-
1
-
-
0016287562
-
Dopamine receptor-block and nigral fiber-impulse blockade by major tranquilizers
-
Seeman, P., Wong, M., and Lee, T., Dopamine receptor-block and nigral fiber-impulse blockade by major tranquilizers, Fed. Proc., 33, 246, 1974.
-
(1974)
Fed. Proc.
, vol.33
, pp. 246
-
-
Seeman, P.1
Wong, M.2
Lee, T.3
-
2
-
-
0010686493
-
Brain receptors for antipsychotic drugs and dopamine: Direct binding assays
-
Seeman, P., Chau-Wong, M., Tedesco, J., and Wong, K., Brain receptors for antipsychotic drugs and dopamine: direct binding assays, Proc. Natl. Acad. Sci. U.S.A., 72, 4376, 1975.
-
(1975)
Proc. Natl. Acad. Sci. U.S.A.
, vol.72
, pp. 4376
-
-
Seeman, P.1
Chau-Wong, M.2
Tedesco, J.3
Wong, K.4
-
3
-
-
0017068246
-
Antipsychotic drug doses and neuroleptic/dopamine receptors
-
Seeman, P., Lee, T., Chau-Wong, M., and Wong, K., Antipsychotic drug doses and neuroleptic/dopamine receptors, Nature, 261, 717, 1976.
-
(1976)
Nature
, vol.261
, pp. 717
-
-
Seeman, P.1
Lee, T.2
Chau-Wong, M.3
Wong, K.4
-
4
-
-
0017094162
-
3H]dopamine binding associated with dopamine receptors in calf brain membranes
-
3H]dopamine binding associated with dopamine receptors in calf brain membranes, Mol. Pharmacol., 12, 800, 1976.
-
(1976)
Mol. Pharmacol.
, vol.12
, pp. 800
-
-
Burt, D.R.1
Creese, I.2
Snyder, S.H.3
-
5
-
-
0026481115
-
Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2, clozapine occupies D4
-
Seeman, P., Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2, clozapine occupies D4, Neuropsychopharmacology, 7, 261, 1992.
-
(1992)
Neuropsychopharmacology
, vol.7
, pp. 261
-
-
Seeman, P.1
-
6
-
-
0029612808
-
Therapeutic receptor-blocking concentrations of neuroleptics
-
Seeman, P., Therapeutic receptor-blocking concentrations of neuroleptics, Int. Clin. Psychopharmacol., 10 (Suppl. 3), 5, 1995.
-
(1995)
Int. Clin. Psychopharmacol.
, vol.10
, pp. 5
-
-
Seeman, P.1
-
7
-
-
0029841131
-
Dopamine and serotonin receptors: Amino acid sequences, and clinical role in neuroleptic Parkinsonism
-
Seeman, P., Corbett, R., Nam, D., and Van Tol, H.H.M., Dopamine and serotonin receptors: amino acid sequences, and clinical role in neuroleptic Parkinsonism, Jpn. J. Pharmacol., 71, 187, 1996.
-
(1996)
Jpn. J. Pharmacol.
, vol.71
, pp. 187
-
-
Seeman, P.1
Corbett, R.2
Nam, D.3
Van Tol, H.H.M.4
-
8
-
-
85049057557
-
Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4
-
Seeman, P., Corbett, R., and Van Tol, H.H.M., Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4, Neuropsychopharmacology, 16, 91, 1996.
-
(1996)
Neuropsychopharmacology
, vol.16
, pp. 91
-
-
Seeman, P.1
Corbett, R.2
Van Tol, H.H.M.3
-
9
-
-
0031953450
-
Antipsychotic drugs which elicit little or no Parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors
-
Seeman, P. and Tallerico, T., Antipsychotic drugs which elicit little or no Parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors, Mol. Psychiatry, 3, 123, 1998.
-
(1998)
Mol. Psychiatry
, vol.3
, pp. 123
-
-
Seeman, P.1
Tallerico, T.2
-
11
-
-
0029617261
-
CSF and serum concentrations of clozapine and its demethyl metabolite: A pilot study
-
Nordin, C., Almé, B., and Bondesson, U., CSF and serum concentrations of clozapine and its demethyl metabolite: a pilot study, Psychopharmacology, 122, 104, 1995.
-
(1995)
Psychopharmacology
, vol.122
, pp. 104
-
-
Nordin, C.1
Almé, B.2
Bondesson, U.3
-
12
-
-
0026718710
-
2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine
-
2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine, Arch. Gen. Psychiatry, 49, 538, 1992.
-
(1992)
Arch. Gen. Psychiatry
, vol.49
, pp. 538
-
-
Farde, L.1
Nordström, A.-L.2
Wiesel, F.-A.3
Pauli, S.4
Halldin, C.5
Sedvall, G.6
-
13
-
-
0028991822
-
2 receptor occupancy in relation to clozapine serum concentration: A PET study of schizophrenic patients
-
2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients, Am. J. Psychiatry, 152, 1444, 1995.
-
(1995)
Am. J. Psychiatry
, vol.152
, pp. 1444
-
-
Nordström, A.-L.1
Farde, L.2
Nyberg, S.3
Karlsson, P.4
Halldin, C.5
Sedvall, G.6
-
14
-
-
0029583353
-
Positron emission tomography studies on D2 dopamine receptor occupancy and plasma antipsychotic drug levels in man
-
Nyberg, S., Nordström, A.-L., Halldin, C., and Farde, L., Positron emission tomography studies on D2 dopamine receptor occupancy and plasma antipsychotic drug levels in man, Int. Clin. Psychopharmacol., 10 (Suppl. 3), 81, 1995.
-
(1995)
Int. Clin. Psychopharmacol.
, vol.10
, pp. 81
-
-
Nyberg, S.1
Nordström, A.-L.2
Halldin, C.3
Farde, L.4
-
15
-
-
0029026941
-
2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: A PET study
-
2 dopamine receptor occupancy of risperidone and its relationship to extrapyramidal symptoms: a PET study, Life Sci., 57, PL103, 1995.
-
(1995)
Life Sci.
