Cellular rejection of fetal pancreas grafts: Differences between allo- And xenograft rejection

Xenotransplantation

Volumn 4, Issue 1, 1997, Pages 2-10

  Mandel, T E ^a,b   Kovarik, J ^a   Koulmanda, M ^a   Georgiou, H M ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Eosinophils; Histopathologic features; Hyperacute rejection

Indexed keywords

EID: 0002779427     PISSN: 0908665X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3089.1997.tb00158.x     Document Type: Review

References (57)

1. BACH FH, ROBSON SC, WINKLER H, FERRAN C, STUHLMEIER KM, WRIGHTON CJ, HANCOCK WW. Barriers to xenotrans-plantation. Nat Med 1995:1:869-873.
2. BACH FH, ROBSON SC, FERRAN C, WINKLER H, MILLAN MT, STUHLMEIER KM, VANHOVE B, BLAKELY ML, VAN DER WERF WJ, HOFER E, DEMARTIN R, HANCOCK WW. Endothelial cell activation and thromboregulation during xenograft rejection. Immunol Rev 1994:141:5-30.
3. LAWSON JH, PLATT JL. Molecular barriers to xenotransplantation. Transplantation 1996:62:303-310.
4. MOSES RD, PIERSON RN III, WINN HJ, AUCHINCLOSS H Jr. Xenogeneic proliferation and lymphokine production are dependent on CD4+ helper T cells and self antigen-presenting cells. J Exp Med. 1990:172:567-575.
5. MOSES RD, WINN HJ, AUCHINCLOSS H Jr. Evidence that multiple defects in cell-surface molecule interactions across species differences are responsible for diminished xenogeneic T cell responses. Transplantation 1992:53:203-209.
6. YAMADA K, SACHS DH, DERSIMONIAN H. Human anti-porcine Xenogeneic T cell response: Evidence for allelic specificity of mixed lymphocyte reaction and for both direct and indirect pathways of recognition. J Immunol 1995:155:5249-5256.
7. MURRAY AG, KHODADOUST MM, POBER JS, BOTHWELL AL. Porcine aortic endothelial cells activate human T cells: direct presentation of MHC antigens and costimulation by ligands for human CD2 and CD28. Immunity 1994:1:57-63.
8. AUCHINCLOSS H Jr. Xenotransplantation: A review. Transplantation 1988:46:1-20.
9. KAUFMAN CL, GAINES BA, ILDSTADT ST. Xenotransplantation. Annu Rev Immunol 1995:13:339-367.
10. MCKENZIE IFC, KOULMANDA M, SANDRIN MS, MANDEL TE. The expression of Gal α(1-3) Gal by porcine islet cells and its relevance to xenotransplantation. Xenotransplantation 1995:2:139-142.
11. MCKENZIE IFC, KOULMANDA M, MANDEL TE, XING P-X, SANDRIN MS. Pig to human xenotransplantation: the expression of Gal α(1-3) gal epitopes on pig islet cells. Xenotransplantation 1995:2:1-7.
12. KOULMANDA M, MCKENZIE IFC, SANDRIN MS, MANDEL TE. Fetal pig islet xenografts in NOD/Lt mice: The effect of peri-transplant anti-CD4 monoclonal antibody and graft immunomodification on graft survival, and lack of expression of Gal (α1-3) Gal on endocrine cells. Xenotransplantation 1995:2:295-305.
13. THOMPSON SC, MANDEL TE. Fetal Pig Pancreas: Preparation and assessment of tissue for transplantation, its in vivo development and function in athymic (nude) mice. Trans-plantation: 1990:49:571-581.
14. GALILI U. Interaction of the natural anti-Gal antibody with alpha-galactosyl epitopes: A major obstacle for xenotransplantation in humans. Immunol Today 1993: 14:480-482.
15. BAXTER AG, COOKE A. Complement lytic activity has no role in the pathogenesis of autoimmune diabetes in NOD mice. Diabetes 1993:42:1574-1578.
16. MANDEL TE, KOVARIK J, KOULMANDA M. A comparison of organ cultured fetal pancreas allo-, iso- and xenografts (pig) in non-immunosuppressed non-obese diabetic (NOD) mice. Am J Pathol 1995:147:834-844.
