The first stereoselective bifunctionalization of 4-quinolones with organometallics and N-halosuccinimides to 2,3-trans disubstituted tetrahydroquinolones: Expected and unexpected results

Synlett

Volumn , Issue 6, 1998, Pages 649-651

  Beifuss, Uwe ^a   Feder, Gerald ^a   Bes, Teresa ^a   Usón, Isabel ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002672112     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1724     Document Type: Article

References (28)

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18. 4. The solvent was removed in vacuo and the residue was purified by flash chromatography on silica gel.
19. 13C NMR, IR, UV and MS) data were obtained for all new compounds. The yields are not optimized.
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25. 3: C, 57.77; H, 4.31. Found: C, 57.57; H 4.47.
26. Crystallographic data for 6a and 6b have been deposited with the Cambridge Crystallographic Data Centre.
27. 2 (5 mL) and the mixture was stirred for 10 min at rt.
28. Wakefield, B. J. Organomagnesium Methods in Organic Synthesis; Academic Press: London, 1995.