, vol.57
, pp. PL103
-
-
Kapur, S.1
Remington, G.2
Zipursky, R.B.3
Wilson, A.A.4
Houle, S.5
-
16
-
-
0029946719
-
2 receptor occupancy with low-dose haloperidol treatment: A PET study
-
2 receptor occupancy with low-dose haloperidol treatment: a PET study, Am. J. Psychiatry, 153, 948, 1996.
-
(1996)
Am. J. Psychiatry
, vol.153
, pp. 948
-
-
Kapur, S.1
Remington, G.2
Jones, C.3
Wilson, A.4
DaSilva, J.5
Houle, S.6
Zipursky, R.B.7
-
17
-
-
0030300171
-
2 receptor occupancy profile of loxapine determined using PET
-
2 receptor occupancy profile of loxapine determined using PET, Neuropsychopharmacology, 15, 562, 1996.
-
(1996)
Neuropsychopharmacology
, vol.15
, pp. 562
-
-
Kapur, S.1
Zipursky, R.B.2
Jones, C.3
Remington, G.J.4
Wilson, A.A.5
DaSilva, J.6
Houle, S.7
-
18
-
-
0031595586
-
2 receptor occupancy of olanzapine in schizophrenia: A PET investigation
-
2 receptor occupancy of olanzapine in schizophrenia: a PET investigation, Am. J. Psychiatry, 155, 921, 1998.
-
(1998)
Am. J. Psychiatry
, vol.155
, pp. 921
-
-
Kapur, S.1
Zipursky, R.B.2
Remington, G.3
Jones, C.4
DaSilva, J.5
Wilson, A.A.6
Houle, S.7
-
19
-
-
0032982714
-
2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia
-
2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia, Am. J. Psychiatry, 156, 286, 1999.
-
(1999)
Am. J. Psychiatry
, vol.156
, pp. 286
-
-
Kapur, S.1
Zipursky, R.B.2
Remington, G.3
-
20
-
-
0000169717
-
IBZM SPECT measurement of D2 receptor occupancy by haloperidol and risperidone
-
Knable, M.B., Heinz, A., Coppola, R., Gorey, J., and Weinberger, D.R., IBZM SPECT measurement of D2 receptor occupancy by haloperidol and risperidone, Biol. Psychiatry, 39 (Abstr.), 515, 1996.
-
(1996)
Biol. Psychiatry
, vol.39
, pp. 515
-
-
Knable, M.B.1
Heinz, A.2
Coppola, R.3
Gorey, J.4
Weinberger, D.R.5
-
21
-
-
0026458521
-
Regulation of transient dopamine concentration gradients in the microenvironment surrounding nerve terminals in the rat striatum
-
Kawagoe, K.T., Garris, P.A., Wiedemann, D.J., and Wightman, R.M., Regulation of transient dopamine concentration gradients in the microenvironment surrounding nerve terminals in the rat striatum, Neuroscience, 51, 55, 1992.
-
(1992)
Neuroscience
, vol.51
, pp. 55
-
-
Kawagoe, K.T.1
Garris, P.A.2
Wiedemann, D.J.3
Wightman, R.M.4
-
22
-
-
0022414990
-
The functional state of the dopamine receptor in the anterior pituitary is in the high-affinity form
-
George, S.R., Watanabe, M., Di Paolo, T., Falardeau, P., Labrie, F., and Seeman, P., The functional state of the dopamine receptor in the anterior pituitary is in the high-affinity form, Endocrinology, 117, 690, 1985.
-
(1985)
Endocrinology
, vol.117
, pp. 690
-
-
George, S.R.1
Watanabe, M.2
Di Paolo, T.3
Falardeau, P.4
Labrie, F.5
Seeman, P.6
-
23
-
-
0026503249
-
PET analysis indicates atypical central dopamine receptor occupancy in clozapine-treated patients
-
Farde, L. and Nordström, A.-L., PET analysis indicates atypical central dopamine receptor occupancy in clozapine-treated patients, Br. J. Psychiatry, 160 (Suppl. 17), 30, 1992.
-
(1992)
Br. J. Psychiatry
, vol.160
, pp. 30
-
-
Farde, L.1
Nordström, A.-L.2
-
24
-
-
0008785952
-
Dopamine-2 receptor imaging in psychotic patients treated with quetiapine, clozapine, risperidone and haloperidol
-
Tauscher, J., Küfferle, B., Barnas, C., Asenbaum, S., Brücke, T., and Kasper, S., Dopamine-2 receptor imaging in psychotic patients treated with quetiapine, clozapine, risperidone and haloperidol, Biol. Psychiatry, 42, 15S, 1997.
-
(1997)
Biol. Psychiatry
, vol.42
, pp. 15
-
-
Tauscher, J.1
Küfferle, B.2
Barnas, C.3
Asenbaum, S.4
Brücke, T.5
Kasper, S.6
-
25
-
-
0030781165
-
IBZM SPECT imaging of striatal dopamine-2 receptors in psychotic patients treated with the novel antipsychotic substance quetiapine in comparison to clozapine and haloperidol
-
Küfferle, B., Tauscher, J., Asenbaum, S., Vesely, C., Podreka, I., Brücke, T., and Kasper, S., IBZM SPECT imaging of striatal dopamine-2 receptors in psychotic patients treated with the novel antipsychotic substance quetiapine in comparison to clozapine and haloperidol, Psychopharmacology, 133, 323, 1997.
-
(1997)
Psychopharmacology
, vol.133
, pp. 323
-
-
Küfferle, B.1
Tauscher, J.2
Asenbaum, S.3
Vesely, C.4
Podreka, I.5
Brücke, T.6
Kasper, S.7
-
26
-
-
0027520871
-
Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients
-
Nordström, A.-L., Farde, L., Wiesel, F.-A., Forslund, K., Pauli, S., Halldin, C., and Uppfeldt, G., Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: a double-blind PET study of schizophrenic patients, Biol. Psychiatry, 33, 227, 1993.
