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Volumn 14, Issue 4, 1997, Pages 150-154

Molecular and genetic aspects of resistance to azoles in Candida albicans;Aspectos moleculares y genéticos de la resistencia a azoles en Candida albicans

Author keywords

Azoles; Candida albicans; Fluconazole; Resistance; Transporters

Indexed keywords

ARTICLE;

EID: 0001766407     PISSN: 11301406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (5)

References (47)
  • 1
    • 0001453508 scopus 로고
    • Fungal infection rates are increasing
    • Fox JL. Fungal infection rates are increasing. ASM News 1993; 10 515-518.
    • (1993) ASM News , vol.10 , pp. 515-518
    • Fox, J.L.1
  • 2
    • 0026062881 scopus 로고
    • Major trends in the microbial etiology of nosocomial infection
    • Shaberg DR, Culver DH, Gaynes RP. Major trends in the microbial etiology of nosocomial infection Am J Med 1991;91(Suppl 3B). 723-53.
    • (1991) Am J Med , vol.91 , Issue.SUPPL. 3B , pp. 723-753
    • Shaberg, D.R.1    Culver, D.H.2    Gaynes, R.P.3
  • 4
    • 0001902681 scopus 로고    scopus 로고
    • Antimicrobial agents: Antifungal agents
    • Gilman AG, Rall TW, Sies AS, Taylor P (Eds.) Elmsford. Pergamon Press
    • Bennett JE. Antimicrobial agents: antifungal agents. In Gilman AG, Rall TW, Sies AS, Taylor P (Eds.) Goodman and Gilman's the pharmacological basis of therapeutics. Elmsford. Pergamon Press, 1996: 1165-1181.
    • (1996) Goodman and Gilman's the Pharmacological Basis of Therapeutics , pp. 1165-1181
    • Bennett, J.E.1
  • 5
    • 2742615978 scopus 로고    scopus 로고
    • Anfotericina B complejo lipídico (ABLC): Nueva formulación de un antifúngico clásico
    • Madrenys i Brunet N, Torres-Rodríguez JM. Anfotericina B complejo lipídico (ABLC): Nueva formulación de un antifúngico clásico. Rev Iberoam Micol 1996; 13 (Supl 2): S95-S100.
    • (1996) Rev Iberoam Micol , vol.13 , Issue.2 SUPPL.
    • Madrenys i Brunet, N.1    Torres-Rodríguez, J.M.2
  • 6
    • 0002115088 scopus 로고
    • Differential effects of cholesterol and lanosterol on artificial membranes
    • Yeagle PL, Martin RB, Lala AK, Block K. Differential effects of cholesterol and lanosterol on artificial membranes. Proc Natl Acad Sci USA 1977: 74, 4924-4926
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 4924-4926
    • Yeagle, P.L.1    Martin, R.B.2    Lala, A.K.3    Block, K.4
  • 7
    • 0027253440 scopus 로고
    • Fluconazole resistance in Candida in patients with AIDS-a therapeutic approach
    • Ng TT, Denning DW. Fluconazole resistance in Candida in patients with AIDS-a therapeutic approach. J Infect 1993; 26 117-125.
    • (1993) J Infect , vol.26 , pp. 117-125
    • Ng, T.T.1    Denning, D.W.2
  • 8
    • 0021110866 scopus 로고
    • Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: Experience with twenty-one patients
    • Horsburgh CR, Kirkpatrick CW Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience with twenty-one patients. Am J Med 1983; 74: 23-29.
    • (1983) Am J Med , vol.74 , pp. 23-29
    • Horsburgh, C.R.1    Kirkpatrick, C.W.2
  • 9
    • 0020695681 scopus 로고
    • Modified response to ketoconazole of Candida albicans from a treatment failure
    • Warnock DW, Johnson EM, Richardson MD, Vickers CFH. Modified response to ketoconazole of Candida albicans from a treatment failure. Lancet 1983; i: 642-643.
    • (1983) Lancet , vol.1 , pp. 642-643
    • Warnock, D.W.1    Johnson, E.M.2    Richardson, M.D.3    Vickers, C.F.H.4
  • 10
    • 0028275770 scopus 로고
    • Fluconazole-resistant candidosis in an HIV cohort
    • Baily GG, Perry FM, Denning DW. Mandal BK Fluconazole-resistant candidosis in an HIV cohort. AIDS 1994; 8: 787-792
