Enantiomerically pure cyclopropyl hemiacetals: Lipase-catalyzed synthesis of chiral, nonracemic ester homoenolate equivalents

Organic Letters

Volumn 3, Issue 2, 2001, Pages 189-191

  Westermann, Bernhard ^a   Krebs, Birte ^a  

^a UNIVERSITY OF PADERBORN   (Germany)

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EID: 0003547662     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol006752f     Document Type: Article

References (25)

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21. We used a 6-TBDMS-3-butyrate-2-methyl-β-cyclodextrin-modified GLC column.
22. CALB has been provided by Novo Nordisk; PCL has been purchased from Sigma. The bacterial species PC has been renamed recently (Burkholderia cepacia), but we contiunue to use the traditional name.
23. We screened 11 different upases and 3 different estereases (from Altus, Amano, Novo, and Fluka).
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