Micronucleus monitoring to assess human occupational exposure to organochlorides

Environmental and Molecular Mutagenesis

Volumn 29, Issue 1, 1997, Pages 46-52

  Augusto, Lia Giraldo Da Silva ^a   Lieber, Sofia Rocha ^b   Ruiz, Milton Artur ^c   De Souza, Cármino Antonio ^b  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c Department of Cardiovascular Surgery   (Brazil)

Author keywords

Clastogenesis; Hexachlorobenzene; Human monitoring; Micronuclei; Organochlorinides

Indexed keywords

CARBON TETRACHLORIDE; HEXACHLOROBENZENE; ORGANOCHLORINE DERIVATIVE; TETRACHLOROETHYLENE;

ARTICLE; BIOLOGICAL MONITORING; BRAZIL; CARCINOGENESIS; CHEMICAL INDUSTRY; CONTROLLED STUDY; GENOTOXICITY; HUMAN; HUMAN CELL; MALE; METHODOLOGY; MICRONUCLEUS TEST; OCCUPATIONAL EXPOSURE; PERIPHERAL LYMPHOCYTE;

ADULT; BRAZIL; CHEMICAL INDUSTRY; CHLORIDES; HEXACHLOROBENZENE; HUMANS; HYDROCARBONS, CHLORINATED; MICRONUCLEUS TESTS; MIDDLE AGED; OCCUPATIONAL EXPOSURE; TIME FACTORS;

EID: 0004525310     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1997)29:1<46::AID-EM6>3.0.CO;2-B     Document Type: Article

References (19)

1. Bolognesi C, Parrini M, Bonassi S, Ianello G, Salanitto A (1993): Cytogenetic analysis of human population occupationally exposed to pesticides. Mutat Res 285:239-249.
2. Cabral JRP, Shubik P, Mollner T, Raitano F (1977): Carcinogenic activity of hexachlorobenzene in hamster. Nature 269:510-511.
3. Cabral JRP, Mollner T, Raitano F, Shubik P (1979): Carcinogenesis of hexachlorobenzene in mice. Int J Cancer 23:47-51.
4. Cid GM, Loria D, Vilenky M, Miotti JL, Matos E (1991): Leather tanning workers: Chromosomal aberrations in peripheral lymphocytes and micronuclei in exfoliated cells in urine. Mutat Res 259:197-207.
5. Dale WE, Curley A, Curto C (1966): Hexane extractable chlorinated insecticides in human blood. Life Sci 5:47.
6. Fenech M, Morley AA (1984): Measurement of micronuclei in lymphocytes. Mutat Res 147:29-36.
7. a J Nacl Hexaclorobenzeno 239.
8. Högstedt B (1984): Micronuclei in lymphocytes with preserved cytoplasm. A method for assessment of cytogenetic damage in man. Mutat Res 130:63-72.
9. Högstedt B, Hedner K, Mark-Vendel E, Mitelman F, Schültz A, Skervin S (1979): Increased frequency of chromosome aberrations in workers exposed to styrene. Scand J Work Environ Health 5:333-533.
10. International Agency for Research on Cancer (1979): "Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans." Lyon: IARC, vol 20, pp 155-178.
11. Mäki-Paakkanen J (1987): Chromosome aberrations, micronuclei and sister-chromatid exchanges in blood lymphocytes after occupational exposure to low levels of styrene. Mutat Res 189:399-406.
12. Mäki-Paakkanen J, Walles S, Osterman-Golkar S, Norppa H (1991): Single-strand breaks, chromosome aberrations, sister-chromatid exchanges and micronuclei in blood lymphocytes of workers exposed to styrene during the production of reinforced plastics. Environ Mol Mutagen 17:27-31.
13. Meng Z, Zhang L (1990): Observation of frequencies of lymphocytes with micronuclei in human peripheral blood cultures from workers in a sulphuric acid factory. Environ Mol Mutagen 15:218-120.
14. Migliore L, Parrini M, Sbrana I, Biagini C, Battaglia A, Loprieno N (1991): Micronucleated lymphocytes in people occupationally exposed to potential environmental contaminants: The age effect. Mutat Res 256:13-20.
15. a J Nacl Hexaclorobenzeno 23-24.
16. Nordenson I, Beckman L (1984): Chromosomal aberrations in lymphocytes of workers exposed to low levels of styrene. Hum Hered 34:178-182.
17. Schmid W (1973): Chemical mutagen testing in vivo somatic mammalian cell. Agents Action 3:77-85.
18. Sorsa M, Pyy L, Salomaa S, Nylund L, Yager JW (1988): Biological and environmental monitoring of occupational exposure to cyclophosphamide in industry and hospitals. Mutat Res 204:465-479.
19. Zhang L, Moire LR, Kolachana P, Davison A, Smith MT (1993): Benzene metabolite 1,2,4-benzenetriol induces micronuclei and oxidative DNA damage in human lymphocytes and HL60 cells. Environ Mol Mutagen 21:339-348.