The Role of Activity in Synaptic Competition at the Neuromuscular Junction

NIPS 1995: Proceedings of the 8th International Conference on Neural Information Processing Systems

Volumn , Issue , 1995, Pages 96-102

  Joseph, Samauel R H ^a   Willshaw, David J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY-DEPENDENT; COMPUTATIONAL MODELLING; CONSTRAINTS MODELS; DUAL CONSTRAINTS; ENDPLATES; EXTENDED VERSIONS; MOLECULAR LEVELS; NEUROMUSCULAR JUNCTIONS;

EID: 0002908363     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (17)

1. Andreose J. S., Fumagalli G. & Lømo T. (1995) Number of junctional acetylcholine receptors: control by neural and muscular influences in the rat. Journal of Physiology 483.2:397-406.
2. Axelrod D., Ravdin P., Koppel D. E., Schlessinger J., Webb W. W., Elson E. L. & Podleski T. R. (1976) Lateral motion of fluorescently labelled acetylcholine receptors in membranes of developing muscle fibers. Proc. Natl. Acad. Sci. USA 73:4594-4598.
3. Balice-Gordon R. J. & Lichtman J. W. (1994) Long-term synapse loss induced by focal blockade of postsynaptic receptors. Nature 372:519-524.
4. Bennett M. R. & Robinson J. (1989) Growth and elimination of nerve terminals during polyneuronal innervation of muscle cells: a trophic hypothesis. Proc. Royal Soc. Lond. [Biol] 235:299-320.
5. Bliss T. V. P. & Collingridge G. L. (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-39.
6. Colman H. & Lichtman J. W. (1992) 'Cartellian' competition at the neuromuscular junction. Trends in Neuroscience 15, 6:197-199.
7. Fladby T. & Jansen J. K. S. (1987) Postnatal loss of synaptic terminals in the partially denervated mouse soleus muscle. Acta. Physiol. Scand 129:239-246.
8. Gouze J. L., Lasry J. M. & Changeux J.-P. (1983) Selective stabilization of muscle innervation during development: A mathematical model. Biol Cybern. 46:207-215.
9. Jennings C. (1994) Death of a synapse. Nature 372:498-499.
10. Lo Y. J. & Poo M. M. (1991) Activity-dependent synapse competition in vitro: heterosynaptic suppression of developing synapses. Science 254:1019-1022.
11. McMahan U. J. (1990) The Agrin Hypothesis. Cold Spring Harbour Symp. Quant. Biol. 55:407-419.
12. Nitida R. M., Smith M. A., Magill C, Fallon J. R., Yao Y.-M. M., Wallace B. G. & McMahan U. J. (1987) Identification of agrin, a synaptic organising protein from Torpedo electric organ. Journal Cell Biology 105:2471-2478.
13. Rasmussen C. E. & Willshaw D. J. (1993) Presynaptic and postsynatic competition in models for the development of neuromuscular connections. B. Cyb. 68:409-419.
14. Ribchester R. R. (1993) Co-existence and elimination of convergent motor nerve terminals in reinnervated and paralysed adult rat skeletal muscle. J. Phys. 466: 421-441.
15. Ribchester R. R. & Barry J. A. (1994) Spatial Versus Consumptive Competition at Polyneuronally Innervated Neuromuscular Junctions. Exp. Physiology 79:465-494.
16. ++and phorbol ester. Journal of Cell Biol. 107:267-278.
17. Willshaw D. J. (1981) The establishment and the subsequent elimination of polyneuronal innervation of developing muscle: theoretical considerations. Proc. Royal Soc. Lond. B212: 233-252.