Systemic effects of topical and subconjunctival ophthalmic atropine in the horse

Veterinary Ophthalmology

Volumn 3, Issue 2-3, 2000, Pages 193-199

  Williams, Melanie M ^a   Spiess, Bernhard M ^b   Pascoe, Peter J ^c   O'Grady, Michael ^d  

^a Toronto Yorke   (Canada)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF GUELPH   (Canada)

Author keywords

Colic; Horse; Ophthalmic atropine sulfate; Systemic side effects

Indexed keywords

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 0005107641     PISSN: 14635216     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1463-5224.2000.00118.x     Document Type: Article

References (24)

1. Muir WW. The effects of atropine on cardiac rate and rhythm in dogs. Journal of the American Veterinary Medical Association, 1977; 172: 917-921.
2. Wu D, Denes P, Bauernfeind R, Dhingra RC, Wyndham C, Rosen KM. Effects of atropine on induction and maintenance of atrioventricular nodal reentrant tachycardia. Circulation, 1979; 59: 779-788.
3. Merli GJ, Weite H, Martin JH, McClay EF, Adler AG, Fellin FM, Libonati M. Cardiac dysrhythmias associated with ophthalmic atropine. Archives Internal Medicine, 1986; 146: 45-47.
4. Ducharme NG, Fubini SI. Gastrointestinal complications associated with the use of atropine in horses. Journal of the American Veterinary Medical Association, 1983; 187: 229-231.
5. Adams SB, Lamar CH, Marty J. Motility of the distal portion of the jejunum and pelvic flexure in ponies. Effects of six drugs. American Journal of Veterinary Research, 1984; 45: 795-799.
6. McLaughlin S, Whitley RD, Gilger BC. Ophthalmic atropine in horses: Is colic a serious problem? Equine Veterinary Education, 1991; 3: 94-96.
7. Zekas LJ, Lester G, Brooks DE. The effect of ophthalmic atropine on intestinal transit and myoelectric activity in normal adult horses. Proceedings of the American College of Veterinary Ophthalmologists Annual Meeting, Seattle, WA. October 21-24, 1998.
8. Kachmer McGregor ML. Autonomic Drugs. In: Havener's Ocular Pharmacology, 6th edn. (eds. Mauger TF, Craig EL) The CV Mosby Co., St. Louis, 1994: 140-146.
9. Innes IR, Nickerson M. Atropine, scopolamine, and related antimuscarinic drugs. In: The Pharmacological Basis of Therapeutics. (eds Goodman LS, Gilman A) 5th edn. MacMillan Publishing Co, Inc., New York, 1975: 257-263.
10. Ludders J, Heavner JE. Effect of atropine on tear formation in anaesthetized dogs. Journal of the American Veterinary Medical Association, 1979; 175: 585-586.
11. Gwin RM. Pharmacological agents that reduce intraocular pressure. In: Veterinary Ophthalmology. (ed. Gelatt KN) Lea and Febiger, Philadelphia, 1981: 197-200.
12. Jones RG, Stiles JF. The penetration of C14 labeled atropine into the eye. Archives of Ophthalmology, 1959; 62: 69.
13. Van Alphen GWHM, Macri FJ. Entrance of fluoresceine into aqueous humor of cat eye. Archives of Ophthalmology, 1966; 75: 247-253.
14. Kantelip JP, Alatienne M, Gueorguiev G, Duchene-Marullaz P. Chronotropic and dromotropic effects of atropine and hyoscine methobromide in unanaesthetized dogs. British Journal of Anaesthesia, 1985; 57: 214-219.
15. Innes IR, Nickerson M. Atropine, scopolamine, and related antimuscarinic drugs. In: The Pharmacological Basis of Therapeutics. (eds Goodman LS, Gilman A) 5th edn. MacMillan Publishing Co, Inc., New York, 1975: 514-532.
16. Hamlin RL, Smith CR. Effects of vagal stimulation on S-A and A-V nodes. American Journal of Physiology, 1968; 215: 560-568.
17. Smith DF. Presurgical care of the equine colic patient. Cornell Veterinarian, 1978; 68 (Suppl. 7): 113-121.
18. Littlejohn A. The surgical relief of intestinal obstruction in horses: a review. The effect of intestinal obstruction. British Veterinary Journal, 1965; 121: 568-576.
19. Alexander R. The effect of some anti-diarrhoeal drugs on intestinal transit and faecal excretion of water and electrolytes in the horse. Equine Veterinary Journal, 1978; 10: 229-234.
20. Lowe JE, Sellers AF, Brandum J. Equine pelvic flexure impaction of a model used to evaluate motor events and compare drug response. Cornell Veterinarian, 1980; 70: 401-412.
21. Davis LE, Knight AP. Review of the clinical pharmacology of the equine digestive system. Journal of Equine Medicine and Surgery, 1977; 1: 27-35.
22. Bueno L, Ruckebusch Y, Dorchies P. Disturbances of digestive motility in horses associated with strongyle infection. Veterinary Parasitology, 1979; 5: 253-260.
23. Hsu WH, Lee P, Betts DM. Xylazine-induced mydriasis in rats and its antagonism by adrenergic blocking agents. Journal of Veterinary Pharmacology and Therapeutics, 1981; 4: 97-101.
24. Hsu WH, Betts DM, Lee P. Xylazine-induced mydriasis. possible involvement of a central post synaptic regulation of parasympathetic tone. Journal of Veterinary Pharmacology and Therapeutics, 1981; 4: 209-214.