Clinical trials of anti-vascular agent group B Streptococcus toxin (CM101)

Angiogenesis

Volumn 1, Issue 1, 1997, Pages 36-37

  Harris, Adrian L ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001951179     PISSN: 09696970     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018353015650     Document Type: Review

References (9)

1. DeVore RF, Hellerqvist CG, Wakefield GB, et al. Phase 1 study of the antineovascularization drug CM101. Clin Cancer Res 1997; 3, 365-372.
2. Wamil BD, Thurman BD, Sundell HW, et al. Soluble E-selectin in cancer patients as a marker of the therapeutic efficiency of CM101, a tumour-inhibiting antineovascularization agent, evaluated in phase 1 clinical trial. J Cancer Res Clin Oncol 1997; 123, 173-179.
3. Eckhardt SG, Burris HA, Eckardt JR, et al. A phase-1 clinical and pharmacokinetic study of the angiogenesis inhibitor, tecogalan sodium. Ann Oncol 1996; 7, 491-496.
4. Borgstrom P, Hillan KJ, Sriramarao P, Ferrara N. Complete inhibition of angiogenesis and growth of microtumours by antivascular endothelial growth-factor neutralizing antibody - novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res 1996; 56, 4032-4039.
5. Volpert OV, Ward WF, Lingen NW, et al. Captopril inhibits angiogenesis and slows the growth of experimental-tumours in rats. J Clin Invest 1996; 98, 671-679.
6. Klauber N, Parangi S, Flynn E, Hamel E, Damato RJ. Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Res 1997; 57, 81-86.
7. Hockel M, Schlenger K, Aral B, Mitze M, Schaffer U, Vaupel P. Association between tumour hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res 1996; 56, 4509-4515.
8. Xu M, Kumar D, Srinivas S, et al. Parenteral gene-therapy with p53 inhibits human breast-tumours in-vivo through a bystander mechanism without evidence of toxicity. Human Gene Therapy 1997; 8, 177-185.
9. Huang X-M, Molema G, King S, Watkins L, Edgington TS, Thorpe PE. Tumor infarction in mice by antibody-directed targeting of tissue factor to tumour vasculature. Science 1997; 275, 547-550.