-
(1993)
Biol. Psychiatry
, vol.33
, pp. 227
-
-
Nordström, A.-L.1
Farde, L.2
Wiesel, F.-A.3
Forslund, K.4
Pauli, S.5
Halldin, C.6
Uppfeldt, G.7
-
27
-
-
0008785953
-
2 receptor occupancy of ziprasidone in healthy volunteers
-
2 receptor occupancy of ziprasidone in healthy volunteers, Am. Coll. Neuropsychopharmacol. Abstr., 35, 269, 1996.
-
(1996)
Am. Coll. Neuropsychopharmacol. Abstr.
, vol.35
, pp. 269
-
-
Miceli, J.J.1
Gunn, K.P.2
Rubin, R.H.3
Frackowiak, R.S.J.4
Williams, S.A.5
Fischman, A.6
-
28
-
-
0029991893
-
2 receptors by the neuroleptic ziprasidone (CP-88,059-01) determined by positron emission tomography
-
2 receptors by the neuroleptic ziprasidone (CP-88,059-01) determined by positron emission tomography, Psychopharmacology, 124, 141, 1996.
-
(1996)
Psychopharmacology
, vol.124
, pp. 141
-
-
Bench, C.J.1
Lammertsma, A.A.2
Grasby, P.M.3
Dolan, R.J.4
Warrington, S.J.5
Boyce, M.6
Gunn, K.P.7
Brannick, L.Y.8
Frackowiak, R.S.J.9
-
29
-
-
0008766652
-
Sertindole and dopamine D2 receptor occupancy
-
Kasper, S., Tauscher, J., Küfferle, B., Asenbaum, S., Barnas, C., Hesselmann, B., Podreka, I., and Brücke, T., Sertindole and dopamine D2 receptor occupancy, Biol. Psychiatry, 42, 161S, 1997.
-
(1997)
Biol. Psychiatry
, vol.42
, pp. 161
-
-
Kasper, S.1
Tauscher, J.2
Küfferle, B.3
Asenbaum, S.4
Barnas, C.5
Hesselmann, B.6
Podreka, I.7
Brücke, T.8
-
30
-
-
0031596816
-
2 receptor occupancy in comparison to risperidone, clozapine and haloperidol
-
2 receptor occupancy in comparison to risperidone, clozapine and haloperidol, Psychopharmacology, 136, 367, 1998.
-
(1998)
Psychopharmacology
, vol.136
, pp. 367
-
-
Kasper, S.1
Tauscher, J.2
Küfferle, B.3
Barnas, C.4
Hesselmann, B.5
Asenbaum, S.6
Podreka, I.7
Brücke, T.8
-
31
-
-
0030781693
-
2 receptors: Implications for the therapeutics of schizophrenia
-
2 receptors: implications for the therapeutics of schizophrenia, Am. J. Psychiatry, 154, 1525, 1997.
-
(1997)
Am. J. Psychiatry
, vol.154
, pp. 1525
-
-
Kapur, S.1
Zipursky, R.2
Remington, G.3
Jones, C.4
McKay, G.5
Houle, S.6
-
32
-
-
0028985379
-
123I-IBZM single photon emission tomography (SPET) study
-
123I-IBZM single photon emission tomography (SPET) study, Psychopharmacology, 117, 55, 1995.
-
(1995)
Psychopharmacology
, vol.117
, pp. 55
-
-
Busatto, G.F.1
Pilowsky, L.S.2
Costa, D.C.3
Ell, P.J.4
Verhoeff, N.P.L.G.5
Kerwin, R.W.6
-
33
-
-
0029664735
-
2 dopamine receptors in 56 schizophrenic patients taking various neuroleptics
-
2 dopamine receptors in 56 schizophrenic patients taking various neuroleptics, Am. J. Psychiatry, 153, 183, 1996.
-
(1996)
Am. J. Psychiatry
, vol.153
, pp. 183
-
-
Klemm, E.1
Grünwald, F.2
Kasper, S.3
Menzel, C.4
Broich, K.5
Danos, P.6
Reichmann, K.7
Krappel, C.8
Rieker, O.9
Briele, B.10
Hotze, A.L.11
Möller, H.-J.12
Biersack, H.-J.13
-
34
-
-
0028093301
-
D2-dopamine receptor occupancy differs between patients with and without extrapyramidal side effects
-
Scherer, J., Tatsch, K., Schwarz, J., Oertel, W.H., Konjarczyk, M., and Albus, M., D2-dopamine receptor occupancy differs between patients with and without extrapyramidal side effects, Acta Psychiatr. Scand., 90, 266, 1994.
-
(1994)
Acta Psychiatr. Scand.
, vol.90
, pp. 266
-
-
Scherer, J.1
Tatsch, K.2
Schwarz, J.3
Oertel, W.H.4
Konjarczyk, M.5
Albus, M.6
-
35
-
-
0029658332
-
123I IBZM single photon emission tomography (SPET) study
-
123I IBZM single photon emission tomography (SPET) study, Psychopharmacology, 124, 148, 1996.
-
(1996)
Psychopharmacology
, vol.124
, pp. 148
-
-
Pilowsky, L.S.1
Busatto, G.F.2
Taylor, M.3
Costa, D.C.4
Sharma, T.5
Sigmundsson, T.6
Ell, P.J.7
Nohria, V.8
Kerwin, R.W.9
-
36
-
-
0000217228
-
D2 receptor occupancy in risperidone and clozapine-treated schizophrenics
-
Su, T.-P., Breier, A., Coppola, R., Hadd, K., Elman, I., Adler, C., Malhotra, A.K., Watsky, E., Gorey, J., Weinberger, D., and Pickar, D., D2 receptor occupancy in risperidone and clozapine-treated schizophrenics, Biol. Psychiatry, 39, 512, 1996.
