Dose response of sheep poisoned with locoweed (Oxytropis sericea)

Journal of Veterinary Diagnostic Investigation

Volumn 11, Issue 5, 1999, Pages 448-456

  Stegelmeier, Bryan L ^a   James, Lynn F ^a   Panter, Kip E ^a   Gardner, Dale R ^a   Pfister, James A ^a   Ralphs, Michael H ^a   Molyneux, Russell J ^b  

^a USDA ARS POISONOUS PLANT RESEARCH LABORATORY   (United States)

^b WESTERN REGIONAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; BRAIN; DOSE RESPONSE; DRUG EFFECT; INTOXICATION; MALE; OXYTROPIS; PATHOLOGY; SHEEP; SHEEP DISEASE; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; OXYTROPIS; POISONING; SHEEP; SHEEP DISEASES; TISSUE DISTRIBUTION;

EID: 0002961477     PISSN: 10406387     EISSN: None     Source Type: Journal    
DOI: 10.1177/104063879901100510     Document Type: Article

References (37)

1. Alroy J, Orgad U, Ucci AA, Gavris VE: 1985, Swainsonine toxicosis mimics lectin histochemistry of mannosidosis. Vet Pathol 22:311-316.
2. Bagriacik EU, Kirkpatrick A, Miller KS: 1996, Glycosylation of native mhc class ia molecules is required for recognition by allogeneic cytotoxic T lymphocytes. Glycobiology 6:413-421.
3. Bowen D, Adir J, White SL, et al.: 1993, A preliminary pharmacokinetic evaluation of the antimetastatic immunomodulator swainsonine: clinical and toxic implications. Anticancer Res 13: 841-844.
4. Bowlin TL, McKown BJ, Kang MS, Sunkara PS: 1989, Potentiation of human lymphokine-activated killer cell activity by swainsonine, an inhibitor of glycoprotein processing. Cancer Res 49:4109-4113.
5. Bowlin TL, Schroeder KK, Fanger BO: 1991, Swainsonine, an inhibitor of mannosidase II during glycoprotein processing, enhances concanavalin A-induced T cell proliferation and interleukin 2 receptor expression exclusively via the T cell receptor complex. Cell Immunol 137:111-117.
6. Bowlin TL, Sunkara PS: 1988, Swainsonine, an inhibitor of glycoprotein processing, enhances mitogen-induced interleukin 2 production and receptor expression in human lymphocytes. Biochem Biophys Res Commun 151:859-864.
7. Carson FL: 1997, Histotechnology: a self instructional text. ASCP Press, Hong Kong.
8. Chui D, Oheda M, Liao YF, et al.: 1997, Alpha mannosidase II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis. Cell 90:157-167.
9. Das PC, Roberts JD, White SL, Olden K: 1995, Activation of resident tissue specific macrophages by swainsonine. Oncol Res 7:425-433.
10. Elbein AD, Solf R, Dorling PR, Vosbeck K: 1981, Swainsonine: an inhibitor of glycoprotein processing. Proc Natl Acad Sci USA 78:7393-7397.
11. Hattori M, Ozawa K, Wakabayashi K: 1988, Biosynthesis and secretion of lutropin in rat gonadotropes treated with swainsonine. Acta Endocrinol Copenh 119:132-138.
12. James LF, Hartley WF, Van Kampen KR, Nielsen D: 1983, Relationship between ingestion of the locoweed Oxytropis sericea and congestive right-sided heart failure in cattle. Am J Vet Res 44:254-259.
13. James LF, Van Kampen KR, Johnson AE: 1970, Physiopathologic changes in locoweed poisoning of livestock. Am J Vet Res 31:663-672.
14. Karasuno T, Kanayama Y, Nishiura T, et al: 1992, Glycosidase inhibitors (castanospermine and swainsonine) and neuraminidase inhibit pokeweed mitogen-induced B cell maturation. Eur J Immunol 22:2003-2008.
15. McNally AK, Defife KM, Anderson JM: 1996, Interleukin 4 induced macrophage fusion is prevented by inhibitors of mannose receptor activity. Am J Pathol 149:975-985.
16. Molyneux RJ, James LF: 1982, Loco intoxication: indolizidine alkaloids of spotted locoweed (Astragalus lentiginosus). Science 216:190-191.
