Effect of ginger (Zingiber officinale R.) on lipids in rats fed atherogenic diet

Journal of Clinical Biochemistry and Nutrition

Volumn 27, Issue 2, 1999, Pages 79-87

  Murugaiah, Jeyakumar Shanmugam ^a   Namasivayam, Nalini ^a   Menon, Venugopal Padmanabhan ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Atherosclerosis; Ginger; High fat diet; Lipids; Lipoproteins

Indexed keywords

EID: 0002873426     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.27.79     Document Type: Article

References (30)

1. Duguid, J.B. (1946): Thrombosis as a factor in the pathogenesis of coronary atherosclerosis. J. Pathol. Bacteriol., 58, 207-212.
2. Schwartz, C.J., Valente, A.J., and Sprague, E.A. (1993): A modern view of atherogenesis. Am. J. Cardiol., 71, 9B-14B.
3. La Rosa, J.C., Hunninghake, D., and Bush, D. (1990): The cholesterol facts; A summary of the evidence relating dietary fats, serum cholesterol and CHD. A Joint Statement by the American Heart Association and the National Heart, Lung and Blood Institute. Circulation, 81, 1721-1733.
4. Huttunen, J.K., Manninen, V., and Manttari, M. (1991): The Helsinki Heart Study, central findings and clinical implication. Ann. Med., 53, 155-159.
5. Ahmed, R.S., and Sharma, S.B. (1997): Biochemical studies of combined effect of garlic (Allium sativum L.) and ginger (Zingiber officinale Rosc) in albino rats. Indian J. Exp. Biol., 35, 841-843.
6. Srivastava, K.C., and Mustafa, T. (1992): Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med. Hypotheses, 39, 342-348.
7. Yoshikawa, M., Yamaguchi, S., Kunimi, K., Matsuda, H., Okuno, Y., Yamahara, J., and Murakami, N. (1994): Stomachic principles in ginger. III. An anti-ulcer principle, 6-gingesulfonic acid, and three monoacyldigalactosylglycerol, gingerglycolipids A, B and C, from Zingiberis Rhizoma originating in Taiwan. Chem. Pharm. Bull. Tokyo, 42, 1226-1230.
8. Phillips, S., Ruggier, R., and Hutchinson, S.E. (1993): Zingiber officinale (ginger) - An antiemetic for day case surgery. Anaesthesia, 48, 715-717.
9. Srinivasan, K., and Sambaiah, K. (1991): The effect of spices on cholesterol 7α-hydroxylase activity and on serum and hepatic cholesterol levels in the rats. Int. J. Vit. Nutr. Res., 61, 364-369.
10. Zlatkis, A., Zak, B., and Boyle, A.J. (1953): A new method for the direct determination of serum cholesterol. J. Lab. Clin. Med., 45, 486-493.
11. Zilversmit, B., and Davis, A.K. (1950): Microdetermination of plasma phospholipids by trichloroacetic acid precipitation. J. Lab. Clin. Med., 35, 155-160.
12. Falholt, K., Falholt, W., and Lund, B. (1973): An easy colorimetric method for routine determination of free fatty acids in plasma. Clin. Chim. Acta, 46, 105-111.
13. Fossati, P., and Lorenzo, P. (1982): Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin. Chem., 29, 2077-2080.
14. Mc Gowan, M.W., Artiss, J.D., Stranberg, D.R., and Zak, B.A. (1983): Peroxidase coupled method for the colorimetric determination of serum triglycerides. Clin. Chem., 29, 538-542.
15. Lopes, V. (1977): Cholesterol determination in HDL separated by three different methods. Clin. Chem., 23, 882-886.
16. Allain, C.C. (1974): Determination of serum cholesterol. Clin. Chem., 20, 470-475.
17. Folch, J., Lees, M., and Stanly, G.H.S. (1957): A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem., 226, 297-309.
18. Chou, Y.L. (1975): Experimental design and the analysis of variance, in Statistical Analysis, Holt, Rinehart and Winston Publication, New York, pp. 340-355.
19. Tanabe, M., Chen, Y.D., Saito, K., and Kano, Y. (1993): Cholesterol biosynthesis inhibitory component from Zingiber officinale Roscoe. Chem. Pharm. Bull., 41, 710-713.
20. Whereat, A.F., and Rabinowitz, J.L. (1975): Aortic mitochondrial synthesis of lipid and its response to cholesterol feeding. Am. J. Cardiol., 35, 567-569.
21. Mirhadi, S.A., Sundarshan Singh, and Gupta, P.P. (1991): Effect of garlic supplementation to cholesterol rich diet on development of atherosclerosis in rabbits. Indian J. Exp. Biol., 29, 162-168.
22. Manimegalai, R., Geetha, A., and Rajalakshmi, K. (1993): Effect of vitamin E on high fat diet induced hyperlipidemia in rats. Indian J. Exp. Biol., 31, 704-707.
23. Srinivasan, M.R., and Satyanarayana, M.N. (1989): Effect of capsaicin on skeletal muscle lipoprotein lipase in rats fed high fat diet. Inidan J. Exp. Biol., 27, 910-912.
24. Parathasarathy, S., Quinn, M.T., and Schwenke, D.C. (1989): Oxidative modification of beta-very low density lipoprotein potential role in monocyte recruitment and foam cell formation. Atherosclerosis, 9, 393-399.
25. Jurgens, G., Lang, J., Esterbauer, H., and Holasek, A. (1984): Modification of human low density lipoprotein by 4-hydroxy nonenal IRCS. Med. Sci., 12, 252-253.
26. Cao, Z.F., Chen, Z.G., Guo, P., Zhang, S.M., Lian, L.X., Luo, L., and Hu, W.M. (1993): Scavenging effects of ginger on superoxide anion and hydroxyl radical. Chung-Kuo-Chung-Yao-Tsa-Chih, 18, 750-754, 764.
27. Liu, J., and Xiao, P.G. (1994): Recent advances in the study of antioxidative effects of Chinese medicinal plants. Phytother. Res., 8, 445-457.
28. Miller, G.L., and Miller, N.E. (1975): Plasma high density lipoprotein concentration and development of ischaemic heart disease. Lancet, 1, 16-19.
29. Gordon, T. (1977): High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am. J. Med., 62, 707-714.
30. Miller, N.E., Thelle, D.S., Forde, O.H., and Mjos, O.D. (1977): The Tromso heart study. High density lipoprotein and coronary heart-disease: A prospective case-control study. Lancet, 1, 965-987.