Immortalization of human uroepithelial cells by human papillomavirus 16 E6 or E7

Radiation Oncology Investigations

Volumn 3, Issue 6, 1995, Pages 368-376

  Belair, Cassandra D ^b,c   Blelloch, Robert H ^a   Reznikoff, Catherine A ^a,b,c  

^a Department of Human Oncology ^*  (United States)

^b Environmental Toxicology Center   (United States)

^c UNIVERSITY OF WISCONSIN   (United States)

Author keywords

HPV E6 or E7; human uroepithelial cells; immortalization

Indexed keywords

EID: 0004426654     PISSN: 10657541     EISSN: 15206823     Source Type: Journal    
DOI: 10.1002/roi.2970030623     Document Type: Article

References (34)

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2. Characterization of human uroepithelial cells immortalized in vitro by simian virus 40
3. Losses of 3p, 11p, and 13p in EJ/ras‐transformable simian virus 40‐immortalized human uroepithelial cells
4. Tumorigenic transformation and neoplastic progression of human uroepithelial cells after exposure in vitro to 4‐Aminobiphenyl or its metabolites
5. Neoplastic progression by EJ/ras at different steps of transformation in vitro of human uroepithelial cells
6. Allelic 3p deletions in high‐grade carcinomas after transformation in vitro of human uroepithelial cells
7. Nonrandom chromosome losses in stepwise neoplastic transformation in vitro of human uroepithelial cells
8. Chromosome losses in tumorigenic revertants of EJ/ras‐expressing somatic cell hybrids
9. Nonrandom chromosome losses in tumorigenic revertants of hybrids between isogeneic immortal and neoplastic human uroepithelial cells
10. Role of SV40 T antigen binding to pRB and p53 in multistep transformation in vitro of human uroepithelial cells
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14. High‐risk human papillomavirus infections and overexpression of p53 protein as prognostic indicators in transitional cell carcinoma of the urinary bladder
15. Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products
16. Long‐term genome stability and minimal genotypic and phenotypic alterations in HPV 16 E7‐, but not E6‐, immortalized human uroepithelial cells
17. The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells
18. E6 of human papillomavirus type 16 can overcome the Ml stage of immortalization in human mammary epithelial cells but not in human fibroblasts
19. Elevated wildtype p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus 16 E7 gene
20. Immortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7
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24. Evolution of in vitro transformation and tumorigenesis of HPV 16 and HPV 18 immortalized primary cervical epithelial cells
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26. Progression of human papillomavirus type 18‐immortalized human keratinocytes to a malignant phenotype
27. Induction of chromosome abnormalities in mouse and human epidermal keratinocytes by the human papillomavirus type 16 E7 oncogene
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29. Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV‐E6E7 ORFS)
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32. p53 Mutations in human cancers
33. The retinoblastoma protein and cell cycle control