Aging and Alzheimer's disease in Down syndrome: Clinical and pathological changes

Mental Retardation and Developmental Disabilities Research Reviews

Volumn 2, Issue 2, 1996, Pages 73-79

  Zigman, Warren ^a   Silverman, Wayne ^a   Wisniewski, Henryk M ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Aging; Alzheimer's disease; Down syndrome

Indexed keywords

EID: 0002849850     PISSN: 10804013     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1098-2779(1996)2:2<73::aid-mrdd3>3.3.co;2-d     Document Type: Article

References (19)

1. Aylward EH, Burt DB, Thorpe LU et al. (1995): Diagnosis of Dementia in Individuals With Intellectual Disability. Washington: American Association on Mental Retardation.
2. American Psychiatric Association (1994): Diagnostic and Statistical Manual of Mental Disorders, 4th edition. Washington, DC, pp 133-143.
3. Ball MJ, Nuttall K (1980): Neurofibrillary tangles, granulovacuolar degeneration, and neuron loss in Down syndrome: Quantitative comparison with Alzheimer dementia. Ann Neurol 7:462-465.
4. Brown WT (1985): Genetics of aging. In Janicki MP, Wisniewski HM (eds): Aging and Developmental Disabilities: Issues and Approaches. Baltimore: Brookes, pp 185-194.
5. Burger PC, Vogel F (1973): The development of pathologic changes of Alzheimer's disease and senile dementia in patients with Down syndrome. Am J Pathol 73:457-468.
6. Burt DB, Loveland KA, Chen YW et al. (1995): Aging in adults with Down syndrome: Report from a longitudinal study. Am J Ment Retard 100:262-270.
7. Burt DB, Loveland KA, Lewis KR (1992): Depression and the onset of dementia in adults with mental retardation. Am J Ment Retard 96:502-511.
8. Carter G, Jancar J (1983): Mortality in the mentally handicapped: A 50 year survey at the Stokes Park group of hospitals. J Ment Defic Res 27:143-156.
9. Cohen GD (1983): Historical views and evolution of concepts. In Reisberg B (ed): Alzheimer's Disease: The Standard Reference. New York: The Free Press, pp 29-33.
10. Collacott RA (1993): Epilepsy, dementia and adaptive behaviour in Down's syndrome. J Intellect Disabil Res 37:153-160.
11. Cummings JL (1994): Dementia: The failing brain. Lancet 345:1481-1484.
12. Devenny DA, Hill AL, Patxot O et al. (1992): Ageing in higher functioning adults with Down's syndrome: An interim report in a longitudinal study. J Intellect Disabil Res 36:241-250.
13. Devenny DA, Silverman WP (1990): Speech dysfluency and manual specialization in Down's syndrome. J Ment Defic Res 34:253-260.
14. Durkin MS, Schupf N, Stein ZA et al. (1994): Epidemiology of mental retardation. In Levene M, Lifford R (eds): Fetal and Neonatal Neurology and Neurosurgery, 2nd edition. London: Churchill. Livingston, pp 689-706.
15. Ellis WG, McCulloch JR, Corley CL (1974): Presenile dementia in Down's syndrome. Neurology 24:101-106.
16. Epstein CJ (1986): Trisomy 21 and the nervous system: From cause to cure. In Epstein CJ (ed): The Neurobiology of Down Syndrome. New York: Raven Press, pp 1-15.
17. Evans DA (1990): Estimated prevalence of Alzheimer's disease in the United States. Milbank Q 68:267-289.
18. Evenhuis HM (1990): The natural history of dementia in Down's syndrome. Arch Neurol 47:263-267.
19. Fenner ME, Hewitt KE, Torpy DM (1987): Down's syndrome: Intellectual and behavioral functioning during adulthood. J Ment Defic Res 31:241-249.