    • (1994) AIDS , vol.8 , pp. 787-792
    • Baily, G.G.1    Perry, F.M.2    Denning, D.W.3    Mandal, B.K.4
  • 12
    • 0027159764 scopus 로고
    • Resistance of yeasts to azolederivative antifungals
    • Odds FC. Resistance of yeasts to azolederivative antifungals. J Antimicrob Chemother 1993; 31 463-471.
    • (1993) J Antimicrob Chemother , vol.31 , pp. 463-471
    • Odds, F.C.1
  • 14
    • 0027730156 scopus 로고
    • Resistance of Candida albicans to azole antifungal agents
    • Hitchcock CA. Resistance of Candida albicans to azole antifungal agents. Biochem Soc Trans 1993, 21: 1039-1047
    • (1993) Biochem Soc Trans , vol.21 , pp. 1039-1047
    • Hitchcock, C.A.1
  • 15
    • 0025189969 scopus 로고
    • Mutation in cytochrome P-450-dependent 14 alpha-demethylase results in decreased affinity for azole antifungals
    • Vanden Bossohe H, Marichal P, Gorrens J, Bellens D, Moereels H, Janssen PA Mutation in cytochrome P-450-dependent 14 alpha-demethylase results in decreased affinity for azole antifungals. Biochem Soc Trans 1990: 18: 56-59.
    • (1990) Biochem Soc Trans , vol.18 , pp. 56-59
    • Vanden Bossohe, H.1    Marichal, P.2    Gorrens, J.3    Bellens, D.4    Moereels, H.5    Janssen, P.A.6
  • 16
    • 0023515339 scopus 로고
    • Sterols in Candida albicans mutants resistant to polyene or azole antifungals, and of a double mutant C albicans 6.4
    • Hitchcock CA, Russell NJ, Barrett-Bee KJ Sterols in Candida albicans mutants resistant to polyene or azole antifungals, and of a double mutant C albicans 6.4 Crit Rev Microbiol 1987; 15. 111-115.
    • (1987) Crit Rev Microbiol , vol.15 , pp. 111-115
    • Hitchcock, C.A.1    Russell, N.J.2    Barrett-Bee, K.J.3
  • 19
    • 0022539316 scopus 로고
    • The lipid composition of azole-sensitive and azole-resistant strains of Candida albicans
    • Hitchcock CA, Barrett BK, Russell NJ The lipid composition of azole-sensitive and azole-resistant strains of Candida albicans. J Gen Microbiol 1986; 132: 2421-2431
    • (1986) J Gen Microbiol , vol.132 , pp. 2421-2431
    • Hitchcock, C.A.1    Barrett, B.K.2    Russell, N.J.3
  • 20
    • 84907123977 scopus 로고
    • The lipid composition and permeability to azole of an azole- And polyene-resistant mutant of Candida albicans
    • Hitchcock CA, Barrett-Bee KJ, Russell NJ. The lipid composition and permeability to azole of an azole- and polyene-resistant mutant of Candida albicans. J Med Vet Mycol 1987; 25: 29-37.
    • (1987) J Med Vet Mycol , vol.25 , pp. 29-37
    • Hitchcock, C.A.1    Barrett-Bee, K.J.2    Russell, N.J.3
  • 21
    • 0026588343 scopus 로고
    • Active efflux mechanisms for antimicrobial resistance
    • Levy SB. Active efflux mechanisms for antimicrobial resistance. Antimicrob Agents Chemother 1992; 4: 695-703.
    • (1992) Antimicrob Agents Chemother , vol.4 , pp. 695-703
    • Levy, S.B.1
  • 23
    • 0025127211 scopus 로고
    • Genetics of Candida albicans
    • Scherer S, Magee PT. Genetics of Candida albicans. Microbiol Rev 1990; 54: 226-241.
    • (1990) Microbiol Rev , vol.54 , pp. 226-241
    • Scherer, S.1    Magee, P.T.2
  • 25
    • 0028791464 scopus 로고
    • Cloning of the Candida albicans HIS1 gene by direct complementation of a C. albicans histidine auxotroph using an improved double-ARS shuttle vector
    • Pla J, Pérez-Diaz RM, Navarro-García F, Sánchez M, Nombela C. Cloning of the Candida albicans HIS1 gene by direct complementation of a C. albicans histidine auxotroph using an improved double-ARS shuttle vector Gene 1995; 165, 115-120.
    • (1995) Gene , vol.165 , pp. 115-120
    • Pla, J.1    Pérez-Diaz, R.M.2    Navarro-García, F.3    Sánchez, M.4    Nombela, C.5
  • 26
    • 0026032297 scopus 로고
