β-amyloid protein modulates the vascular activity of acetylcholine at the level of the microvasculature

Alzheimer's Reports

Volumn 1, Issue 4, 1998, Pages 233-239

  Poliviou, Helen ^a   Zeinab Khalil, C A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001639665     PISSN: 14616130     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Alvarez A, Opazo C, Alarcon R et al. (1997). Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils. J Mol Biol 272, 348-361.
2. Aruoma OI, Halliwell B et al. (1989). The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radic Biol Med 6, 593-597.
3. Beal MF (1995). Aging, energy and oxidative stress in neurodegenerative disease. Ann Neurol 38, 357-366.
4. Choi BH (1993). Oxygen, Antioxidants and brain dysfunction. Yonsei Med J 34, 1-10.
5. Efthimiopoulos SVD, Rippellini JA, Tezapsidis N and Robakis NK (1996). Cholinergic agonist stimulate secretion of soluble full length amyloid precursor protein in neuroendocrine cells. Proc Natl Acad Sci USA 93, 8046-8050.
6. Gillissen A, Scharling B et al. (1997). Oxidant scavenger function of ambroxol in vitro: a comparison with N-acetylcysteine. Res Exp Med Berl 196, 389-398.
7. Grammas P, Botchlet T et al. (1995). Alzheimer disease amyloid proteins inhibit brain endothelial cell proliferation in vitro. Dementia 6, 126-130.
8. Growdon JH (1997). Muscarinic agonist in Alzheimer's disease. Life Sciences 60, 993-998.
9. Hoffer, E., I. Avidor, et al. (1993). N-acetylcysteine delays the infiltration of inflammatory cells into the lungs of paraquatintoxicated rats. Toxicol Appl Pharmacol 120, 8-12.
10. Hong XJ, Francker A et al. (1991). Effects of N-acetylcysteine on histamine release by sodium fluoride and compound 487 80 from isolated rat mast cells. Int Arch Allergy Appl Immunol 96, 338-343.
11. Hoshi M, Takashima A, Murayama M et al. (1997). Nontoxic amyloid beta peptide 1-42 suppresses acetylcholine synthesis. Possible role in cholinergic dysfunction in Alzheimer's disease. J Biol Chem 272, 2038-2041.
12. Huribal M, Kumar R et al. (1994). Endothelin-stimulated monocyte supernatants enhance neutrophil superoxide production. Shock 1, 184-187.
13. Kasemsri T and Armstead WM (1997). Endothelin production links superoxide generation to altered opioid-induced pial artery vasodilation after brain injury in pigs. Stroke 28), 190-196.
14. Khalil Z, Chen H et al. (1996). Mechanisms underlying the vascular activity of beta-amyloid protein fragment (beta A(4)25-35) at the level of skin microvasculature. Brain Res 736, 206-216.
15. Khalil Z, Sanderson K et al. (1994). Beta A4(25-35) modulates substance P effect on rat skin microvasculature in aged rats: pharmacological manipulation using SEC-receptor ligands. Brain Res 651, 227-235.
16. Kojima T, Hattori K et al. (1996). Endothelin-1 has a priming effect on production of superoxide anion by alveolar macrophages: its possible correlation with bronchopulmonary dysplasia. Pediatr Res 39, 112-116.
17. Kowall NW, Beal MF et al. (1991). An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. Proc Natl Acad Sci USA 88, 7247-7251.
18. Kowall NW, McKee AC et al. (1992). In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment. Neurobiol Aging 13, 537-542.
19. Malorni W, Rivabene R et al. (1993). N-acetylcysteine inhibits apoptosis and decreases viral particles in HIV-chronically infected U937 cells. FEBS Lett 327, 75-78.
20. Michael JR, Markewitz BA et al. (1997). Oxidant stress regulates basal endothelin-1 production by cultured rat pulmonary endothelial cells. Am J Physiol 273, L768-774.
21. Minami M, Kimura M et al. (1995). Endothelin-1-like immunoreactivity in cerebral cortex of Alzheimer-type dementia. Prog Neuropsychopharmacol Biol Psychiatry 19, 509-513.
22. Muller DM, Mendla K, Farber SA and Nitsch RM (1997). Muscurinic M1 receptor agonists increase the secretion of the amyloid precursor protein ectodomain. Life sciences 60, 985-991.
23. Pappolla MA, Omar RA et al. (1992). Immunohistochemical evidence of antioxidant stress in Alzheimer's disease. Am J Pathol 140, 621-628.
24. Pedersen WA, Kloczewiak MA and Blusztajn JK (1996). Amyloid beta-protein reduces acetyicholine synthesis in a cell line derived from cholinergic neurons of the basal forebrain. Proc Natl Acad Sci USA 93, 8068-8071.
25. Pittel Z, Heldman E, Barg J et al. (1996). Muscurinic control of amyloid precursor protein secretion in rat cerebral cortex and cerebellum. Brain Res 742, 299-304.
26. Price JM, Sutton ET et al. (1997). Beta-Amyloid induces cerebrovascular endothelial dysfunction in the rat brain. Neurol Res 19, 534-538.
27. Rosenblum WI and El Sabban F (1982). Dimethyl sulfoxide (DMSO) and glycerol, hydroxyl radical scavengers, impair platelet aggregation within and eliminate the accompanying vasodilation of, injured mouse pial arterioles. Stroke 13, 35-39.
28. Rossner SU, Yu U, Kirazov J et al. (1997). In vivo regulation of amyloid precursor protein secretion in rat neocortex by cholinergic activity. Eur J Neurosci 9, 2125-2134.
29. Schubert D, Behl C et al. (1995). Amyloid peptides are toxic via a common oxidative mechanism. Proc Natl Acad Sci USA 92, 1989-1993.
30. Thomas T, Thomas G et al. (1996). Beta-Amyloid-mediated vasoactivity and vascular endothelial damage [see comments]. Nature 380, 168-171
31. Thomas T, Sutton ET, Hellermann A and Price JM (1997a). Beta-amyloid-induced coronary artery vasoactivity and endothelial damage. J Cardiovasc Pharmacol 30, 517-522.
32. Thomas T, McLendon C et al. (1997b). Beta-Amyloid-induced cerebrovascular endothelial dysfunction. Ann N Y Acad Sci 826, 447-451.
33. Villagrasa V, Cortijo J et al. (1997). Inhibitory effects of N-acetylcysteine on superoxide anion generation in human polymorphonuclear leukocytes. J Pharm Pharmacol 49, 525-529.
34. Ward J (1994). Free radicals, antioxidants and preventative geriatrics. Aust Fam Phy 23, 1297-1305.
35. Wolin MS (1991). Activated oxygen metabolites as regulators of vascular tone. Klin Wochenschr 69, 1046-1049.
36. Yankner BA, Duffy LK et al. (1990). Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science 250, 279-282.