish-Bowden, A. (1990) The nature and role of theory in metabolic control. In Control of Metabolic Processes (Cornish-Bowden, A. & Cárdenas, M.L., eds), pp. 31-40. Plenum Press, New York.
    • (1990) Control of Metabolic Processes , pp. 31-40
    • Cornish-Bowden, A.1
  • 30
    • 0024293967 scopus 로고
    • Control analysis of biochemical pathways
    • 30. Giersch, C. (1988) Control analysis of biochemical pathways. J. Theor. Biol. 134, 451-462.
    • (1988) J. Theor. Biol. , vol.134 , pp. 451-462
    • Giersch, C.1
  • 31
    • 0023709196 scopus 로고
    • Metabolic control theory: A structural approach
    • 31. Reder, C. (1988) Metabolic control theory: a structural approach. J. Theor. Biol. 135, 175-201.
    • (1988) J. Theor. Biol. , vol.135 , pp. 175-201
    • Reder, C.1
  • 32
    • 0023219804 scopus 로고
    • Metabolic control and its analysis. Extensions to the theory and matrix analysis
    • 32. Sauro, H.M., Small, J.R. & Fell, D.A. (1987) Metabolic control and its analysis. Extensions to the theory and matrix analysis. Eur. J. Biochem. 165, 215-221.
    • (1987) Eur. J. Biochem. , vol.165 , pp. 215-221
    • Sauro, H.M.1    Small, J.R.2    Fell, D.A.3
  • 33
    • 0015103748 scopus 로고
    • Concepts relating the behaviour of biochemical systems to their underlying molecular properties
    • 33. Savageau, M.A. (1971) Concepts relating the behaviour of biochemical systems to their underlying molecular properties. Arch. Biochem. Biophys. 145, 612-621.
    • (1971) Arch. Biochem. Biophys. , vol.145 , pp. 612-621
    • Savageau, M.A.1
  • 34
    • 0024442732 scopus 로고
    • Constraints among molecular and systemic properties: Implications for physiological genetics
    • 34. Savageau, M.A. & Sorribas, A. (1989) Constraints among molecular and systemic properties: implications for physiological genetics. J. Theor. Biol. 141, 93-115.
    • (1989) J. Theor. Biol. , vol.141 , pp. 93-115
    • Savageau, M.A.1    Sorribas, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.