Ligand binding: proteinase-protein inhibitor interactions. Current opinion in structural biology 1991, 1:45-52

Current Opinion in Structural Biology

Volumn 1, Issue 1, 1991, Pages 45-52

  Bode, Wolfram ^a   Huber, Robert ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001918129     PISSN: 0959440X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-440X(91)90010-Q     Document Type: Article

References (52)

1. Cysteine Proteinase Inhibitors of the Cystatin Superfamily
2. Introduction to the Protein Inhibitors: X-Ray Crystallography
3. Structure of the Trypsin-Binding Domain of Bowman-Birk Type Protease Inhibitor and its Interaction with Trypsin
4. The 2.5 Å X-Ray Crystal Structure of the Acid-Stable Proteinase Inhibitor from Human Mucous Secretions Analyzed in its Complex with Bovine α-Chymotrypsin
5. Structure of the Complex of Streptomyces griseus Proteinase B and Polypeptide Chymotrypsin Inhibitor-1 from Russet Burbank Potato Tubers at 2.1 Å Resolution
6. The Refined 2.0 Å X-Ray Crystal Structure of the Complex Formed Between Bovine β-Trypsin and CMTI-I, a Trypsin Inhibitor from Squash Seeds (Cucurbita maxima). Topological Similarity of the Squash Seed Inhibitors with the Carboxypeptidase A Inhibitor from Potatoes
7. The Structure of a Complex of Recombinant Hirudin and Human α-Thrombin
8. Crystal Structure of the Thrombin-Hirudin Complex a Novel Mode of Serine Proteinase Inhibition
9. The 2.0 Å X-Ray Crystal Structure of Chicken Egg White Cystatin and its Possible Mode of Interaction with Cysteine Proteinases
10. The Refined 2.4 Å X-Ray Crystal Structure of Recombinant Human Stefin B in Complex with the Cysteine Proteinase Papain: a Novel Type of Proteinase Inhibitor Interaction
11. Protein Inhibitors of Proteinases
12. Structural Basis of the Activation and Action of Trypsin
13. 1-Antitrypsin for Structure and Functions of Serpins
14. Refined 1.2 Å Crystal Structure of the Complex Formed Between Subtilisin Carlsberg and the Inhibitor Eglin C. Molecular Structure of Eglin C and its Detailed Interaction with Subtilisin
15. Comparison of Two Highly Refined Structures of Bovine Pancreatic Trypsin Inhibitor
16. Structural Effects Induced by Removal of a Disulfide-Bridge. The X-Ray Structure of the C30A/C51A Mutant of Basic Pancreatic Trypsin Inhibitor at 1.6 Å
17. Crystallographic Refinement of Japanese Quail Ovomucoid a Kazal-Type Inhibitor and Model Building of Complexes with Serine Proteinases
18. Crystal and Molecular Structure of Chymotrypsin Inhibitor 2 from Barley Seeds in Complex with Subtilisin Novo
19. Protein Structures in Solution by Nuclear Magnetic Resonance and Distance Geometry; the Polypeptide Fold of the Basic Pancreatic Trypsin Inhibitor Determined Using Two Different Algorithms, DISGEO and DISMAN
20. Comparison of the Solution and X-Ray Structures of Barley Serine Proteinase Inhibitor 2
21. Nuclear Magnetic Resonance Solution and X-Ray Structures of Squash Trypsin Inhibitor Exhibit the Same Conformation of the Proteinase Binding Loop
22. Role of Arginine 67 in the Stabilization of Chymotrypsin Inhibitor 2: Examination of Amide Proton Exchange Rates and Denaturation Thermodynamics of an Engineered Protein
23. Mutational Analysis of a Protein-Folding Pathway
24. Kinetics and Thermodynamics of the Interaction of Proteinases with Protein Inhibitors
25. Stopped-Flow Kinetics of the Resynthesis of the Reactive Site Peptide Bond in Kallikrein. Inhibitor (Kunitz) by β-Trypsin
26. 19 …Reactiv
27. The Geometry of the Reactive Site and of the Peptide Groups in Trypsin Trypsinogen and its Complexes with Inhibitors
28. Ovomucoid Third Domains from 100 Avian Species: Isolation, Sequences, and Hypervariability of Enzyme-Inhibitor Contact Residues
29. The Refined 1.9 Å Crystal Structure of Human α-Thrombin: Interaction with DPhrProArg Chloromethylketone and Significance of the TyrProProTrp Insertion Segment
30. The Structure of Protein-Protein Recognition Sites
31. Molecular Dynamics Refinement of a Thermitase-Eglin C Complex at 1.98 Å Resolution and Comparison of Two Crystal Forms that Differ in Calcium Content
32. Two-Dimensional NMR Studies of Kazal Proteinase Inhibitors 2. Sequence-Specific Assignments and Secondary Structure of Reactive Site Modified Turkey Ovomucoid Third Domain
33. The Transition of Bovine Trypsinogen to a Trypsin-Like State upon Strong Ligand Binding. II. The Binding of the Pancreatic Trypsin Inhibitor and of Isoleucine-Valine and of Sequentially Related Peptides to Trypsinogen and to p-Guanidinobenzoate-Trypsinogen
34. Dermasterias imbricata Trypsin 1: an Enzyme which Rapidly Hydrolyzes the Reactive-Site Peptide Bonds of Protein Trypsin Inhibitors
35. 1-Proteinase Inhibitor. Crystal Structure Analysis of Two Crystal Modifications, Molecular Model and Preliminary Analysis of the Implications for Function
36. Crystal Structure of Bovine Antithrombin III
37. 1-Antichymotrypsin at 2.71 Å Resolution and its Comparison with other Serpins
38. 1-Proteinase Inhibitor
39. Crystal Structure of Ovalbumin as a Model for the Reactive Centre of Serpins
40. Plasma serine proteinase inhibitors (serpins) exhibit major conformational changes and a large increase in conformational stability upon cleavage at their reactive sites
41. 1-Proteinase Inhibitor
42. 1-Antitrypsin by a Peptide Sequentially Similar to β-Strand S4A
43. The Complete Covalent Structure of Hirudin. Localization of the Disulfide Bonds
44. Solution Structure of Recombinant Hirudin and the Lys47 → Glu Mutant: a Nuclear Magnetic Resonance and Hybrid Distance Geometry-Dynamical Simulated Annealing Study
45. Conformation of Recombinant Desulfatohirudin in Aqueous Solution Determined by Nuclear Magnetic Resonance
46. Quantitative Evaluation of the Contribution of Ionic Interactions to the Formation of the Thrombin-Hirudin Complex
47. Use of Fragments of Hirudin to Investigate Thrombin-Hirudin Interaction
48. Mechanism of Interaction of Cysteine Proteinases and Their Inhibitors as Compared to the Serine Proteinase-Inhibitor Interaction
49. Mechanism of Inhibition of Papain by Chicken Egg White Cystatin. Inhibition Constants of N-Terminally Truncated Forms and Cyanogen Bromide Fragments of the Inhibitor
50. Refined Crystal Structure of the Potato Inhibitor Complex of Carboxypeptidase A at 2.5 Å Resolution
51. Three-Dimensional Structure of Potato Carboxypeptidase Inhibitor in Solution. A Study Using Nuclear Magnetic Resonance, Distance Geometry, and Restrained Molecular Dynamics
52. Tick Anticoagulant Peptide (TAP) is a Novel Inhibitor of Blood Coagulation Factor Xa