Intraovarian growth factors and follicular development

Current Opinion in Endocrinology and Diabetes

Volumn 3, Issue 6, 1996, Pages 478-482

  Udoff, Laurence C ^a   Adashi, Eli Y ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002743880     PISSN: 10683097     EISSN: None     Source Type: Journal    
DOI: 10.1097/00060793-199612000-00005     Document Type: Article

References (44)

1. Murphy LJ, Bell GI, Friesen HG: Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat Endocrinology 1987, 120:1279-1282.
2. Hernandez ER, Roberts CH, LeRoith D, Adashi EY: Rat ovarian insulin-like growth factor I gene expression is granulosa cell-sensitive: 5′ untranslated mRNA variant representation and hormonal regulation. Endocrinology 1989, 125:572-574.
3. Carlsson B, Carlsson L, Billig H: Estrus cycle-dependent co-variation of insulin-like growth factor I messenger ribonucleic acid and protein in the rat ovary. Mol Cell Endocrinol 1989, 64:271-275.
4. Adashi EY, Resnick CE, Hernandez ER, Svoboda ME, Van Wyk JJ: Characterization and regulation of a specific cell membrane receptor for somatomedin-C/insulin-like growth factor I in cultured rat granulosa cells. Endocrinology 1988, 122:194-201.
5. Adashi EY, Resnick CE, Svoboda ME, Van Wyk JJ: Follicle-stimulating hormone enhances somatomedin-C binding to cultured rat granulosa cells: evidence for cAMP-dependence. Endocrinology 1986, 261:3923-3926.
6. Adashi EY, Resnick CE, Svoboda ME, Van Wyk JJ: In vivo regulation of granulosa cells somatomedin-C/insulin-like growth factor I receptors. Endocrinology 1988, 122:1383-1389.
7. Davoren JB, Kasson BG, Li CH, Hsuch AJW: Specific insulin-like growth factor I and II binding sites on rat granulosa cells. Relation to IGF action. Endocrinology 1986, 119:2155-2162.
8. Adashi EY, Resnick CE, Rosenfeld RD: Insulin-like growth factor I and IGF-II hormonal action in cultured rat granulosa cells: mediation via I but not II IGF receptors. Endocrinology 1990, 126:216-222.
9. Adashi EY, Resnick CE, Svoboda ME, Van Wyk JJ: Somatomedin-C synergizes with follicle stimulating hormone in the acquisition of progesterone biosynthetic capacity by cultured rat granulosa cells. Endocrinology 1985, 116:2135-2142.
10. Adashi EY, Resnick CE, Brodie AMH, Svoboda ME, Van Wyk JJ: Somatomedin-C mediated potentiation of follicle stimulating hormone aromatase activity of cultured rat granulosa cells. Endocrinology 1985, 117:2313-2320.
11. Adashi EY, Resnick CE, Brodie AMH, Svoboda ME, Van Wyk JJ: Somatomedin-C enhances induction of luteinizing hormone receptors by follicle-stimulating hormone in cultured rat granulosa cells. Endocrinology 1985, 116:2369-2375.
12. Cara JF: Insulin-like growth factors, insulin-like growth factor binding proteins, and ovarian androgen production. Horm Res 1994, 42:49-54.
13. Baker J, Hardy MP, Zhou J, Bondy C, Lupu F, Bellvé AR, Efstratiadis A: Effects of an Igf1 gene null mutation on mouse reproduction. Mol Endocrinol 1996, 10:903-918. This study provides support for the concept that IGF-I is a necessary component in the process of follicular growth and maturation. In mice with a null mutation for the IGF-I gene, spontaneous ovulation does not occur and cannot be induced with physiologic stimuli.
14. Efstratiadis A: IGFs and dwarf mice: genetic and epigenetic control of embryonic growth. In Frontiers in Endocrinology: Developmental Endocrinology. Edited by Sizonenko PC, Aubert ML, Vassalli JD. Rome, Italy: Ares-Serono Symposai; 1994:27-42.
15. Matthews CH, Borgato S, Beck-Peccoz P, Adams M, Tone Y, Gambino G, Casagrande S, Tedeschini G, Benedetti A, Chatterjee VK: Primary amenorrhoea and infertility due to a mutation in the beta-subunit of follicle-stimulating hormone. Nat Genet 1993, 5:83-86.
16. El-Roeiy A, Chen X, Roberts VJ, LeRoith D, Roberts CT, Yen SS: Expression of insulin-like growth factor-I (IGF-I) and IGF-II and the IGF-I, IGF-II, and insulin receptor genes and localization of the gene products in the human ovary. J Clin Endocrinol Metab 1993, 77:1411-1418.
17. Yoshimura Y, Nagamatsu S, Ando M, Iwashita M, Oda T, Katsumata Y, Shiokawa S, Nakamura Y: Insulin-like growth factor binding protein-3 inhibits gonadotropin-induced ovulation, oocyte maturation, and steroidogenasis in rabbit ovary. Endocrinology 1996, 137:438-446. This study utilized an ex vivo perfused rabbit ovary system to document that IGF-I stimulates follicular growth, oocyte maturation, and estradiol production. IGF binding protein-3 added to the perfusate inhibits these effects as well as human chorionic gonadotropin-induced ovulation.
18. Zhou J, Refuerzo J, Bondy C: Granulosa cell DNA synthesis is strictly correlated with the presence of insulin-like growth factor I and absence of c-fos/c-jun expression. Mol Endocrinol 1995, 9:924-931. This study utilized in situ hybridization to demonstrate a strong positive correlation between granulosa cell IGF-I mRNA and follicular growth, suggesting that in vivo IGF-I functions as an autocrine effector supporting granulosa cell proliferation.
