The enantioselective synthesis of anti-β-hydroxy-α-amino acids via the reaction of lithium enolates of glycine bearing an oxazolidine chiral auxiliary with aldehydes

Synlett

Volumn , Issue 6, 1998, Pages 664-666

  Iwanowicz, Edwin J ^a   Blomgren, Peter ^a   Cheng, Peter T W ^a   Smith, Kennith ^b   Lau, Wan F ^a   Pan, Yolanda Y ^a   Gu, Henry H ^a   Malley, Mary F ^a   Gougoutas, Jack Z ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^b GENERAL ELECTRIC COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001931504     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1736     Document Type: Article

References (36)

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24. Fractional atomic coordinates have been deposited with the Cambridge Crystallographic Datacenter.
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27. Value calculated from Æ G = -RTlnK at 298 K.
28. 3 at 50 °C.
29. 4.
30. 2H (6/1/1) at rt., 24h.
31. 2, MeOH.
32. c) anhydrous HF at 0°C, 15min.
33. d) Dowex-1.
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