-
(1996)
Biol. Psychiatry
, vol.39
, pp. 512
-
-
Su, T.-P.1
Breier, A.2
Coppola, R.3
Hadd, K.4
Elman, I.5
Adler, C.6
Malhotra, A.K.7
Watsky, E.8
Gorey, J.9
Weinberger, D.10
Pickar, D.11
-
37
-
-
0008802994
-
D2 receptor occupancy during risperidone and clozapine treatment in chronic schizophrenia: Relationship to blood level, efficacy and EPS
-
Su, T.-P., Breier, A., Coppola, R., Hadd, K., Elman, I., Alder, C., Malhotra, A.K., Watsky, E., Gorey, J., Hough, C.J., Weinberger, D., and Pickar, D., D2 receptor occupancy during risperidone and clozapine treatment in chronic schizophrenia: relationship to blood level, efficacy and EPS, Soc. Neurosci. Abstr., 22, 265, 1996.
-
(1996)
Soc. Neurosci. Abstr.
, vol.22
, pp. 265
-
-
Su, T.-P.1
Breier, A.2
Coppola, R.3
Hadd, K.4
Elman, I.5
Alder, C.6
Malhotra, A.K.7
Watsky, E.8
Gorey, J.9
Hough, C.J.10
Weinberger, D.11
Pickar, D.12
-
38
-
-
0031284854
-
2 dopamine receptor occupancy: A crossover comparison of risperidone with clozapine therapy in schizophrenic patients
-
2 dopamine receptor occupancy: a crossover comparison of risperidone with clozapine therapy in schizophrenic patients, Arch. Gen. Psychiatry, 54, 972, 1997.
-
(1997)
Arch. Gen. Psychiatry
, vol.54
, pp. 972
-
-
Su, T.-P.1
Malhotra, A.K.2
Hadd, K.3
Breier, A.4
Pickar, D.5
-
39
-
-
0008784677
-
D2 and 5HT2A receptor binding of different doses of quetiapine in schizophrenics: A PET study
-
Gefvert, O., Lundberg, T., Wieselgren, I.-M., Hagström, P., Bergström, M., Långström, B., Wiesel, F.-A., Yates, R., and Lindström, L.H., D2 and 5HT2A receptor binding of different doses of quetiapine in schizophrenics: a PET study, Am. Coll. Neuropsychopharmacol. Abstr., 36, 168, 1997.
-
(1997)
Am. Coll. Neuropsychopharmacol. Abstr.
, vol.36
, pp. 168
-
-
Gefvert, O.1
Lundberg, T.2
Wieselgren, I.-M.3
Hagström, P.4
Bergström, M.5
Långström, B.6
Wiesel, F.-A.7
Yates, R.8
Lindström, L.H.9
-
40
-
-
0025941654
-
2 dopamine receptor binding differences of clozapine and haloperidol
-
2 dopamine receptor binding differences of clozapine and haloperidol, J. Neural Transm., 86, 163, 1991.
-
(1991)
J. Neural Transm.
, vol.86
, pp. 163
-
-
Karbe, H.1
Wienhard, K.2
Hamacher, K.3
Huber, M.4
Herholz, K.5
Coenen, H.H.6
Stöcklin, G.7
Lövenich, A.8
Heiss, W.D.9
-
41
-
-
0001453234
-
18FESP, in New Generation of Antipsychotic Drugs: Novel Mechanisms of Action
-
Brunello, N., Mendlewicz, J., and Racagni, G., Eds., S. Karger, Basel
-
18FESP, in New Generation of Antipsychotic Drugs: Novel Mechanisms of Action, Vol. 4, Brunello, N., Mendlewicz, J., and Racagni, G., Eds., International Academy of Biomedical Drug Research, S. Karger, Basel, 1993, 130.
-
(1993)
International Academy of Biomedical Drug Research
, vol.4
, pp. 130
-
-
Louwerens, J.W.1
Buddingh, J.A.2
Zijlstra, S.3
Pruim, J.4
Korf, J.5
Paans, A.M.J.6
Vaalburg, W.7
Slooff, C.J.8
-
42
-
-
2042448833
-
Dopamine2-and serotonin2-receptor-antagonism by antipsychotics in man
-
Louwerens, J.W., Slooff, C.J., Korf, J., Coppens, H.J., and Paans, A.M.J., Dopamine2-and serotonin2-receptor-antagonism by antipsychotics in man, Schizophr. Res., 18 (Abstr.), 141, 1996.
-
(1996)
Schizophr. Res.
, vol.18
, pp. 141
-
-
Louwerens, J.W.1
Slooff, C.J.2
Korf, J.3
Coppens, H.J.4
Paans, A.M.J.5
-
43
-
-
2042440167
-
11C NMSP receptor occupancy by clozapine and haloperidol in schizophrenic subjects
-
11C NMSP receptor occupancy by clozapine and haloperidol in schizophrenic subjects, Schizophr. Res., 15 (Abstr.), 80, 1995.
-
(1995)
Schizophr. Res.
, vol.15
, pp. 80
-
-
Conley, R.1
Medoff, D.2
Wong, D.3
Tamminga, C.4
-
44
-
-
0008802558
-
11C NMSP receptor occupancy by clozapine and haloperidol in schizophrenic subjects
-
11C NMSP receptor occupancy by clozapine and haloperidol in schizophrenic subjects, Biol. Psychiatry, 39 (Abstr.), 513, 1996.
-
(1996)
Biol. Psychiatry
, vol.39
, pp. 513
-
-
Conley, R.1
Zhao, M.2
Wong, D.3
Tamminga, C.4
-
45
-
-
0029658718
-
2 dopamine receptor occupancy in clozapine-treated patients
-
2 dopamine receptor occupancy in clozapine-treated patients, Am. J. Psychiatry, 153, 1571, 1996.
-
(1996)
Am. J. Psychiatry
, vol.153
, pp. 1571
-
-
Pickar, D.1
Su, T.-P.2
Weinberger, D.R.3
Coppola, R.4
Malhotra, A.K.5
Knable, M.B.6
Lee, K.S.7
Gorey, J.8
Bartko, J.J.9
Breier, A.10
Hsiao, J.11
-
46
-
-
0028785179
-
New insights into the biology of schizophrenia through the mechanism of action of clozapine
-
Brunello, N., Masotto, C., Steardo, L., Markstein, R., and Racagni, G., New insights into the biology of schizophrenia through the mechanism of action of clozapine, Neuropsychopharmacology, 13, 177, 1995.
