Indium trifluoride - A Lewis acid catalyst for the addition of TMSCN to aldehydes in water

Synlett

Volumn , Issue 4, 1998, Pages 369-370

  Loh, Teck Peng ^a   Xu, Kai Chen ^a   Ho, Diana Sook Chiang ^a   Sim, Keng Yeow ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002961546     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1676     Document Type: Article

References (25)

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25. 3 (0.3 eq) in water (3 mL) was added TMSCN (2 eq.). The reaction mixture was stirred vigorously overnight at room temperature. After usual extraction workup, the respective cyanohydrins were isolated. From our experience, vigorous stirring is very important for these organic reactions in water.