An antimalarially active cyclic peroxy ketal

Heterocycles

Volumn 47, Issue 2, 1998, Pages 643-646

  Posner, Gary H ^a   O'Dowd, Hardwin ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0004733836     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-97-s(n)61     Document Type: Article

References (14)

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2. J.N. Cumming, P. Ploypradith, and G.H. Posner, Adv. Pharmacol., 1997, 37, 253.
3. T.R. Sweeney, Med. Res. Rev., 1981, 1, 281.
4. R.S. Goldsmith in Basic and Clinical Pharmacology, 5th ed. B.G. Katzung, Ed., Appleton and Lange, Norwalk, CT, 1992, p. 735.
5. W.-S. Zhou and X.X. Xu, Acc. Chem. Res., 1994, 27, 211.
6. G.H. Posner, D. Wang, L. Gonzalez, X. Tao, J.N. Cumming, D. Klinedinst, and T.A. Shapiro, Tetrahedron Lett., 1996, 37, 7225.
7. B.B. Snider and Z. Shi, J. Am. Chem. Soc., 1992, 114, 1790.
8. See also B.B. Snider, Z. Shi, S.V. O'Neill, K.K. Kreuter, and T. Arakaki, J. Org. Chem., 1994, 59, 1726.
9. For synthesis of cyclic peroxy hemiketals see: a) C.-Y. Qian, T. Yamada, H. Nishino, and K. Kurosawa, Bull. Chem. Soc. Japan, 1992, 65, 1371
10. b) C.-Y. Qian, H. Nishino, K. Kurosawa, and J.D. Korp, J. Org. Chem., 1993, 58, 4448
11. P.H. Dussault and K.R. Woller, J. Am. Chem. Soc., 1997, 119, 3824.
12. For a naturally occurring cyclic peroxy hemiketal, see W.-Y. Tsui and G.D. Brown, Tetrahedron, 1996, 52, 9735.
13. Characterization of new compounds was achieved spectroscopically and by high resolution mass spectroscopy.
14. G.H. Posner, J.N. Cumming, P. Ploypradith, and C.H. Oh, J. Am. Chem. Soc., 1995, 117, 5885.