Rapid induction of 7H6 tight junction-associated protein and paracellular barrier function in capillary endothelial cells of porcine brain in vitro by treatment with astrocyte conditioned medium and cAMP

Medical Molecular Morphology

Volumn 30, Issue 1, 1997, Pages 8-14

  Yamada Sasamori, Yumiko ^a   Baba, Takeo ^a   Sawada, Norimasa ^a   Tobioka, Hirotoshi ^a   Isomura, Hiroshi ^a   Hashi, Kazuo ^a   Mori, Michio ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

7H6 antigen; Astrocyte; Blood brain barrier; Brain capillary endothelium; Permeability; Tight junction

Indexed keywords

EID: 0003052998     PISSN: 18601480     EISSN: 18601499     Source Type: Journal    
DOI: 10.1007/BF01458346     Document Type: Article

References (31)

1. Stevenson BR, Siliciano JD, Mooseker MS, Goodenough DA (1986) Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol 103:755-766
2. Citi S, Sabanay H, Jakes R, Geiger B, Kendrick-Jones J (1988) Cingulin, a new peripheral component of tight junctions. Nature 333:272-276
3. Gumbiner B, Lowenkopf T, Apatira D (1991) Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci USA 88:3460-3464
4. Balda MS, Gonzalez-Mariscal L, Matter K, Cereijido M, Anderson JM (1993) Assembly of the tight junction: the role of diacylglycerol. J Cell Biol 123:293-302
5. Furuse M, Hirase T, Itoh M, Nagafuchi A, Yonemura S, Tsukita S, Tsukita S (1993) Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol 123:1777-1788
6. Zahraoui A, Joberty G, Arpin M, Fontaine JJ, Hellio R, Tavitian A, Louvard D (1994) A small rab GTPase is distributed in cytoplasmic vesicles in nonpolarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells. J Cell Biol 124:101-115
7. Rubin LL (1992) Endothelial cells: adhesion and tight junctions. Curr Opin Cell Biol 4:830-833
8. Zhong Y, Saitoh T, Minase T, Sawada N, Enomoto K, Mori M (1993) Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J Cell Biol 120:477-483
9. Zhong Y, Enomoto K, Isomura H, Sawada N, Minase T, Oyamada M, Konishi Y, Mori M (1994) Localization of the 7H6 antigen at tight junctions correlates with the paracellular barrier function of MDCK cells. Exp Cell Res 214:614-620
10. Satoh H, Zhong Y, Isomura H, Saitoh M, Enomoto K, Sawada N, Mori M (1996) Localization of 7H6 tight junction-associated antigen along the cell border of vascular endothelial cells correlates with paracellular barrier function against ions, large molecules and cancer cells. Exp Cell Res 222:269-274
11. Tobioka H, Sawada N, Zhang Y, Mori M (1996) Enhanced paracellular barrier function of rat mesothelial cells partially protects against cancer cell penetration. Br J Cancer 74:439-445
12. Rubin LL, Hall DE, Porter S, Barbu K, Cannon C, Horner HC, Janatpour M, Liaw CW, Manning K, Morales J, Tanner LI, Tomaselli KJ, Bard F (1991) A cell culture model of the blood-brain barrier. J Cell Biol 115:1725-1735
13. Abbott NJ, Hughes CCW, Revest PA, Greenwood J (1992) Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier. J Cell Sci 103:23-37
14. Noble M, Fok-Seang J, Cohen J (1984) Glia are a unique substrate for the in vitro growth of central nervous system neurons. J Neurosci 4:1892-1903
15. Ma TY, Hollander D, Bhalla D, Nguyen H, Krugliak P (1992) IEC-18, a nontransformed small intestinal cell line for studying epithelial permeability. J Lab Clin Med 120:329-341
16. Folkman J, Haudenschild CC, Zetter BR (1979) Long-term culture of capillary endothelial cells. Proc Natl Acad Sci USA 76:5217-5221
17. Konari K, Sawada N, Zhong Y, Isomura H, Nakagawa T, Mori M (1995) Development of the blood-retinal barrier in vitro: formation of tight junctions as revealed by occludin and ZO-1 correlates with the barrier function of chick retinal pigment epithelial cells. Exp Eye Res 61:99-108
18. Zhong Y, Enomoto K, Tobioka H, Konishi Y, Satoh M, Mori M (1994) Sequential decrease in tight junctions as revealed by 7H6 tight junction-associated protein during rat hepatocarcinogenesis. Jpn J Cancer Res 85:351-356
19. Krause D, Mischeck U, Galla HJ, Dermietzel R (1991) Correlation of zonula occludens ZO-1 antigen expression and transendothelial resistance in porcine and rat cultured cerebral endotherlial cells. Neurosci Lett 128:301-304
20. Janzer RC, Raff MC (1987) Astrocytes induce blood-brain barrier properties in endothelial cells. Nature 325:253-257
21. Joo F (1992) The cerebral microvessels in culture, an update. J Neurochem 58:1-17
22. DeBault LE, Cancilla PA (1979) γ-Glutamyl transpeptidase in isolated brain endothelial cells: induction by glial cells in vitro. Science 207:653-655
23. Maxwell K, Berliner JA, Cancilla PA (1987) Induction of γ-glutamyl transpeptidase in cultured cerebral endothelial cells by a product released by astrocytes. Brain Res 410:309-314
24. Tontsch U, Bauer HC (1991) Glial cells and neurons induce blood-brain barrier related enzymes in cultured cerebral endothelial cells. Brain Res 539:247-253
25. Dehouck B, Dehouck MP, Fruchart JC, Cecchelli R (1994) Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes. J Cell Biol 126:465-473
26. Holash JA, Stewart PA (1993) The relationship of astrocyte-like cells to the vessels that contribute to the blood ocular barriers. Brain Res 629:218-224
27. Tao-Cheng JH, Nagy Z, Brightman MW (1987) Tight junctions of brain endothelium in vitro are enhanced by astroglia. J Neurosic 7:3293-3299
28. Dehouck MP, Méresse S, Delorme P, Fruchart JC, Cecchelli R (1990) An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro. J Neurochem 54:1798-1801
29. Wolburg H, Neuhaus J, Kniesel U, Krau ßB, Schmid EM, Öcalan M, Farrell C, Risau W (1994) Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes. J Cell Sci 107:1347-1357
30. Duffey ME, Hainau B, Ho S, Bentzel CJ (1981) Regulation of epithelial tight junction permeability by cyclic AMP. Nature 294:451-453
31. Stelzner TJ, Weil JV, O'Brien RF (1989) Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties. J Cell Physiol 139:157-166