High dose glycine nutrition affects glial cell morphology in rat hippocampus and cerebellum

International Journal of Neuropsychopharmacology

Volumn 2, Issue 1, 1999, Pages 35-40

  Shoham, S ^a   Javitt, D C ^b   Heresco Levy, U ^a,c  

^a HERZOG HOSPITAL   (Israel)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c HEBREW UNIVERSITY   (Israel)

Author keywords

Cerebellum; Glycine; Hippocampus; NMDA receptors; Schizophrenia

Indexed keywords

EID: 0001838392     PISSN: 14611457     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1461145799001285     Document Type: Article

References (26)

1. Alcantara AA, Pfenninger KH, Greenough WT (1992). 5B4-CAM expression parallels neurite outgrowth and synaptogenesis in the developing rat brain. Journal of Comparative Neurology 319, 337-348.
2. Chesler M, Kaila K (1992). Modulation of pH by neuronal activity. Trends in Neurosciences 15, 396-402.
3. Conti F, Debiasi S, Minelli A, Melone M (1996). Expression of NR1 and NR2A/B subunits of the NMDA receptor in cortical astrocytes. Glia 17, 254-258.
4. 3H]Gly uptake in rat hippocampus: kinetic analysis and autoradiographic localization. Brain Research 572, 154-163.
5. Hariharam M, Naga S, Van Noord T (1993). Systematic approach to the development of plasma amino acid analysis by high-performance liquid chromatography with ultraviolet detection with precolumn derivatization using phenyl isothiocyanate. Journal of Chromatography 621, 15-22.
6. Heresco-Levy U, Javitt DC (1998). The role of N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission in the pathophysiology and therapeutics of psychiatric syndrome. European Neuropsychopharmacology 8, 141-152.
7. Heresco-Levy U, Silipo G, Javitt DC (1996). Glycinergic augmentation of NMDA receptor-mediated neurotransmission in the treatment of schizophrenia. Psychopharmacohgy Bulletin 32, 731-740.
8. Honer M, Benke D, Laube B, Kuhse J, Heckendorn R, Allgeier H, Angst C, Monyer H, Seeburg PH, Betz H, Mohler H (1998). Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors. Journal of Biological Chemistry 273, 11158-11163.
9. Javitt DC, Zukin SR (1991). Recent advances in the phencyclidine model of schizophrenia. American Journal of Psychiatry 148, 1301-1308.
10. Jones TA, Hawrylak N, Greenough WT (1996). Rapid laminar-dependent changes in GFAP immunoreactive astrocytes in the visual cortex of rats reared in a complex environment. Psychoneuroendocrinology 21, 189-201.
11. Landry CF, Watson JB, Kashima T, Campagnoni AT (1994). Cellular influences on RNA sorting in neurons and glia: an in situ hybridization histochemical study. Molecular Brain Research 27, 1-11.
12. McDonald JW, Johnston MV (1990). Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Research Reviews 15, 41-70.
13. Magnusson KR (1996). Distributions of taurine, glutamate, and glutamate receptors during post-natal development and plasticity in the rat brain. Advances in Experimental Medical Biology 403, 435-444.
14. Malhorta AK, Finals DA, Adler CM, Elman I, Clifton A, Pickar D, Breier A (1997). Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology 17, 141-150.
15. Meshul CK, Seil FJ, Herndon RM (1987). Astrocytes play a role in regulation of synaptic density. Brain Research 402, 139-145.
16. Monyer H, Bumashev N, Laurie DJ, Sakmann B, Seeburg PH (1994). Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12, 529-40.
17. Nakajima K, Kohsaka S (1993). Functional roles of microglia in the brain. Neuroscience Research 17, 187-203.
18. Newell DW, Barth A, Ricciardi TN, Malouf AT (1997). Glycine causes increased excitability and neurotoxicity by activation of NMDA receptors in the hippocampus. Experimental Neurology 165, 235-244.
19. Oldendorph WM (1971). Brain uptake of radiolabeled amino acids, amines and hexoses after arterial injection. American Journal of Physiology 224, 1629-1639.
20. Sato K, Yoshida S, Fujiwara K, Tada K, Tohyama M (1991). Glycine cleavage system in astrocytes. Brain Research 567, 64-70.
21. Schell MJ, Molliver ME, Snyder SH (1995). D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. Proceedings of the National Academy of Sciences, USA 92, 3948-3952.
22. Shao Y, McCarthy KD (1994). Plasticity of astrocytes. Glia 11, 147-155.
23. Sirevaag AM, Black JR, Greenough WT (1991). Astrocyte hypertrophy in the dentate gyrus of young male rats reflects variation of individual stress rather than group environmental complexity manipulations. Experimental Neurology 111, 74-79.
24. Tamminga CA, Holocomb HH, Gao XM, Lahti AC (1995). Glutamate pharmacology and the treatment of schizophrenia: current status and future directions. International Clinical Psychopharmacology 10, Suppl. 3, 29-37.
25. Toth E, Lajtha A (1986). Antagonism of phencyclidine-induced hyperactivity by glycine in mice. Neurochemistry Research 11, 393-400.
26. Zafra F, Aragon C, Olivares L, Danbolt NC, Gimenez C, Storm-Mathisen J (1995). Glycine transporters are differentially expressed among CNS cells. Journal of Neuroscience 15, 3952-3969.