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Volumn 34, Issue 10, 1999, Pages 776-781

Characterization of hydroxylated metabolites of propafenone in healthy Chinese volunteers

Author keywords

Ion trap LC MSn; Metabolic hydroxylation; Microbial transformation; Propafenone

Indexed keywords

EID: 0002676514 PISSN: 05134870 EISSN: None Source Type: Journal
DOI: None Document Type: Article

Times cited : (3)

References (10)

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2
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- 2H-labelled propafenone in man
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- Microbial models of mammalian metabolism, biotransformations of HP 749 (besipirdine) using Cunninghamella elegans
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- Rao, G.P.¹ Davis, P.J.²

5
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- Stereoselective metabolism of rac-mexiletine by the fungus Cunninghamella echinulata yields the major human metabolites hydroxymethyl-mexiletine and p-hydroxymexiletine
- Freitag DG, Foster RT, Coutts RT, et al. Stereoselective metabolism of rac-mexiletine by the fungus Cunninghamella echinulata yields the major human metabolites hydroxymethyl-mexiletine and p-hydroxymexiletine. Drug Metab Dispos, 1997,25:685
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- Freitag, D.G.¹ Foster, R.T.² Coutts, R.T.³

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- Use of microorgnisms for the study of drug metabolism
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- Polymorphism of propafenone metabolism and disposition in man: Clinical and pharmacokinetic consequences
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- Siddoway, L.A.¹ Thompson, K.A.² McAllister, C.B.³

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- Low frequency of slow debrisoquine hydroxylation in a native Chinese population
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- Steady-state plasma kinetics of slow-release propafenone, its two isomers and its main metabolites
- Volz M, Mitrovic V, Thiemer J, et al. Steady-state plasma kinetics of slow-release propafenone, its two isomers and its main metabolites. Arzneimittel forsch/ Drug Res, 1995,45:246
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10
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- Enantioselective determination of propafenone and its metabolites in human plasma by liquid chromatography-mass spectrometry
- Zhong DF, Chen XY. Enantioselective determination of propafenone and its metabolites in human plasma by liquid chromatography-mass spectrometry. J Chromatogr B, 1999,721:67
- (1999) J Chromatogr B , vol.721 , pp. 67
- Zhong, D.F.¹ Chen, X.Y.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.