-
(1995)
Neuropsychopharmacology
, vol.13
, pp. 177
-
-
Brunello, N.1
Masotto, C.2
Steardo, L.3
Markstein, R.4
Racagni, G.5
-
47
-
-
0343907220
-
Clozapine occupies high levels of dopamine D2 receptors
-
Seeman, P. and Kapur, S., Clozapine occupies high levels of dopamine D2 receptors, Life Sci., 60, 207, 1997.
-
(1997)
Life Sci.
, vol.60
, pp. 207
-
-
Seeman, P.1
Kapur, S.2
-
48
-
-
0032973806
-
2 receptors: An explanation for low receptor occupancy and early clinical relapse upon drug withdrawal of clozapine or quetiapine
-
2 receptors: an explanation for low receptor occupancy and early clinical relapse upon drug withdrawal of clozapine or quetiapine, Am. J. Psychiatry, 156, 876, 1999.
-
(1999)
Am. J. Psychiatry
, vol.156
, pp. 876
-
-
Seeman, P.1
Tallerico, T.2
-
49
-
-
0030859144
-
Limbic selectivity of clozapine
-
Pilowsky, L.S., Mulligan, R.S., Acton, P.D., Ell, P.J., Costa, D.C., and Kerwin, R.W., Limbic selectivity of clozapine, Lancet, 350, 490, 1997.
-
(1997)
Lancet
, vol.350
, pp. 490
-
-
Pilowsky, L.S.1
Mulligan, R.S.2
Acton, P.D.3
Ell, P.J.4
Costa, D.C.5
Kerwin, R.W.6
-
50
-
-
0024595594
-
Endogenous dopamine lowers the dopamine D2 receptor density as measured by [3H]raclopride: Implications for positron emission tomography of the human brain
-
Seeman, P., Guan, H.-C., and Niznik, H.B., Endogenous dopamine lowers the dopamine D2 receptor density as measured by [3H]raclopride: implications for positron emission tomography of the human brain, Synapse, 3, 96, 1989.
-
(1989)
Synapse
, vol.3
, pp. 96
-
-
Seeman, P.1
Guan, H.-C.2
Niznik, H.B.3
-
51
-
-
6844245465
-
SPECT measurement of human striatal synaptic dopamine concentration in the resting state
-
Laruelle, M., De Souza, C., Baldwin, R.M., Abi-Dargham, A., Bowers, M., Seibyl, J.P., Charney, D.S., and Innis, R.B., SPECT measurement of human striatal synaptic dopamine concentration in the resting state, Soc. Neurosci. Abstr., 22 (Abstr.), 266, 1996.
-
(1996)
Soc. Neurosci. Abstr.
, vol.22
, pp. 266
-
-
Laruelle, M.1
De Souza, C.2
Baldwin, R.M.3
Abi-Dargham, A.4
Bowers, M.5
Seibyl, J.P.6
Charney, D.S.7
Innis, R.B.8
-
52
-
-
0029787944
-
Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug free schizophrenic subjects
-
Laruelle, M., Abi-Dargham, A., van Dyck, C.H., Gil, R., De Souza, C.D., Erdos, J., McCance, E., Rosenblatt, W., Fingado, C., Zoghbi, S.S., Baldwin, R.M., Seibyl, J.P., Krystal, J.H., Charney, D.S., and Innis, R.B., Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug free schizophrenic subjects, Proc. Natl. Acad. Sci. U.S.A., 93, 9235, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 9235
-
-
Laruelle, M.1
Abi-Dargham, A.2
van Dyck, C.H.3
Gil, R.4
De Souza, C.D.5
Erdos, J.6
McCance, E.7
Rosenblatt, W.8
Fingado, C.9
Zoghbi, S.S.10
Baldwin, R.M.11
Seibyl, J.P.12
Krystal, J.H.13
Charney, D.S.14
Innis, R.B.15
-
53
-
-
0030608782
-
2 receptor occupancy by endogenous dopamine in humans
-
2 receptor occupancy by endogenous dopamine in humans, Neuropsychopharmacology, 17, 162, 1997.
-
(1997)
Neuropsychopharmacology
, vol.17
, pp. 162
-
-
Laruelle, M.1
D’Souza, C.D.2
Baldwin, R.M.3
Abi-Dargham, A.4
Kanes, S.J.5
Fingado, C.L.6
Seibyl, J.P.7
Zoghbi, S.S.8
Bowers, M.B.9
Jatlow, P.10
Charney, D.S.11
Innis, R.B.12
-
54
-
-
0030991805
-
Clozapine inhibits catalepsy induced by olanzapine and loxapine, but prolongs catalepsy induced by SCH 23390 in rats
-
Kalkman, H.O., Neumann, V., and Tricklebank, M.D., Clozapine inhibits catalepsy induced by olanzapine and loxapine, but prolongs catalepsy induced by SCH 23390 in rats, Naunyn-Schmiedeberg’s Arch. Pharmakol., 355, 361, 1997.
-
(1997)
Naunyn-Schmiedeberg’s Arch. Pharmakol.
, vol.355
, pp. 361
-
-
Kalkman, H.O.1
Neumann, V.2
Tricklebank, M.D.3
-
55
-
-
7144244342
-
2 receptor occupancy induced by risperidone in schizophrenic patients
-
2 receptor occupancy induced by risperidone in schizophrenic patients, Am. Coll. Neuropsychopharmacol., 35 (Abstr.), 184, 1996.
-
(1996)
Am. Coll. Neuropsychopharmacol.
, vol.35
, pp. 184
-
-
Nyberg, S.1
Eriksson, B.2
Oxenstierna, G.3
Halldin, C.4
Farde, L.5
-
56
-
-
0029984110
-
2 receptor occupancy studies and clinical response
-
2 receptor occupancy studies and clinical response, Br. J. Psychiatry, 168, 40, 1996.
