Rational enzyme design: Computer modeling and site-directed mutagenesis for the modification of catalytic specificity in organophosphorus hydrolase

Chimia

Volumn 50, Issue 9, 1996, Pages 430-431

  Lai, Kaihua ^a   Grimsley, Janet K ^a   Kuhlmann, Barbara D ^a   Scapozza, Leonardo ^b   Harvey, Steven P ^c   DeFrank, Joseph J ^c   Kolakowski, Jan E ^c   Wild, James R ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b ETH ZURICH   (Switzerland)

^c Devmt   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0004650979     PISSN: 00094293     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. B. Xu, J.R. Wild, C.M. Kenerley, J. Fermentation and Bioengineering 1996, 81, 473.
2. J.K. Grimsley, V.K. Ratogi, J.R. Wild, 'Biological Systems for the Detoxification of Organophosphorus Neurotoxins: Potential for Environmental Remediation Applications', in 'Bioremediation: Principles and Practice', Eds. S.K. Sikdar and R.L. Irvine, Technomic Publishing Co. Inc., 1996, in press.
3. E.I. Rainina, A.L. Simonian, E.N. Elremenco, S.D. Varfolomeyev, J.R. Wild, Biosensors and Bioelectronics 1996, in press.
4. K. Lai, N.J. Stolowich, Arch. Biochem. Biophys. 1995, 318, 59.
5. F. Yang, J.R. Wild, A.L. Russell, Biotechnol. Prog. 1995, 11, 71.
6. F.C.G. Hoskin, J.E. Walker, W-D. Dettbarn, J.R. Wild, Biochem. Pharmacol. 1995, 49, 711.
7. J.E. Kolakowski, J.J. DeFrank, K. Lai, J.R. Wild, 1996. submitted for publication.
8. K.I. Dave, L. Phillips, V.A. Luckow, J.R. Wild, Biotech. and Appl. Biochem. 1994, 19, 271.
9. K. Lai, K.I. Dave, J.R. Wild, J. Biol. Chem. 1994, 269, 16579.
10. L. Pei, G. Omburo, W.D. McGuinn, I. Petrikovics, K.I. Dave, F.M. Raushel, J.R. Wild, J.R. DeLoach, J.L. Way, Toxicol. Appl. Pharmacol. 1994, 124, 296.
11. K.I. Dave, C.E. Miller, J.R. Wild, Chem.-Biol. Interact. 1993, 87, 55.