    • Multiple or pleiotropic drug resistance in yeast
    • Balzi E, Goffeau A Multiple or pleiotropic drug resistance in yeast. Biochim Biophys Acta 1991; 1073: 241-252.
    • (1991) Biochim Biophys Acta , vol.1073 , pp. 241-252
    • Balzi, E.1    Goffeau, A.2
  • 27
    • 0028067028 scopus 로고
    • Genetics and biochemistry of yeast multidrug resistance
    • Balzi E, Goffeau A. Genetics and biochemistry of yeast multidrug resistance. Biochim Biophys Acta 1994; 1187: 152-162.
    • (1994) Biochim Biophys Acta , vol.1187 , pp. 152-162
    • Balzi, E.1    Goffeau, A.2
  • 28
    • 0028932101 scopus 로고
    • Yeast multidrug resistance, the PDR network
    • Balzi E, Goffeau A. Yeast multidrug resistance, the PDR network. J Bioenerg Biomembr 1995; 27: 71-76.
    • (1995) J Bioenerg Biomembr , vol.27 , pp. 71-76
    • Balzi, E.1    Goffeau, A.2
  • 29
    • 0025774660 scopus 로고
    • Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate
    • Fling ME, Kopf J, Tamarkin A, Gorman JA, Smith HA, Koltin Y. Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate. Mol Gen Genet 1991; 227: 318-329.
    • (1991) Mol Gen Genet , vol.227 , pp. 318-329
    • Fling, M.E.1    Kopf, J.2    Tamarkin, A.3    Gorman, J.A.4    Smith, H.A.5    Koltin, Y.6
  • 30
  • 31
    • 0027507306 scopus 로고
    • A major superfamily of transmembrane facilitators that catalyse uniport. symport and antiport
    • Marger MD, Saier MH. A major superfamily of transmembrane facilitators that catalyse uniport. symport and antiport. Trends Biochem Sci 1993; 18: 13-20.
    • (1993) Trends Biochem Sci , vol.18 , pp. 13-20
    • Marger, M.D.1    Saier, M.H.2
  • 32
    • 0026708261 scopus 로고
    • Cloning and sequence analysis of a Candida maltosa gene which confers resistance to cycloheximide
    • Sasnauskas K, Jomantiene R, Lebediene E, Lebedys J, Januska A, Janulaitis A. Cloning and sequence analysis of a Candida maltosa gene which confers resistance to cycloheximide Gene 1992, 116: 105-108.
    • (1992) Gene , vol.116 , pp. 105-108
    • Sasnauskas, K.1    Jomantiene, R.2    Lebediene, E.3    Lebedys, J.4    Januska, A.5    Janulaitis, A.6
  • 33
    • 0027372484 scopus 로고
    • The amilonde resistance gene, car1. of Schizosaccharomyces pombe
    • Jia Z-P, McCullough N, Wong L, Young PG. The amilonde resistance gene, car1. of Schizosaccharomyces pombe Mol Gen Genet 1993; 241: 298-304.
    • (1993) Mol Gen Genet , vol.241 , pp. 298-304
    • Jia, Z.-P.1    McCullough, N.2    Wong, L.3    Young, P.G.4
  • 34
    • 0028844181 scopus 로고
    • Reduced virulence of Candida albicans mutants affected in multidrug resistance
    • Becker JM Henry LK, Jiang W. Koltin Y Reduced virulence of Candida albicans mutants affected in multidrug resistance. Infect Immun 1995; 63: 4515-4518.
    • (1995) Infect Immun , vol.63 , pp. 4515-4518
    • Becker, J.M.1    Henry, L.K.2    Jiang, W.3    Koltin, Y.4
  • 36
    • 0029820482 scopus 로고    scopus 로고
    • Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors
    • Sanglard D, Ischer F, Monod M, Bille J. Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors. Antimicrob Agents Chemother 1996: 10: 2300-2305.
    • (1996) Antimicrob Agents Chemother , vol.10 , pp. 2300-2305
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 37
    • 0028928549 scopus 로고
    • Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals
    • Prasad R, De Wergifosse P, Goffeau A, Balzi E. Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals. Curr Genet 1995, 27: 320-329.
    • (1995) Curr Genet , vol.27 , pp. 320-329
    • Prasad, R.1    De Wergifosse, P.2    Goffeau, A.3    Balzi, E.4
  • 38
    • 0028082188 scopus 로고
    • PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1
