Pharmacokinetics of ampicillin/sulbactam in patients undergoing colorectal surgery: Measurements in serum, the colonic wall and in tissue at the incision site

International Journal of Antimicrobial Agents

Volumn 6, Issue SUPPL.1, 1996, Pages

  Wenzel, M ^a   Wildfeuer, A ^b   Gutsche, F ^a  

^a Behring Hospital Zehlendorf   (Germany)

^b PFIZER INC   (United States)

Author keywords

Ampicillin; Colorectal surgery; Sulbactam

Indexed keywords

EID: 0002556223     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(96)80006-9     Document Type: Article

References (6)

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3. Weigelt JA, Easley SM, Tahl ER, Palmer LD, Newman VS. Abdominal surgery wound infection is lowered with improved peri-operative enterococcus and bacteroides therapy. J Trauma 1993;34:579-585.
4. Retsema JA, English AR, Girard AE, Lynch JE, Anderson M, Brennan L, Cimochowski C, Faiella J, Norcia W, Sawyer P. Sulbactam/ ampicillin: in vitro spectrum, potency, and activity in models of acute infection. Rev Inf Dis 1986;8(suppl. 5):528-534.
5. Foulds G, Stankewich JP, Marshall DC, O'Brien MM, Hayes SL, Weidler DJ, McMahon FG. Pharmacokinetics of sulbactam in humans. Antimicrob Agents Chemother 1983;23:692-699.
6. Wildfeuer A, Müller V, Springsklee M, Sonntag HG. Pharmacokinetics of ampicillin and sulbactam in patients undergoing heart surgery. Antimicrob Agents Chemother 1991;35:1772-1776.