-
(1996)
Br. J. Psychiatry
, vol.168
, pp. 40
-
-
Nyberg, S.1
Nakashima, Y.2
Nordström, A.-L.3
Halldin, C.4
Farde, L.5
-
57
-
-
0030294642
-
2 receptor blocking agent, ritanserin, in the rat
-
2 receptor blocking agent, ritanserin, in the rat, Eur. Neuropsychopharmacol., 6, 305, 1996.
-
(1996)
Eur. Neuropsychopharmacol.
, vol.6
, pp. 305
-
-
Wadenberg, M.-L.1
Salmi, P.2
Jimenez, P.3
Svensson, T.4
Ahlenius, S.5
-
58
-
-
0030906167
-
2A/C antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release
-
2A/C antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release, Psychopharmacology, 131, 57, 1997.
-
(1997)
Psychopharmacology
, vol.131
, pp. 57
-
-
Lucas, G.1
Bonhomme, N.2
De Deurwaerdère, P.3
Le Moal, M.4
Spampinato, U.5
-
59
-
-
0344846832
-
Dopamine and serotonin receptor occupancy examined by PET in antipsychotic drug treated patients
-
Farde, L., Nyberg, S., Nordström, A.-L., Halldin, C., and Sedvall, G., Dopamine and serotonin receptor occupancy examined by PET in antipsychotic drug treated patients, Am. Coll. Neuropsychopharmacol., 32 (Abstr.), 38, 1993.
-
(1993)
Am. Coll. Neuropsychopharmacol.
, vol.32
, pp. 38
-
-
Farde, L.1
Nyberg, S.2
Nordström, A.-L.3
Halldin, C.4
Sedvall, G.5
-
60
-
-
0023812652
-
Clozapine for the treatment-resistant schizophrenic: A double-blind comparison with chlorpromazine
-
Kane, J., Honigfeld, G., Singer, J., Meltzer, H.Y., and the Clozaril Collaborative Study Group, Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine, Arch. Gen. Psychiatry, 45, 789, 1988.
-
(1988)
Arch. Gen. Psychiatry
, vol.45
, pp. 789
-
-
Kane, J.1
Honigfeld, G.2
Singer, J.3
Meltzer, H.Y.4
-
61
-
-
0027431505
-
Case report 2: Remoxipride in resistant schizophrenia
-
Scurlock, H.J. and Robinson, P.H., Case report 2: remoxipride in resistant schizophrenia, J. Drug Dev., 6, 71, 1993.
-
(1993)
J. Drug Dev.
, vol.6
, pp. 71
-
-
Scurlock, H.J.1
Robinson, P.H.2
-
62
-
-
0029053001
-
Atypical antipsychotic drugs in the treatment of manic syndromes in patients with HIV-1 infection
-
Scurlock, H.J., Singh, A.N., and Catalan, J., Atypical antipsychotic drugs in the treatment of manic syndromes in patients with HIV-1 infection, J. Psychopharmacol., 9, 151, 1995.
-
(1995)
J. Psychopharmacol.
, vol.9
, pp. 151
-
-
Scurlock, H.J.1
Singh, A.N.2
Catalan, J.3
-
63
-
-
0027463029
-
A long-term study of remoxipride in chronic schizophrenic patients
-
Vartianen, H., Leinonen, E., Putkonen, A., Lang, S., Hagert, U., and Tolvanen, U., A long-term study of remoxipride in chronic schizophrenic patients, Acta Psychiatr. Scand., 87, 114, 1993.
-
(1993)
Acta Psychiatr. Scand.
, vol.87
, pp. 114
-
-
Vartianen, H.1
Leinonen, E.2
Putkonen, A.3
Lang, S.4
Hagert, U.5
Tolvanen, U.6
-
64
-
-
0029119464
-
Clinical implications of clozapine discontinuation: Report of an NIMH workshop
-
Shore, D., Matthews, S., Cott, J., and Lieberman, J.A., Clinical implications of clozapine discontinuation: report of an NIMH workshop, Schizophr. Bull., 21, 333, 1995.
-
(1995)
Schizophr. Bull.
, vol.21
, pp. 333
-
-
Shore, D.1
Matthews, S.2
Cott, J.3
Lieberman, J.A.4
-
65
-
-
0029916129
-
Relapse following clozapine withdrawal: Effect of neuroleptic drugs and cyproheptadine
-
Meltzer, H.Y., Lee, M.A., Ranjan, R., Mason, E.A., and Cola, P.A., Relapse following clozapine withdrawal: effect of neuroleptic drugs and cyproheptadine, Psychopharmacology, 124, 176, 1996.
-
(1996)
Psychopharmacology
, vol.124
, pp. 176
-
-
Meltzer, H.Y.1
Lee, M.A.2
Ranjan, R.3
Mason, E.A.4
Cola, P.A.5
-
66
-
-
1542660867
-
123I-IBZM SPECT following clozapine dose reduction
-
123I-IBZM SPECT following clozapine dose reduction, Schizophr. Res., 15 (Abstr.), 96, 1995.
-
(1995)
Schizophr. Res.
, vol.15
, pp. 96
-
-
Pickar, D.1
Su, T.-P.2
Coppola, R.3
Lee, C.S.4
Hsiao, J.K.5
Breier, A.6
Weinberger, D.R.7
-
67
-
-
0024426716
-
Striatal dopamine receptor occupancy during and following withdrawal from neuroleptic treatment: Correlative evaluation by positron emission tomography and plasma prolactin levels
-
Baron, J.C., Martinot, J.L., Cambon, H., Boulenger, J.P., Poirier, M.F., Caillard, V., Blin, J., Huret, J.D., Loc’h, C., and Maziere, B., Striatal dopamine receptor occupancy during and following withdrawal from neuroleptic treatment: correlative evaluation by positron emission tomography and plasma prolactin levels, Psychopharmacology, 99, 463, 1989.
-
(1989)
Psychopharmacology
, vol.99
, pp. 463
-
-
Baron, J.C.1
Martinot, J.L.2
Cambon, H.3
Boulenger, J.P.4
Poirier, M.F.5
Caillard, V.6
Blin, J.7
Huret, J.D.8
Loc’h, C.9
Maziere, B.10
-
68
-
-
0024418579
-
Clozapine in the treatment of psychosis in Parkinson’s disease
-
Friedman, J.H. and Lannon, M.C., Clozapine in the treatment of psychosis in Parkinson’s disease, Neurology, 39, 1219, 1989.