19. Maitra A, LaVoie HA, Day RN, Garmey JC, Veldhuis JD: Regulation of porcine granulosa cell 3-hydroxy-3-methylglutaryl coenzyme A reductase by insulin and insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist. Endocrinology 1995, 136:5111-5117.
20. Veldhuis JD, Gwynne JT, Strauss III JF, Demers LM: Role of estradiol as a biological amplifier of gonadotropin action in the ovary: in vitro studies using swine granulosa cells and homologous lipoproteins. Endocrinology 1984, 114:2312-2322.
21. Urban RJ, Veldhuis JD: Endocrine control of steroidogenesis in granulosa cells. Oxf Rev Reprod Biol 1992, 14:225-262.
22. Klein NA, Battaglia DE, Miller PB, Branigan EF, Giudice LC, Soules MR: Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age. J Clin Endocrinol Metab 1996, 81:1946-1951.
23. Giudice LC: Insulin-like growth factors and ovarian follicular development. Endocrin Rev 1992, 13:641-669.
24. Juul A, Bang P, Hertel NT, Main K, Dalgaard P, Jorgensen K, Muller J, Hall K, Skakkebaek NE: Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index. J Clin Endocrinol Metab 1994, 78:744-752.
25. Juul A, Main K, Blum WF, Lindholm J, Ranke MB, Skakkebaek NE: The ratio between serum levels of insulin-like growth factor (IGF)-I and the IGF binding proteins (IGFBP-1,2 and 3) decreases with age in healthy adults and is increased in acromegalic patients. Clin Endocrinol (Clin Oxf) 1994, 41:85-93.
26. Keefe DL, Niven-Fairchild T, Powell S, Buradagunta S: Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women. Fertil Steril 1995, 64:577-583.
27. Gordon JD, Mesiano S, Zaloudek CJ, Jaffe RB: Vascular endothelial growth factor localization in human ovary and fallopian tubes: possible role in reproductive function and ovarian cyst formation. J Clin Endocrinol Metab 1996, 81:353-359. This study utilized immunohistochemical analysis to demonstrate that VEGF is differentially expressed in healthy versus atretic follicles.
28. Gospodarowicz D, Abraham JA, Schilling J: Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculostellate cells. Proc Natl Acad Sci USA 1989, 86:7311-7315.
29. Keck PJ, Hauser SD, Krivi G: Vascular permeability factor, an endothelial cell mitogen related to PDGF. Science 1989, 246:1309-1312.
30. Leung D, Cachianes G, Kuang W: Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989, 246:1306-1309.
31. Ferrara N, Henzel WJ: Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989, 161:851-858.
32. Connolly DT: Vascular permeability factor: a unique regulator of blood vessel function. J Cell Biochem 1991, 47:219-223.
33. Senger DR, Van de Water L, Brown U, Nagy JA, Yeo KT, Yeo TK, Bers B, Jackman RW, Dvorak AM, Dvorak HF: Vascular permeability factor (VPF, VEGF) in tumor biology. Cancer Metastasis Rev 1993, 12:303-324.
34. Roberts AB, Sporn MB: The transforming growth factor-βs. In Peptide Growth Factors and Their Receptors. Edited by Sporn MB, Roberts AB. Heildenberg: Springer-Verlag; 1990:419-472.
35. Massague J: The transforming growth factor β family. Annu Rev Cell Biol 1990, 6:597-641.
36. Skinner MK, Osteen KG, Moses HL: Ovarian theca cells produce transforming growth factor-β which can regulate granulosa cell growth. Endocrinology 1987, 121:786-792.
37. Mulheron GW, Danielpour D, Schomber DW: Rat thecal-interstitial cells express transforming growth factor-β type 1 and 3, but only type 2 is regulated by gonadotropin in vitro. Endocrinology 1991, 129:368-374.
38. Teerds KJ, Dorrington JG: Immunohistochemical localization of transforming growth factor-β1 and -β2 during follicle development in the adult rat ovary. Mol Cell Endocrinol 1992, 84:R7-R13.
39. Schmid P, Cox D, van der Putten H, McMaster GK, Bilbe G: Expression of TGF-βs and TGF-β type II receptor mRNAs in mouse folliculogenesis: stored maternal TGF-β 2 message in oocytes. Biochem Biophys Res Commun 1994, 201:649-656.
40. Adashi EY, Resnick CE: Antagonistic interactions of transforming growth factors in the regulation of granulosa cell differentiation. Endocrinology 1986, 119:1879-1881.
41. Dodson WC, Schomber DW: The effect of transforming growth factor-β on follicle-stimulating hormone-induced differentiation of cultured rat granulosa. Endocrinology 1989, 120:512-517.
42. Magoffin DA, Gancedo B, Erickson GF: Transforming growth factor-β promotes differentiation of ovarian thecal-interstitial cells but inhibits androgen production. Endocrinology 1989, 125:1951-1958.
43. Dorrington JH, Bendell JJ, Khan SA: Interactions between FSH, estradiol-17β and transforming growth factor-β regulate growth and differentiation in the rat gonad. J Steroid Biochem Mol Biol 1993, 44:441-447.
44. Roy SK, Kole AR: Transforming growth factor-β receptor type II expression in the hamster ovary: cellular site(s), biochemical properties, and hormonal regulation. Endocrinology 1995, 136:4610-4162. This study demonstrates that the induction of TGF-β receptors in the hamster is influenced by gonadotropins and sex steroids, supporting the concept that TGF-β may play a physiologically revelant role in the process of follicular growth.