Detection and minimization of H-phosphonate side reaction during phosphopeptide synthesis by a post-assembly global phosphorylation strategy

Letters in Peptide Science

Volumn 3, Issue 6, 1997, Pages 333-342

  Xu, Qinghong ^a,b   Ottinger, Elizabeth A ^a,c   Solé, Nuria A ^a,d   Barany, George ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c JOSLIN DIABETES CENTER   (United States)

^d Qual Controlled Biochemicals Inc   (United States)

Author keywords

Gel phase nuclear magnetic resonance; H phosphonate byproduct; Phosphopeptides; Phosphoramidite chemistry; Post assembly phosphorylation; Solid phase peptide synthesis

Indexed keywords

EID: 0004690905     PISSN: 09295666     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf00127964     Document Type: Article

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