-
(1989)
Neurology
, vol.39
, pp. 1219
-
-
Friedman, J.H.1
Lannon, M.C.2
-
69
-
-
0025113382
-
Clozapine for psychosis in Parkinson’s disease
-
Pfeiffer, R.F., Kang, J., Graber, B., Hofman, R., and Wilson, J., Clozapine for psychosis in Parkinson’s disease, Movement Disord., 5, 239, 1990.
-
(1990)
Movement Disord.
, vol.5
, pp. 239
-
-
Pfeiffer, R.F.1
Kang, J.2
Graber, B.3
Hofman, R.4
Wilson, J.5
-
70
-
-
0026000655
-
Clozapine is beneficial for psychosis in Parkinson’s disease
-
Kahn, N., Freeman, A., Juncos, J.L., Manning, D., and Watts, R.L., Clozapine is beneficial for psychosis in Parkinson’s disease, Neurology, 41, 1699, 1991.
-
(1991)
Neurology
, vol.41
, pp. 1699
-
-
Kahn, N.1
Freeman, A.2
Juncos, J.L.3
Manning, D.4
Watts, R.L.5
-
71
-
-
0026511671
-
Clozapine prevents recurrence of psychosis in Parkinson’s disease
-
Factor, S.A. and Brown, D., Clozapine prevents recurrence of psychosis in Parkinson’s disease, Movement Disord., 7, 125, 1992.
-
(1992)
Movement Disord.
, vol.7
, pp. 125
-
-
Factor, S.A.1
Brown, D.2
-
72
-
-
0029064499
-
Low-dose clozapine in the treatment of levodopa-induced mental disturbances in Parkinson’s disease
-
Rabey, J.M., Treves, T.A., Neufeld, M.Y., Orlov, E., and Korczyn, A.D., Low-dose clozapine in the treatment of levodopa-induced mental disturbances in Parkinson’s disease, Neurology, 45, 432, 1995.
-
(1995)
Neurology
, vol.45
, pp. 432
-
-
Rabey, J.M.1
Treves, T.A.2
Neufeld, M.Y.3
Orlov, E.4
Korczyn, A.D.5
-
73
-
-
0029843329
-
Remoxipride in the treatment of levodopa-induced psychosis
-
Sandor, P., Lang, A.E., Singal, S., and Angus, C., Remoxipride in the treatment of levodopa-induced psychosis, J. Clin. Psychopharmacol., 16, 395, 1996.
-
(1996)
J. Clin. Psychopharmacol.
, vol.16
, pp. 395
-
-
Sandor, P.1
Lang, A.E.2
Singal, S.3
Angus, C.4
-
74
-
-
0028920801
-
Plasma clozapine levels and the treatment of L-DOPA-induced psychosis in Parkinson’s disease. A high potency effect of clozapine
-
Meltzer, H.Y., Kennedy, J., Dai, J., Parsa, M., and Riley, D., Plasma clozapine levels and the treatment of L-DOPA-induced psychosis in Parkinson’s disease. A high potency effect of clozapine, Neuropsychopharmacology, 12, 39, 1995.
-
(1995)
Neuropsychopharmacology
, vol.12
, pp. 39
-
-
Meltzer, H.Y.1
Kennedy, J.2
Dai, J.3
Parsa, M.4
Riley, D.5
-
75
-
-
0027485692
-
Dopamine D4 receptors elevated in schizophrenia
-
Seeman, P., Guan, H.-C., and Van Tol, H.H.M., Dopamine D4 receptors elevated in schizophrenia, Nature, 365, 441, 1993.
-
(1993)
Nature
, vol.365
, pp. 441
-
-
Seeman, P.1
Guan, H.-C.2
Van Tol, H.H.M.3
-
76
-
-
0023027609
-
2 dopamine receptors in drug-naive schizophrenics
-
2 dopamine receptors in drug-naive schizophrenics, Science, 234, 1558, 1986.
-
(1986)
Science
, vol.234
, pp. 1558
-
-
Wong, D.F.1
Wagner, H.N.2
Tune, L.E.3
Dannals, R.F.4
Pearlson, G.D.5
Links, J.M.6
Tamminga, C.A.7
Broussolle, E.P.8
Ravert, H.T.9
Wilson, A.A.10
Toung, J.K.T.11
Malat, J.12
Williams, J.A.13
O’Tuama, L.A.14
Snyder, S.H.15
Kuhar, M.J.16
Gjedde, A.17
-
77
-
-
0028983794
-
11C]N-methylspiperone
-
11C]N-methylspiperone, Psychiatr. Res. Neuroimaging, 61, 67, 1995.
-
(1995)
Psychiatr. Res. Neuroimaging
, vol.61
, pp. 67
-
-
Nordström, A.-L.1
Farde, L.2
Eriksson, L.3
Halldin, C.4
-
78
-
-
0025194556
-
D2 dopamine receptors in neuroleptic-naive schizophrenic patients
-
Farde, L., Wiesel, F.-A., Stone-Elander, S., Halldin, C., Nordström, A.-A., Hall, H., and Sedvall, G., D2 dopamine receptors in neuroleptic-naive schizophrenic patients, Arch. Gen. Psychiatry, 47, 213, 1990.
-
(1990)
Arch. Gen. Psychiatry
, vol.47
, pp. 213
-
-
Farde, L.1
Wiesel, F.-A.2
Stone-Elander, S.3
Halldin, C.4
Nordström, A.-A.5
Hall, H.6
Sedvall, G.7
-
79
-
-
0032422474
-
Dopamine D2 receptor dimers in human and rat brain
-
Zawarynski, P., Tallerico, T., Seeman, P., Lee, S.P., O’Dowd, B.F., and George, S.R., Dopamine D2 receptor dimers in human and rat brain, FEBS Letts., 441, 383, 1998.
-
(1998)
FEBS Letts.