    • Balzi E, Wang M, Leterme S, Van Dyck L, Goffeau A. PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J Biol Chem 1994, 269: 2206-2214.
    • (1994) J Biol Chem , vol.269 , pp. 2206-2214
    • Balzi, E.1    Wang, M.2    Leterme, S.3    Van Dyck, L.4    Goffeau, A.5
  • 39
    • 0027497594 scopus 로고
    • Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases
    • Servos J, Haase E, Brendel M. Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases. Mol Gen Genet 1993; 236: 214-218.
    • (1993) Mol Gen Genet , vol.236 , pp. 214-218
    • Servos, J.1    Haase, E.2    Brendel, M.3
  • 40
    • 0025237430 scopus 로고
    • Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces
    • Leppert G, McDevitt R, Falco SC, Van Dyk TK, Ficke MB, Golin J. Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces. Genetics 1990; 125: 13-20.
    • (1990) Genetics , vol.125 , pp. 13-20
    • Leppert, G.1    McDevitt, R.2    Falco, S.C.3    Van Dyk, T.K.4    Ficke, M.B.5    Golin, J.6
  • 41
    • 0026605537 scopus 로고
    • CLUSTAL V. Improved software for multiple sequence alignment
    • Higgins DG, Bleasby AJ, Fuchs R, CLUSTAL V. Improved software for multiple sequence alignment. Comput Appl Biosci 1992; 2: 189-191.
    • (1992) Comput Appl Biosci , vol.2 , pp. 189-191
    • Higgins, D.G.1    Bleasby, A.J.2    Fuchs, R.3
  • 42
    • 0029164287 scopus 로고
    • The ABC of channel regulation
    • Higgins CF. The ABC of channel regulation Cell 1995, 82: 693-696.
    • (1995) Cell , vol.82 , pp. 693-696
    • Higgins, C.F.1
  • 43
    • 0028793725 scopus 로고
    • Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
    • Sanglard D, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J. Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters. Antimicrob Agents Chemother 1995; 39: 2378-2386.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2378-2386
    • Sanglard, D.1    Kuchler, K.2    Ischer, F.3    Pagani, J.L.4    Monod, M.5    Bille, J.6
  • 44
    • 0031047670 scopus 로고    scopus 로고
    • Cloning of Candida albicans genes conferring resistance to azole antifungal agents: Characterization of CDR2, a new multidrug ABC transporter gene
    • Sanglard D, Ischer F, Monod M, Bille J. Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene. Microbiology 1997; 143:405-416.
    • (1997) Microbiology , vol.143 , pp. 405-416
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 45
    • 0029853191 scopus 로고    scopus 로고
    • Multiple eflux mechanisms are involved in Candida albicans fluconazole resistance
    • Albertson GD, Niimi M, Cannon R, Jenkinson HF. Multiple eflux mechanisms are involved in Candida albicans fluconazole resistance. Antimicrob Agents Chemother 1996; 40: 2835-2841.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2835-2841
    • Albertson, G.D.1    Niimi, M.2    Cannon, R.3    Jenkinson, H.F.4
  • 46
    • 0028352302 scopus 로고
    • Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast
    • Decottignies A, Kolaczkowski M, Balzi E, Goffeau A. Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast. J Biol Chem 1994; 269: 12797-12803.
    • (1994) J Biol Chem , vol.269 , pp. 12797-12803
    • Decottignies, A.1    Kolaczkowski, M.2    Balzi, E.3    Goffeau, A.4
  • 47
    • 0026602838 scopus 로고
    • Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5
    • Meyers S, Schauer W, Balzi E, Wagner M, Goffeau A, Golin J. Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5. Curr Genet 1992; 21: 431-436.
    • (1992) Curr Genet , vol.21 , pp. 431-436
    • Meyers, S.1    Schauer, W.2    Balzi, E.3    Wagner, M.4    Goffeau, A.5    Golin, J.6


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