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Volumn 2, Issue 2, 1996, Pages 66-72

The human trisomy 21 brain: Insights from mouse models of Down syndrome

Author keywords

Alzheimer's disease; Down syndrome; Trisomy 16; Trisomy 21

Indexed keywords


EID: 0002906659     PISSN: 10804013     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1098-2779(1996)2:2<66::aid-mrdd2>3.3.co;2-g     Document Type: Article
Times cited : (6)

References (28)
  • 1
    • 0024498840 scopus 로고
    • Neurophysiological abnormalities in cultured dorsal root ganglion neurons from the trisomy 16 mouse fetus, a model for Down syndrome
    • Ault B, Caviedes P, Rapoport SI (1989): Neurophysiological abnormalities in cultured dorsal root ganglion neurons from the trisomy 16 mouse fetus, a model for Down syndrome. Brain Res 485:165-170.
    • (1989) Brain Res , vol.485 , pp. 165-170
    • Ault, B.1    Caviedes, P.2    Rapoport, S.I.3
  • 3
    • 0021827834 scopus 로고
    • Abnormalities of the nucleus basalis in Down's syndrome
    • Casanova MF, Walker LC, Whitehouse PJ et al. (1985): Abnormalities of the nucleus basalis in Down's syndrome. Ann Neurol 18:310-313.
    • (1985) Ann Neurol , vol.18 , pp. 310-313
    • Casanova, M.F.1    Walker, L.C.2    Whitehouse, P.J.3
  • 4
    • 0025293991 scopus 로고
    • Enhanced production of superoxide anion by microglia from trisomy 16 mice
    • Colton CA, Yao J, Gilbert D et al. (1990): Enhanced production of superoxide anion by microglia from trisomy 16 mice. Brain Res 519:236-242.
    • (1990) Brain Res , vol.519 , pp. 236-242
    • Colton, C.A.1    Yao, J.2    Gilbert, D.3
  • 5
    • 0025972390 scopus 로고
    • Nerve growth factor corrects developmental impairments of basal forebrain cholinergic neurons in the trisomy 16 mouse
    • Corsi P, Coyle JT (1991): Nerve growth factor corrects developmental impairments of basal forebrain cholinergic neurons in the trisomy 16 mouse. Proc Natl Acad Sci USA 88:1793-1797.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1793-1797
    • Corsi, P.1    Coyle, J.T.2
  • 6
    • 0018848828 scopus 로고
    • Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16
    • Cox DR, Epstein LB, Epstein CJ (1980): Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16. Proc Natl Acad Sci USA 77:2168-2172.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 2168-2172
    • Cox, D.R.1    Epstein, L.B.2    Epstein, C.J.3
  • 7
    • 0021378952 scopus 로고
    • Mouse trisomy 16 as an animal model of human trisomy 21 (Down syndrome): Production of viable trisomy 16 ↔ diploid mouse chimeras
    • Cox DR, Smith SA, Epstein LB et al. (1984): Mouse trisomy 16 as an animal model of human trisomy 21 (Down syndrome): Production of viable trisomy 16 ↔ diploid mouse chimeras. Dev Biol 101:416-424.
    • (1984) Dev Biol , vol.101 , pp. 416-424
    • Cox, D.R.1    Smith, S.A.2    Epstein, L.B.3
  • 8
    • 0023706984 scopus 로고
    • Down syndrome, Alzheimer's disease, and the trisomy 16 mouse
    • Coyle JT, Oster-Granite ML, Reeves RH et al. (1988): Down syndrome, Alzheimer's disease, and the trisomy 16 mouse. Trends Neurosci 11:390-394.
    • (1988) Trends Neurosci , vol.11 , pp. 390-394
    • Coyle, J.T.1    Oster-Granite, M.L.2    Reeves, R.H.3
  • 11
    • 0026078273 scopus 로고
    • Accleration of scrapie in trisomy 16 ↔ diploid aggregation chimeras
    • Epstein CJ, Foster DB, DeArmond SJ et al. (1991): Accleration of scrapie in trisomy 16 ↔ diploid aggregation chimeras. Ann Neurol 29:95-97.
    • (1991) Ann Neurol , vol.29 , pp. 95-97
    • Epstein, C.J.1    Foster, D.B.2    DeArmond, S.J.3
  • 12
    • 0028825042 scopus 로고
    • A behavioral assessment of Ts65DN mice, a putative Down syndrome model
    • Escorihuela RM, Fernandez-Teruel A, Vallina IF et al. (1995): A behavioral assessment of Ts65DN mice, a putative Down syndrome model. Neurosci Lett 199:143-146.
    • (1995) Neurosci Lett , vol.199 , pp. 143-146
    • Escorihuela, R.M.1    Fernandez-Teruel, A.2    Vallina, I.F.3
  • 13
    • 0025976448 scopus 로고
    • Mouse trisomy 16 neurons, a model of human trisomy 21 (Down syndrome), can be maintained by intracerebral transplantation
    • Fine A, Ault B, Rapoport SI (1991): Mouse trisomy 16 neurons, a model of human trisomy 21 (Down syndrome), can be maintained by intracerebral transplantation. Neurosci Lett 122:4.
    • (1991) Neurosci Lett , vol.122 , pp. 4
    • Fine, A.1    Ault, B.2    Rapoport, S.I.3
  • 14
    • 0027340019 scopus 로고
    • Cultured hippocampal neurons from trisomy 16 mouse, a model for Down's syndrome, have an abnormal action potential due to a reduced inward sodium current
    • Galdzicki Z, Coan E, Rapoport SI (1993): Cultured hippocampal neurons from trisomy 16 mouse, a model for Down's syndrome, have an abnormal action potential due to a reduced inward sodium current. Brain Res 604:69-78.
