Theoretical study on receptor-G protein recognition: New insights into the mechanism of the α1b-adrenergic receptor activation

International Journal of Quantum Chemistry

Volumn 73, Issue 2, 1999, Pages 71-83

  Fanelli, Francesca ^a   Menziani, Cristina ^a   Scheer, Alexander ^b   Cotecchia, Susanna ^b   De Benedetti, Pier G ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Adrenergic receptors; Docking; Electrostatic potential; G proteins; Homology modeling; Molecular dynamics

Indexed keywords

EID: 0002047990     PISSN: 00207608     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-461X(1999)73:2<71::AID-QUA3>3.0.CO;2-3     Document Type: Article

References (24)

1. Khorana, H. G. J Biol Chem 1992, 267, 1-4.
2. Coleman, D. E.; Sprang, S. TIBS 1996, 21, 41-44.
3. Bohm, A.; Gaudet, R.; Sigler, O. B. Curr Opinion Biotecnol 1997, 8, 480-487.
4. Wess, J. FASEB J 1997, 11, 346-354.
5. Lichtarge, O.; Bourne, H. R.; Cohen, F. E, Proc Natl Acad Sci USA 1996, 93, 7507-7511.
6. Onrust, R.; Herzmark, P.; Chi, P.; Garcia, P. D.; Lichtarge, O.; Kingsley, C; Bourne, H. R. Science 1997, 275, 381-384.
7. Gilchrist, A.; Mazzoni, M. R.; Dinnen, B.; Dice, A.; Linden, J.; Proctor, W. R.; Lupica, C.; Dunwiddie, T. V.; Hamm, H. E. J Biol Chem 1998, 273, 14912-14919.
8. Unger, V. M.; Hargrave, P. A.; Baldwin, J. M.; Schertler, G. F. Nature 1997, 389, 203-206.
9. Baldwin, J. M.; Schertler, G. F.; Unger, V. M. J Mol Biol 1997, 272, 144-164.
10. Bourne, H. R. Curr Opinion Cell Biol 1997, 9, 134-142; and references therein.
11. Gether, U.; Kobilka, B. J Biol Chem 1998, 273, 17979-17982; and references therein.
12. Scheer, A.; Fanelli, F.; Costa, T.; De Benedetti, P. G.; Cotecchia, S. EMBO J 1996, 15, 3566-3578.
13. Scheer, A.; Fanelli, F.; Costa, T.; De Benedetti, P. G.; Cotecchia, S. Proc Natl Acad Sci (USA) 1997, 94, 808-813.
14. Fanelli, F.; Menziani, C; Scheer, A.; Cotecchia, S.; De Benedetti, P. G. Meth Companion Meth in Enzymol 1998, 14, 302-317.
15. Kim, J. M.; Altenbach, C.; Thurmond, R. L.; Khorana, H. G.; Hubbell, W. L. Proc Natl Acad Sci (USA) 1997, 94, 14273-14278.
16. Wall, M. A.; Coleman, D. E.; Lee, E.; Iniguez-Lluhi, J. A.; Posner, B. A.; Gilman, A. G.; Sprang, S. Cell 1995, 83, 1047,
17. Baldwin, J. M. EMBO J 1993, 12, 1693-1703.
18. Cavalli, A.; Fanelli, F.; Taddei, C; De Benedetti, P. G.; Cotecchia, S. FEBS Lett 1996, 339, 9-13.
19. Ausiello, G.; Cesareni, G.; Helmer-Citterich, M. Proteins 1997, 28, 556-567.
20. Javitch, J. A.; Ballesteros, J. A.; Weinstein, H.; Chen, J. Biochemistry 1998, 37, 998-1006.
21. Herbet, T. E.; Moffett, S.; Morello, J.-P.; Loisel, T. P.; Bichet, D. G.; Barret, C.; Bouvier, M. J Biol Chem 1996, 271, 16384-16392.
22. Bertin, B.; Freissmuth, M.; Jockers, R.; Strosberg, A. D. Proc Natl Acad Sci (USA) 1994, 91, 8827-8831.
23. Mazzoni, M. R.; Hamm, H. E. J Biol Chem 1996, 271, 30034-30040.
24. Cotecchia, S.; Exum, S.; Caron, M. G.; Lefkowitz, R. Proc Natl Acad Sci (USA) 1990, 87, 2896-2900,