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Volumn 37, Issue 7, 1998, Pages 1592-1597

Design and Synthesis of a Transition Metal Responsive Semisynthetic Myoglobin-Bearing Iminodiacetic Acid Moiety

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EID: 0001736235     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic961474v     Document Type: Article
Times cited : (19)

References (45)
  • 1
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    • (1976) The Enzymes , vol.13 , pp. 345
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  • 16
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    • Fleischer, S., Packer. L., Eds.; Academic Press: New York, 1978: Part C
    • (a) Asakura, T. In Methods in Enzymology; Fleischer, S., Packer. L., Eds.; Academic Press: New York, 1978: Part C, p 446,
    • (1978) Methods in Enzymology , pp. 446
    • Asakura, T.1
  • 19
    • 85087248376 scopus 로고    scopus 로고
    • note
    • -1).
  • 22
    • 1542705827 scopus 로고    scopus 로고
    • note
    • Curves of the pH titration of IDAn-heme incorporated in Triton X-100 micelle instead of apo-Mb did not change by addition of any transition metals.
  • 23
    • 1542391273 scopus 로고    scopus 로고
    • note
    • This indicates that iminodiacetic acid modification scarcely disturbs the Mb active site, which may be explained by the net anionic charge of iminodiacetic acid moiety and the less bulkiness, like the native propionate ends.
  • 24
    • 85087250538 scopus 로고    scopus 로고
    • note
    • a values are determined under the condition where more than 99% of IDAn-Mb's bind the corresponding transition metals.
  • 25
    • 85087249092 scopus 로고    scopus 로고
    • note
    • - -bound IDAn-Mb's do not show any UV-visible change upon addition of metal cations.
  • 28
    • 0023912972 scopus 로고
    • a values without metals, CD spectra, the stability of oxy-Mb, and the redox potentials suggest that the distal pocket is not significantly perturbed by the heme modification with IDAn.
    • (1988) J. Am. Chem. Soc. , vol.110 , pp. 4176
    • Emerson, S.D.1    Lecomte, G.N.2    La Mar, G.N.3
  • 29
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    • note
    • -1).
  • 32
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    • note
    • 2+ are omitted.
  • 37
    • 85087247425 scopus 로고    scopus 로고
    • note
    • 2+ -bound IDA2-Mb, suggesting that the metal cation induced electrostatic effect may partially contribute to the rate acceleration.
  • 38
    • 1542705817 scopus 로고    scopus 로고
    • Noncovalent interactions of enzymes with some crown ethers have been reported: (a) Reinhoudt, D. N.; Egendebak, A. M.; Nigenhuis, W. F.; Verboom, W.; Kloosterman, M.; Schoemarker, H. E. J. Chem. Soc., Chem. Commun. 1996, 2205. (b) Nagasaki, T.; Kimura. O.; Ukon, M.; Arimori. S.; Hamachi, I.; Shinkai. S. J. Chem. Soc., Perkin Trans. 1 1994, 75, (c) Itoh, T.; Takagi, Y.; Murukumi, T.; Hiyama, Y.; Tsukube, H. J. Org. Chem. 1996, 61, 2158.
    • (1996) J. Chem. Soc., Chem. Commun. , pp. 2205
    • Reinhoudt, D.N.1    Egendebak, A.M.2    Nigenhuis, W.F.3    Verboom, W.4    Kloosterman, M.5    Schoemarker, H.E.6
  • 39
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    • Noncovalent interactions of enzymes with some crown ethers have been reported: (a) Reinhoudt, D. N.; Egendebak, A. M.; Nigenhuis, W. F.; Verboom, W.; Kloosterman, M.; Schoemarker, H. E. J. Chem. Soc., Chem. Commun. 1996, 2205. (b) Nagasaki, T.; Kimura. O.; Ukon, M.; Arimori. S.; Hamachi, I.; Shinkai. S. J. Chem. Soc., Perkin Trans. 1 1994, 75, (c) Itoh, T.; Takagi, Y.; Murukumi, T.; Hiyama, Y.; Tsukube, H. J. Org. Chem. 1996, 61, 2158.
    • (1994) J. Chem. Soc., Perkin Trans. 1 , pp. 75
    • Nagasaki, T.1    Kimura, O.2    Ukon, M.3    Arimori, S.4    Hamachi, I.5    Shinkai, S.6
  • 40
    • 0001319374 scopus 로고    scopus 로고
    • Noncovalent interactions of enzymes with some crown ethers have been reported: (a) Reinhoudt, D. N.; Egendebak, A. M.; Nigenhuis, W. F.; Verboom, W.; Kloosterman, M.; Schoemarker, H. E. J. Chem. Soc., Chem. Commun. 1996, 2205. (b) Nagasaki, T.; Kimura. O.; Ukon, M.; Arimori. S.; Hamachi, I.; Shinkai. S. J. Chem. Soc., Perkin Trans. 1 1994, 75, (c) Itoh, T.; Takagi, Y.; Murukumi, T.; Hiyama, Y.; Tsukube, H. J. Org. Chem. 1996, 61, 2158.
    • (1996) J. Org. Chem. , vol.61 , pp. 2158
    • Itoh, T.1    Takagi, Y.2    Murukumi, T.3    Hiyama, Y.4    Tsukube, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.