    • (1993) Brain Res , vol.604 , pp. 69-78
    • Galdzicki, Z.1    Coan, E.2    Rapoport, S.I.3
  • 15
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
    • Games D, Adams D, Alessandrini R et al. (1995): Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature 373:523-527.
    • (1995) Nature , vol.373 , pp. 523-527
    • Games, D.1    Adams, D.2    Alessandrini, R.3
  • 16
    • 0022871707 scopus 로고
    • Autosomal aneuploidy in mice: Generation and developmental consequences
    • Gearhart JD, Davisson MT, Oster-Granite ML (1986): Autosomal aneuploidy in mice: Generation and developmental consequences. Brain Res Bull 16:789-801.
    • (1986) Brain Res Bull , vol.16 , pp. 789-801
    • Gearhart, J.D.1    Davisson, M.T.2    Oster-Granite, M.L.3
  • 17
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
    • Goate A, Chartier-Harlon MC, Mullan M et al. (1991): Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349:704-706.
    • (1991) Nature , vol.349 , pp. 704-706
    • Goate, A.1    Chartier-Harlon, M.C.2    Mullan, M.3
  • 18
    • 0028070918 scopus 로고
    • Development of the superior temporal neocortex is anomalous in trisomy 21
    • Golden JA, Hyman BT (1994): Development of the superior temporal neocortex is anomalous in trisomy 21. J Neuropathol Exp Neurol 53:513-520.
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 513-520
    • Golden, J.A.1    Hyman, B.T.2
  • 19
    • 0001360461 scopus 로고
    • Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
    • Griffin WST, Stanley LC, Ling C et al. (1989): Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc Natl Acad Sci USA 86:7611-7615.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7611-7615
    • Griffin, W.S.T.1    Stanley, L.C.2    Ling, C.3
  • 20
    • 0016745165 scopus 로고
    • Systematic approach to the study of trisomy in the mouse II
    • Gropp A, Kolbus U, Giers D (1975): Systematic approach to the study of trisomy in the mouse II. Cytogenet Cell Genet 14:42-62.
    • (1975) Cytogenet Cell Genet , vol.14 , pp. 42-62
    • Gropp, A.1    Kolbus, U.2    Giers, D.3
  • 22
    • 0028232799 scopus 로고
    • Transgenic mouse brain histopathology resembles early Alzheimer's disease
    • Higgins LS, Holtzman DM, Rabin J et al. (1994): Transgenic mouse brain histopathology resembles early Alzheimer's disease. Ann Neurol 35:598-607.
    • (1994) Ann Neurol , vol.35 , pp. 598-607
    • Higgins, L.S.1    Holtzman, D.M.2    Rabin, J.3
  • 23
    • 0026569335 scopus 로고
    • Dysregularion of gene expression in mouse trisomy 16, an animal model of Down syndrome
    • Holtzman DM, Bayney RM, Li Y et al. (1992a): Dysregularion of gene expression in mouse trisomy 16, an animal model of Down syndrome. EMBO J 11:619-627.
    • (1992) EMBO J , vol.11 , pp. 619-627
    • Holtzman, D.M.1    Bayney, R.M.2    Li, Y.3
  • 24
    • 0029448075 scopus 로고
    • Preliminary characterization of the nervous system in partial trisomy 16 mice
    • Epstein CJ (ed): New York: John Wiley & Sons
    • Holtzman DM, Kilbridge J, Chen KS et al. (1995): Preliminary characterization of the nervous system in partial trisomy 16 mice. In Epstein CJ (ed): Etiology and Pathogenesis of Down Syndrome. New York: John Wiley & Sons, pp 227-240.
    • (1995) Etiology and Pathogenesis of Down Syndrome , pp. 227-240
    • Holtzman, D.M.1    Kilbridge, J.2    Chen, K.S.3
  • 25
    • 0027742330 scopus 로고
    • Nerve growth factor reverses neuronal atrophy in a Down syndrome model of neurodegeneration
    • Holtzman DM, Li Y, Chen K et al. (1993): Nerve growth factor reverses neuronal atrophy in a Down syndrome model of neurodegeneration. Neurology 43:2668-2673.
    • (1993) Neurology , vol.43 , pp. 2668-2673
    • Holtzman, D.M.1    Li, Y.2    Chen, K.3
  • 26
    • 0026593199 scopus 로고
    • A mouse model of neurodegeneration: Atrophy of basal forebrain neurons in Ts 16 transplants
    • Holtzman DM, Li Y, DeAnnond SJ et al. (1992b): A mouse model of neurodegeneration: Atrophy of basal forebrain neurons in Ts 16 transplants. Proc Natl Acad Sci USA 89:1383-1387.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1383-1387
    • Holtzman, D.M.1    Li, Y.2    DeAnnond, S.J.3
  • 27
    • 0026086869 scopus 로고
    • Molecular studies in Alzheimer's disease
    • Holtzman DM, Mobley WC (1991): Molecular studies in Alzheimer's disease. Trends Biochem Sci 16:140-144.
    • (1991) Trends Biochem Sci , vol.16 , pp. 140-144
    • Holtzman, D.M.1    Mobley, W.C.2
  • 28
    • 0028847995 scopus 로고
    • Charcot-Marie-Tooth neuropathies: From clinical description to molecular genetics
    • lonasescu W (1995): Charcot-Marie-Tooth neuropathies: From clinical description to molecular genetics. Muscle Nerve 18:267-275.
    • (1995) Muscle Nerve , vol.18 , pp. 267-275
    • Lonasescu, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.