Single Step Conversion of Chiral Carnitine and Derivatives into (S)- and (R)-β-Substituted-γ-Butyrolactones

Synlett

Volumn 1997, Issue 1, 1997, Pages 71-74

  Calvisi, Giuseppina ^c   Catini, Roberto ^c   Chiariotti, Wilma ^c   Giannessi, Fabio ^a   Muck, Sandra ^c   Tinti, Maria Ornella ^c   De Angelis, Francesco ^b  

^a Sigma Tau SpA   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0003900798     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1997-686     Document Type: Article

References (35)

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24. 3: C, 47.06; H, 5.92. Found C, 46.88; H, 5.83.
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26. 6 is a known compound used as intermediate in several syntheses: a) McGarvey, G. J.; Williams, J. M., Hiner, R. N.; Matsubara, Y.; Oh, T. J. Am. Chem. Soc. 1986, 108, 4943-4952;
27. b) Rinehart, K. L.; Harada, K.; Namikoshi, M.; Chen, C.; Harvis, C. A. J. Am. Chem. Soc. 1988, 110, 8557-8558;
28. 2O, (R) form).
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30. 4 0.02 M, flow rate = 0.5 mL/min, temperature = 0°C, retention time = 3.15 min.
31. 2: C, 57.15; H, 4.79; Found C, 57.06; H, 4.64.
32. 3: C, 55.53; H, 7.65; N, 9.29; Cl, 11.71. Found C, 55.31; H, 7.93; N, 9.20; Cl, 11.53.
33. 3: C, 63.75; H, 6.32; N, 6.75. Found C, 63.75; H, 6.60; N, 6.71.
34. 3: C, 63.75; H, 6.32; 6.75. Found: C, 63.63; H, 6.61; N, 6.78.
35. Kilenyi, S. N. in Comprehensive Organic Synthesis, Vol. 7; Trost, B. M.; Fleming, I., Eds; Ley, S. V., Vol. Ed.; Pergamon Press: Oxford, 1991, p. 653.