Comparison of Low-Shear and High-Shear Wet Granulation Techniques and the Influence of Percent Water Addition in the Preparation of a Controlled-Release Matrix Tablet Containing HPMC and a High-Dose, Highly Water-Soluble Drug

Pharmaceutical Technology

Volumn 20, Issue 3, 1996, Pages 80-92

  Sheskey, Paul J ^a   Williams, David M ^a  

^a DOW CHEMICAL COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002441970     PISSN: 01478087     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (9)

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6. C.D. Melia, "Hydrophilic Sustained Release Systems Based on Polysaccharide Carriers," Critical Reviews in Therapeutic Drug Carrier Systems 8, 395-421 (1991)
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8. L.W.S. Cheong, P.W.S. Heng, and L.F. Wong, "Relationship Between Polymer Viscosity and Drug Release from a Matrix System," Pharm. Res. 9, 1510-1514 (1992).
9. P.J. Sheskey et al., "Use of Roller Compaction in the Preparation of Controlled-Release Hydrophilic Matrix Tablets Containing Methylcellulose and Hydroxypropyl Methylcellulose Polymers," Pharm. Technol. 18 (9), 132-150 (1994).