A formal synthesis of (+)-α-allokainic acid via sulfanyl radical addition-cyclization reaction

Heterocycles

Volumn 46, Issue 1, 1997, Pages 321-333

  Miyata, Okiko ^a   Ozawa, Yoshiki ^a   Ninomiya, Ichiya ^a   Aoe, Keiichi ^b   Hiramatsu, Hajime ^b   Naito, Takeaki ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001765135     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-97-s18     Document Type: Article

References (15)

1. Review: A. F. Parsons, Tetrahedron, 1996, 52, 4149.
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3. b) T. Naito, Y. Honda, O. Miyata, and I. Ninomiya, Chem. Pharm. Bull., 1993, 41, 217.
4. The sulfanyl radical addition-cyclization-elimination reaction for (-)-α-kainic acid.; O. Miyata, Y. Ozawa, I. Ninomiya, and T. Naito, Synlett, 1997, in press.
5. The sulfanyl radical addition-cyclization reaction for lactone synthesis; a) O. Miyata, A. Nishiguchi., I. Ninomiya, T. Naito, K. Aoe, and K. Okamura, Tetrahedron Lett., 1996, 37, 229.
6. b) O. Miyata, A. Nishiguchi, I. Ninomiya, and T. Naito, Chem. Pharm. Bull., 1996, 44, 1285.
7. S. Katsumura, N. Yamamoto, M. Morita, and Q. Han, Tetrahedron: Asymmetry, 1994, 5, 161.
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14. 9 has reported synthesis of (+)-α-allokainic acid via the ketone ((-)-16) and the olefin ((+)-17).
15. S. Hatakeyama, K. Sugawara, and S. Takano, J. Chem. Soc., Chem. Commun., 1993, 125.