Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 83, Issue 16, 1986, Pages 5978-5982

  Rice, G C ^a   Hoy, C ^a   Schimke, R T ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; METHOTREXATE;

ANIMAL CELL; CELL CULTURE; CHEMOTHERAPY; CHO CELL; CYTOLOGY; DRUG RESISTANCE; ETIOLOGY; FEMALE GENITAL SYSTEM; GENE AMPLIFICATION; GENETIC ENGINEERING; HEREDITY; HYPOXIA; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; THERAPY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0004580887     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.83.16.5978     Document Type: Article

References (0)