17. WALLGREN AC, KARLSSON-PARRA A, RIDDERSTAD A, KURSGREN O. The main infiltrating cell in xenograft rejection is a CD4+ macrophage and not a T lymphocyte. Transplantation 1995:60:594-601.
18. KARLSSON-PARRA A, RIDDERSTAD A, WALLGREN AC, MOLLER E, LJUNGGREN HG, KORSGREN O. Xenograft rejection of porcine islet-like cell clusters in normal and natural killer cell-depleted mice. Transplantation 1996:61:1313-1320.
19. FAUSTMAN D, COE C. Prevention of xenograft rejection by masking donor HLA class I antigens. Science 1991:252:1700-1702.
20. LENSCHOW DJ, ZENG Y, THISTLETHWAITE JR, MONTAG A, BRADY W, GIBSON MG, LINSLEY PS, BLUESTONE JA. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA41g. Science 1992:257:789-792.
21. SIMEONOVIC CJ, CEREDIG R, WILSON JD. Effect of GK1.5 monoclonal antibody dosage on survival of pig proislet xenografts in CD4+ T cell-depleted mice. Transplantation 1990:49:849-856.
22. MANDEL TE, KOULMANDA M, BACELJ A. Fetal pancreas transplantation in non-obese diabetic (NOD) mice: A com-parison of iso, allo-, and xenografts. Horm Metab Res 1990: (Suppl) 25:166-173.
23. MANDEL TE, KOULMANDA M, LOUDOVARIS T, BACELJ A. Xenografts of Fetal pig islets in NOD mice: Recurrence of disease and rejection of allografts precedes xenograft rejection in anti-CD-4 treated mice. In: Shafrir E, ed. Lessons from animal diabetes, III. 1990:120-125.
24. PIERSON RN, WINN HJ, RUSSELL PS, AUCHINCLOSS H Jr. Xenogeneic skin graft rejection is especially dependent on CD4+ T cells. J Exp Med 1989:170:991-996.
25. O'CONNELL PJ, PACHECO-SILVA A, NICKERSON PW, MUGGIA RA, BALTOS M, KELLEY VR, STROM TB. Unmodified pancreatic islet allograft rejection results in the preferential expression of certain T cell activation transcripts. J Immunol 1993:150:1093-1104.
26. MORRIS CF, SIMEONOVIC CJ, FUNG MC, WILSON JD, HAPEL AJ. Intragraft expression of cytokine transcripts during pig proislet xenograft rejection and tolerance. J Immunol 1995:154:2470-2482.
27. KOVARIK J, KOULMANDA M, MANDEL TE. The expression of pro-inflammatory factors in fetal pig pancreas xenografts compared to BALB/c allografts in NOD mice. Transplantation (submitted).
28. MANDEL TE, KOULMANDA M, KOVARIK J, GEORGIOU HM, FRANCIS DMA, DAWSON P, STAINSBY G. Transplantation of organ cultured fetal pig pancreas in non-obese diabetic (NOD) mice and primates (Macaca fascicularis). Xenotransplantation 1995:2:128-132.
29. MANDEL TE, KOULMANDA M, COZZI E, WATERWORTH P, TOLAN M, LANGFORD G, WHITE DJG. Transplantation of normal and DAF-transgenic fetal pig pancreas into cynomolgus monkeys, Transpl Proc (in press).
30. WEIR MR, HALL-CRAGGS M, SHEN SY, POSNER JN, ALONGI SV, DAGHER FJ, SADLER JH. The prognostic value of the eosinophil in acute renal allograft rejection. Transplantation 1986:41:709-712.
31. KORMENDI F, AMEND WJC. The importance of eosinophil cells in kidney allograft rejection. Transplantation 1988:45:537-539.
32. FOSTER PF, SANKARY HN, HART M, ASHMANN M, WILLIAMS JW. Blood and graft eosinophilia as predictors of rejection in human liver transplantation. Transplantation 1989:47:72-74.
33. HALLGREN R, BOHMAN SO, FREDENS K. Activated eosinophil infiltration and deposits of eosinophil cationic protein in renal allograft rejection. Nephron 1991:59:266-270.
34. WANG H, NANDRA RS, STEIN A, Avis L, PRICE A, HIBBERD AD. Eosinophils in acute renal allograft rejection. Transpl Immunol 1994:2:41-46.