17. Molyneux RJ, James LF, Panter KE, Ralphs MH: 1989, The occurrence and detection of swainsonine in locoweeds. In: Swainsonine and related glycosidase inhibitors, ed. James LF, Elbein A, Molyneux RJ, Warren CD, pp. 100-117. Iowa State University Press, Ames, IA.
18. Pan YT, Ghidoni J, Elbein AD: 1993, The effects of castanospermine and swainsonine on the activity and synthesis of intestinal sucrase. Arch Biochem Biophys 303:134-144.
19. Pritchard DH, Huxtable CRR, Dorling PR: 1990, Swainsonine toxicosis suppresses appetite and retards growth in weanling rats. Res Vet Sci 48:228-230.
20. Ralphs MH, James LF: 1999, Locoweed poisoning. J Nat Toxins 8:47-51.
21. Ralphs MH, Graham D, Molyneux RJ, James LF: 1993, Seasonal grazing of locoweeds by cattle in northeastern New Mexico. J Range Manage 46:416-420.
22. Ralphs MH, James JF, Panter KE, Stegelmeier BL, Pfister JA, Molyneux RJ: 1996, Locoweed research to reduce livestock poisoning on western US rangelands. In Rangelands in a Sustainable Biosphere, West NE ed. Society for Range Management, Denver, CO, pp 462-463.
23. Ralphs MH, Mickelsen LV, Turner DL: 1987, Cattle grazing white locoweed: diet selection patterns of native and introduced cattle. J Range Manage 40:333-335.
24. Ralphs MH, Panter KE, James LF: 1990, Feed preferences and habituation of sheep poisoned by locoweed. J Anim Sci 68: 1354-1362.
25. Ralphs MH, Pfister JA: 1992, Cattle diets in tall forb communities on mountain rangelands. J Range Manage 45:534-537.
26. Sarkar K, Sarkar HS, Kole L, Das PK: 1996, Receptor mediated endocytosis of fucosylated neoglycoprotein by macrophages. Mol Cell Biochem 156:109-116.
27. Stegelmeier BL, James LF, Panter KE, et al.: 1998, Tissue swainsonine clearance in sheep chronically poisoned with locoweed (Oxytropis sericea). J Anim Sci 76:1140-1144.
28. Stegelmeier BL, James LF, Panter KE, Molyneux RJ: 1995, Serum swainsonine concentration and alpha-mannosidase activity in cattle and sheep ingesting Oxytropis sericea and Astragalus lentiginosus (locoweeds). Am J Vet Res 56:149-154.
29. Stegelmeier BL, James LF, Panter KE, Molyneux RJ: 1995, Tissue and serum swainsonine concentrations in sheep ingesting Astragalus lentiginosus (locoweed). Vet Hum Toxicol 37:336-339.
30. Stegelmeier BL, Molyneux RJ, Elbein AD, James LF: 1995, The lesions of locoweed (Astragalus mollissimus), swainsonine, and castanospermine in rats. Vet Pathol 32:289-298.
31. Stegelmeier BL, Snyder PD, James LF, et al.: The immunologic and toxic effects of chronic locoweed (Astragalus lentiginosus) intoxication in cattle. In: Toxic plants and other natural toxicants, ed. Garland T, Barr AC, pp. 285-290. CAB International, Wallingford, Oxon, UK.
32. Tulsiani DRP, Broquist HP, Touster O: 1985, Marked differences in the swainsonine inhibition of rat liver lysosomal alpha-D-mannosidase, rat liver Golgi mannosidase II, and jack bean alpha-D-mannosidase. Arch Biochem Biophys 236:427-434.
33. Tulsiani DR, Touster O: 1992, Evidence that swainsonine pretreatment of rats leads to the formation of autophagic vacuoles and endosomes with decreased capacity to mature to, or fuse with, active lysosomes. Arch Biochem Biophys 296:556-561.
34. Van-Kampen KR, James LF: 1969, Pathology of locoweed poisoning in sheep. Pathol Vet 6:413-423.
35. Van-Kampen KR, James LF: 1970, Pathology of locoweed (Astragalus lentiginosus) poisoning in sheep. Sequential development of cytoplasmic vacuolation in tissues. Pathol Vet 7:503-508.
36. Van Kampen KR, James LF: 1972, Sequential development of the lesions in locoweed poisoning. Clin Toxicol 5:575-580.
37. White SL, Schweitzer K, Humphries MJ, Olden K: 1988, Stimulation of DNA synthesis in murine lymphocytes by the drug swainsonine: immunomodulatory properties. Biochem Biophys Res Commun 150:615-625.