Reaction of proflavine derivatives with formaldehyde: Access to mono- and bis-(3,4-dihydro[1,3]oxazino)acridines of pharmacological interest

Heterocycles

Volumn 48, Issue 4, 1998, Pages 755-767

  Fixier, Noémie ^a   Demeunynck, Martine ^a   Duflos, Alain ^b   Lhomme, Jean ^a  

^a UNIVERSITÉ JOSEPH FOURIER   (France)

^b Centre d'Immunologie Pierre Fabre   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001573385     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-97-8083     Document Type: Article

References (8)

1. L. S. Lerman, J. Mol. Biol, 1961, 18;
2. S. F. Kitchen, Y. H. Wang, A. L. BauMStark, W. D. Wilson, and D. W. Boykin, J. Med. Chem., 1985, 28, 940;
3. J. M. Crenshaw, D. E. Graves, and W. A. Denny, Biochemistry, 1995, 34, 13682.
4. For a recent review article, see: L. R. Ferguson and W. A. Denny, Mutation Res., 1991, 258, 123;
5. A. Albert, "The Acridines. Their Preparation Physical, Chemical and Biological Properties and Uses", Edward Arnold publishers, London, 1966.
6. A. Duflos, D. C. H. Bigg, J. Lhomme, N. Fixier, C. Etievant, and M. Demeunynck, Pierre Fabre Médicament Patent FR 2,712,290 [Chem. Abstr., 1995, 123, 313985p];
7. J. Lhomme, D. C. H. Bigg, A. Duflos, B. Bonnaud, M. Demeunynck, C. Etievant, and R. Kiss, Pierre Fabre Médicament Patent PCT Int. App. WO 94 25,439 [Chem. Abstr., 1995, 122, 239555j];
8. A. Duflos, D. C. H. Bigg, J. Lhomme, B. Bonnaud, and C. Etievant, Pierre Fabre Médicament Patent FR 2,716,454 [Chem. Abstr., 1996, 124, 117108m]