35. MARTINEZ OM, ASCHER NL, FERRELL L, VILLAUEVA J, LAKE J, ROBERTS JP, KRAMS SM. Evidence for a nonclassical pathway of graft rejection involving interleukin 5 and eosinophils. Transplantation 1993:55:909-918.
36. DE GROEN PC, KEPHART GM, GLEICH GJ, LUDWIG J. The eosinophil as an effector cell of the immune response during hepatic allograft rejection. Hepatology 1994:20:654-662.
37. SIMEONOVIC CJ, WILSON JD. Xenotransplantation of fetal pig proislets in anti-CD4-treated diabetic NOD mice. Transplant Proc 1992:24:2287-2288.
38. SILBERSTEIN DS, DAVID JR. The regulation of human eosinophil function by cytokines. Immunol Today 1987:8:380-385.
39. + T cells, IL5, and mast cells. Clin Immunol Immunopathol 1994:73:305-311.
40. WELLER PF. Cytokine regulation of eosinophil function. Clin Immunol Immunopathol 1992:62:855-59.
41. WARDLAW AJ. Eosinophils in the 1990s: new perspectives on their role in health and disease. Postgrad Med J 1994:70:536-552.
42. KROEGEL C, WARNER JA, VIRCHOW J-C Jr, MATTHYS H. Pul-monary immune cells in health and disease: the eosinophil leucocyte (part II). Eur Respir J 1994:7:743-760.
43. TEPPER RI, COFFMAN RL, LEDER P. An eosinophil-depen-dent mechanism for the antitumor effect of interleukin-4. Science 1992:257:548-551.
44. TEPPER RI, PATTENGALE PK, LEDER P. Murine interleukin-4 displays anti-tumor activity in vivo. Cell 1989:57:503-512.
45. SHER A, OTTENSEN E. Immunoparasitology. In Immunological diseases, 4th ED. Samter M, Talmage DW, Frank MM, Austen KF, Claman HN, eds. Boston: Little, Brown and Co., 1988:923.
46. KROEGEL C, VIRCHOW J-C Jr, LUTTMANN W, WALKER C, WARNER JA. Pulmonary immune cells in health and disease: The eosinophil leucocyte (Part I). Eur Respir J 1994:7:519.
47. SIMEONOVIC C, WILSON J, RAMSAY A. Role of IL-4 in pig proislet xenograft rejection in mice. Transpl Proc 1995:27:3571.
48. MANDEL TE, DILLON H, KOULMANDA M. The effect of a depleting anti-CD4 monoclonal antibody on T cells and fe-tal pig islet xenograft survival in various strains of mice. Transpl Immunol 1995:3:265-272.
49. NOGUCHI H, KEPHART GM, COLBY TV, GLEICH GL. Tissue eosinophilia and eosinophil degranulation in syndromes associated with fibrosis. Am J Pathol 1992:140:521-528.
50. ROHRBACH MS, WHEATLEY CL, SLIFMAN NR, GLEICH GJ. Activation of platelets by eosinophil granule proteins. J Exp Med 1990:172:1271-1274
51. BARCLAY AN. The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. Immunology 1981:42:593-600.
52. LUCEY DR, DORSKY DI, NICHOLSON-WELLER A, WELLER PF. Human eosinophils express CD4 protein and bind human immunodeficiency virus-1 gp120. J Exp Med 1989:169:3278-332.
53. INVERARDI L, SAMAJA M, MOTTERLINI R, MANGILI F, BENDER JR, PARDI R. Early recognition of a discordant xenogeneic organ by human circulating lymphocytes. J Immunol 1992:149:1416-1423.
54. MALYGUINE AM, SAADI S, PLATT JL, DAWSON JR. Human natural killer cells induce morphologic changes in porcine endothelial cell cultures. Transplantation 1996:61:161-164.
55. GOODMAN DJ, VON ALBERTINI M, WILLSON A, MILLAN MT, BACH FH. Direct activation of porcine endothelial cells by human natural killer cells. Transplantation 1996:61:763-771.
56. SEEBACH JD, YAMADA K, MCMORROW IM, SACHS DH, DERSIMONIAN HD. Xenogeneic human anti-pig cytotoxicity mediated by activated killer cells. Xenotransplantation 1996:3:188-197.
57. MARCUS H, FACTOROVICH Y, KULOVA L, SEGAL H, DAVID M, BURAKOVA T, REISNER Y. Allograft and xenograft rejection in C3H/SCID mice. A new model for the study of non-T cell graft rejection mechanisms. Transplantation 1996:61:777-783.