Enzymatic cleavage of N-phenylacetyl-protected ethanolamine phosphates

Liebigs Annales

Volumn , Issue 6, 1997, Pages 1215-1220

  Van Straten, Nicole C R ^a   Duynstee, Howard I ^a   De Vroom, Erik ^b   Van Der Marel, Gijsbert A ^a   Van Boom, Jacques H ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Gist Brocades NV   (Netherlands)

Author keywords

Carbohydrates; Ethanolamine phosphates; Glucosylations; L glycero D mamo Heptopyranosides; Phenylacetyl, enzymatic cleavage

Indexed keywords

EID: 0002806997     PISSN: 09473440     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlac.199719970625     Document Type: Article

References (15)

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12. We recently reported the N-PhAc protection of a tyramine spacer in the synthesis of a tetrameric fragment of the cell-wall phenolic glycolipids of Mycobacterium kansasii, serovar 1 (K. Zegelaar-Jaarsveld, S. A. W. Smits, N. C. R. van Straten, G. A. van der Marel, J. H. van Boom, Tetrahedron 1996, 52, 3593).
13. 2-(Phenylacetylamino)ethanol was prepared from ethanolamine and phenylacetyl chloride under Schotten-Baumann conditions in 70 % yield.
14. Immobilized penicillin-G acylase is available from Gist-brocades B.V. under the name Separase G® (E. C. 3.5.1.11).
15. H. I. Duynstee, personal communication.