, vol.441
, pp. 383
-
-
Zawarynski, P.1
Tallerico, T.2
Seeman, P.3
Lee, S.P.4
O’Dowd, B.F.5
George, S.R.6
-
80
-
-
0028104820
-
Phosphorylation and palmitoylation of the human D2L dopamine receptor in Sf9 cells
-
Ng, G.Y.K., O’Dowd, B.F., Caron, M., Dennis, M., Brann, M.R., and George, S.R., Phosphorylation and palmitoylation of the human D2L dopamine receptor in Sf9 cells, J. Neurochem., 63, 1589, 1994.
-
(1994)
J. Neurochem.
, vol.63
, pp. 1589
-
-
Ng, G.Y.K.1
O’Dowd, B.F.2
Caron, M.3
Dennis, M.4
Brann, M.R.5
George, S.R.6
-
81
-
-
0030567986
-
Dopamine D2 receptor dimers and receptor-blocking peptides
-
Ng, G.Y.K., O’Dowd, B.F., Lee, S.P., Chung, H.T., Brann, M.R., Seeman, P., and George, S.R., Dopamine D2 receptor dimers and receptor-blocking peptides, Biochem. Biophys. Res. Commun., 227, 200, 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.227
, pp. 200
-
-
Ng, G.Y.K.1
O’Dowd, B.F.2
Lee, S.P.3
Chung, H.T.4
Brann, M.R.5
Seeman, P.6
George, S.R.7
-
82
-
-
85047676970
-
L receptor to desensitization accompanies the up-regulation of receptors on to the surface of Sf9 cells
-
L receptor to desensitization accompanies the up-regulation of receptors on to the surface of Sf9 cells, Endocrinology, 138, 4199, 1997.
-
(1997)
Endocrinology
, vol.138
, pp. 4199
-
-
Ng, G.Y.K.1
Varghese, G.2
Chung, H.T.3
Trogadis, J.4
Seeman, P.5
O’Dowd, B.F.6
George, S.R.7
-
83
-
-
0009945122
-
Imaging intrasynaptic postsynaptic and presynaptic dopamine function in psychosis
-
Wong, D.F., Gjedde, A., Reith, J., Grunder, G., Szymanski, S., Yokoi, F., Hong, C., Nestadt, G., Neufeld, K., Pearlson, G., Tune, L., and Angrist, B., Imaging intrasynaptic postsynaptic and presynaptic dopamine function in psychosis, Soc. Neurosci. Abstr., 23, 1405, 1997.
-
(1997)
Soc. Neurosci. Abstr.
, vol.23
, pp. 1405
-
-
Wong, D.F.1
Gjedde, A.2
Reith, J.3
Grunder, G.4
Szymanski, S.5
Yokoi, F.6
Hong, C.7
Nestadt, G.8
Neufeld, K.9
Pearlson, G.10
Tune, L.11
Angrist, B.12
-
84
-
-
0025944212
-
3H]spiperone binding in vivo in rat brain
-
3H]spiperone binding in vivo in rat brain, J. Receptor Res., 11, 163, 1991.
-
(1991)
J. Receptor Res.
, vol.11
, pp. 163
-
-
Bischoff, S.1
Krauss, J.2
Grunenwald, C.3
Gunst, F.4
Heinrich, M.5
Schaub, M.6
Stöcklin, K.7
Vassout, A.8
Waldmeier, P.9
Maître, L.10
-
85
-
-
10644266719
-
Baseline dopamine synaptic concentration is increased in schizophrenia and related to treatment response
-
Abi-Dargham, A., Kegeles, L., Zea-Ponce, Y., Printz, D., Rodenhiser, J., Weiss, R., Mann, J., Gorman, J., Van Heertum, R., and Laruelle, M., Baseline dopamine synaptic concentration is increased in schizophrenia and related to treatment response, Soc. Neurosci. Abstr., 24, 525, 1998.
-
(1998)
Soc. Neurosci. Abstr.
, vol.24
, pp. 525
-
-
Abi-Dargham, A.1
Kegeles, L.2
Zea-Ponce, Y.3
Printz, D.4
Rodenhiser, J.5
Weiss, R.6
Mann, J.7
Gorman, J.8
Van Heertum, R.9
Laruelle, M.10
-
86
-
-
12644293806
-
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method
-
Breier, A., Su, T.-P., Saunders, R., Carson, R.E., Kolachana, B.S., De Bartolomeis, A., Weinberger, D.R., Weisenfeld, N., Malhotra, A.K., Eckelman, W.C., and Pickar, D., Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method, Proc. Natl. Acad. Sci. U.S.A., 94, 2569, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 2569
-
-
Breier, A.1
Su, T.-P.2
Saunders, R.3
Carson, R.E.4
Kolachana, B.S.5
De Bartolomeis, A.6
Weinberger, D.R.7
Weisenfeld, N.8
Malhotra, A.K.9
Eckelman, W.C.10
Pickar, D.11
-
87
-
-
0031799667
-
Increased striatal dopamine transmission in schizophrenia: Confirmation in a second cohort
-
Abi-Dargham, A., Gil, R., Krystal, J., Baldwin, R.M., Seibyl, J.P., Bowers, M., van Dyck, C.H., Charney, D.S., Innis, R.B., and Laruelle, M., Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort, Am. J. Psychiatry, 155, 761, 1998.
-
(1998)
Am. J. Psychiatry
, vol.155
, pp. 761
-
-
Abi-Dargham, A.1
Gil, R.2
Krystal, J.3
Baldwin, R.M.4
Seibyl, J.P.5
Bowers, M.6
van Dyck, C.H.7
Charney, D.S.8
Innis, R.B.9
Laruelle, M.10
-
88
-
-
0024854498
-
Link between D1 and D2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain
-
Seeman, P., Niznik, H.B., Guan, H.-C., Booth, G., and Ulpian, C., Link between D1 and D2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain, Proc. Natl. Acad. Sci. U.S.A., 86, 10156, 1989.
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 10156
-
-
Seeman, P.1
Niznik, H.B.2
Guan, H.-C.3
Booth, G.4
Ulpian, C.5
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