Effects of antimony compounds on foetal development in rats

Journal of Applied Animal Research

Volumn 10, Issue 1, 1996, Pages 15-24

  Alkhawajah, A M ^a   Jain, S ^a   Larbi, E B ^a,b  

^a Departments of Pharmacology   (Saudi Arabia)

^b IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Antimonials; Antimony toxicity; Leishmaniasis; Teratogenicity

Indexed keywords

EID: 0004758503     PISSN: 09712119     EISSN: 09741844     Source Type: Journal    
DOI: 10.1080/09712119.1996.9706126     Document Type: Article

References (16)

1. Alkhawajnh, A. M., Larbi, E. B., Jain, S., AI-Gindan, Y. and Abahussain, A. 1992. Subaoute toxicity of pentavalent antimony compounds in rats. Human and bixp. Toxiool., 11: 283-288.
2. Bnrrow, M.V. and Taylor, J.W. 1969. A rapid method for detecting malformations in rat foetuses. J. Morphol., 127: 291-306.
3. Bryceson, A.D.M. 1987. Therapy in man. In: The Leishmaniases in Biology and Medicine. W. Peters and R. Killick-Kendrick, Eds. Ac a demie Press, Iiondon, pp 848-907.
4. Bryceson, A.D.M., Chulay, J.D., Mugambi, M., Were, J.B., Gachichi, G., Chunge, C.N., Mivigai, R., Bhatt, S.M.H.M., Spencer, H.C., Même, J. and Anabwani, G. 1985. Viscéral Leishmaniasis unresponsive to antimonial drugs II: Response to high dose of sodium stibogluconate or prolonged treatraent with pentamidine. Transactions of the Royal Society of Tropical Medicine and Hygiene, 79 : 705-714.
5. Chulay, J.D., Spencer, H.C. and Mugambi, M. 1985. Electrocardiographic changes during treatraent of leishraaniasis with pentavalent antimony (sodium stibogluconate). Am. J. Trop. Med. Hyg., 34 : 702-709.
6. Ferrando, G. and Nalbandov, A.V. 1968. Relative improtance of histamine and oestrogen on implantation in rats. Endocrinology, 83 : 933.
7. Gellhom, A., Tupikova, N.A. and van Dyke, H.B. 1946. The tissues distribution and excretion of four organic antimonials after single or repeated administration to normal hamsters. J. Pharmacy, 27 : 169-180.
8. Giraud, P., Bernard, R., Orsini, A. and Coigner, J. 1961. Données nouvelles sur le trraitement du kala-azar (leishmaniose visceralemediterraneenne). Arch. Française de Pédiatrie, 18 : 1002-1013
9. Hepburn, N.C., Siddique, I., Howie, A.F., Beckett, G.J. and Hayes, P.C. 1994. Hepatotoxicity of sodium stibogluconate therapy for American leisharaaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 88 : 453-456.
10. Kahlson, G. 1960. A place for histamine in normal physiology. Lancet, 1: 67-70.
11. Larbi, E.B., Alkhawajah, A., Al-Gindan, Y., Jain, S., Abahusain, A. and Alzayer, A. 1995. A randomized, double blind, clinical trial of topical clotrimazole versus miconazole for treatraent of cutaneous leishmaniasis in the Eastern Province of Saudi Arabia. Am. J. Trop. Med. Hyg., 52 (2) : 166-168.
12. Marcus, G.J., Shelesnyak, M.C. and Kraicer, F. 1964. Studies on the mechanism of nidation : X. The oestrogen surge, histamine release and decidual induction in the rat. Acta Endocrinol. (Copenhagen), 47 : 255-258.
13. Rees, P.H., Kager, P.A., Keating, M.I. and Hockeyer, W.T. 1980. Rénal clearance of pentavalent antimony (sodium stibogluconate). Lancet, 2 : 226-229.
14. Runner, N.M. and Dagg, C.P. 1960. Metabolic mechanisms of tératogénie agents cluring morphogenesis. Symposium on normal and abnormal diflerentiation and development. U.S. National Cancer Institute Monograph No. 2, pp. 41-45.
15. Wasuniia, K.M., Haynes, J.G., Were, J.B.O., Muigai, R., Sherwood, J., Gachihi, G., Carpenter, L. and McAdam, K.P.W.J. 1995. Acute phase protein concentrations predict parasite clearance rate during therapy for viscéral leishmaniasis. Trans. Roy Soc. Trop. Med. Hyg., 89 : 678-682.
16. Wilson, J.G. 1973. Atlas of free hand (razor blade) sections of normal 20-day rat foetus. In : Environment and Birth Dcfccts. D.H.K. Lee, E.W. Hewson, I) Okun, Eds. Academic Press, New York, pp 227-233.