Physicochemical characteristics of emulsions during fat digestion in human stomach and duodenum

American Journal of Physiology

Volumn 271, Issue 1 PART 1, 1996, Pages

  Armand, Martine ^a,b,c   Borel, Patrick ^a   Pasquier, Berengere ^a   Dubois, Christophe ^a   Senft, Michele ^a   Andre, Marc ^a   Peyrot, Jacques ^a   Salducci, Jacques ^a   Lairon, Denis ^a  

^a INSERM   (France)

^b CEMAGREF   (France)

^c HÔPITAL NORD   (France)

Author keywords

Droplet size measurement; Gastric lipase; Lipolysis; Pancreatic lipase

Indexed keywords

EID: 0001544869     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Armand, M., P. Borel, C. Dubois, M. Senft, J. Peyrot, J. Salducci, H. Lafont, and D. Lairon. Characterization of emulsions and lipolysis of dietary lipids in human stomach. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29):G372-G381, 1994.
2. Armand, M., P. Borel, P. Ythier, G. Dutot, C. Melin, M. Senft, H. Lafont, and D. Lairon. Effects of droplet size, triacylglycerol composition, and calcium on the hydrolysis of complex emulsions by pancreatic lipase:an in vitro study. J. Nutr. Biochem. 3:333-341,1992.
3. Bitman, J., and D. L. Wood. Quantitative densitometry in situ of lipids separated by thin layer chromatography. J. Liq. Chromatogr. 41023-1034,1981.
4. Borel, P., M. Armand, P. Ythier, G. Dutot, C. Melin, M. Senft, H. Lafont, and D. Lairon. Hydrolysis of emulsions with different triglycérides and droplet sizes by gastric lipase in vitro. Effect on pancreatic lipase activity. J. Nutr. Biochem. 5:124-133, 1994.
5. Borel, P., M.Armand, P. Ythier, G. Dutot, C. Melin, M. Senft, H. Lafont, and D. Lairon. Digestion and absorption of tubefeeding emulsions with different droplet sizes and compositions in the rat. J. Parenter. Enterai Nutr. 18:534-543, 1994.
6. Borgström, B., and H. Hildebrand. Lipase and co-lipase activities of human small intestinal contents after a liquid test meal. Scand. J. Gastroenterol. 10:585-591, 1975.
7. Carey, M. C., D. M. Small, and C. M. Bliss. Lipid digestion and absorption. Annu. Rev. Physiol. 45:651-677,1983.
8. Carrière, F., J. A. Barrowman, R. Verger, and R. Laugier. Secretion and contribution to lipolysis of gastric and pancreatic lipases during a test meal in humans. Gastroenterology 105:876-888,1993.
9. Desnuelle, P., M. J. Constantin, and J. Baldy. Technique potentiométrique pour la mesure de l'activité de la lipase pancréatique. Bull. Soc. Chim. Biol. 37:285-290,1955.
10. Folch, J., M. Lees, and J. H. G. Stanley. A simple method for thé isolation and purification of total lipids from animal tissue. J. Biol. Chem. 226:498-509,1957.
11. Frazer, A. C., J. H. Schulman, and H. C. Stewart. Emulsification of fat in thé intestine of the rat and its relationship to absorption. J. Physiol. Land. 103:306-316,1944.
12. Gargouri, Y., G. Pieroni, C. Riviere, J. F. Sauniere, P. A. Lowe, L. Sarcla, and R. Verger. Kinetic assay of human gastric lipase on short- and long-chain triacylglycerol emulsions. Gastroenterology 91:919-925,1986.
13. Hamosh, M. Lingual and Gastric Lipases:Their Role in Fat Digestion. Boca Raton, PL:CRC, 1990, p. 1-239.
14. Hamosh, M., H. Klaeveman, R. O. Wolf, and R. O. Scow. Pharyngeal lipase and digestion of dietary triglycéride in man. J. Clin. Invest. 55:908-913,1975.
15. Hernell, O., J. E. Staggers, and M. C. Carey. Physicalchemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beings. Biochemistry 29:2041-2056, 1990.
16. Hoffman, A. F., and B. Borgström. Physicochemical state of lipids in intestinal content during their digestion and absorption. J. Clin. Invest. 43:43-49,1964.
17. Holt, P. R., B. M. Fairchild, and J. Weiss. A liquid crystalline phase in human intestinal contents during fat digestion. Lipids 21:444-446,1986.
18. Hyden, S. A turbidimetric method for the determination of higher polyethylene glycols in biological materials. K. Lantbrukshogsk. Ann. 22:139-145,1955.
19. Kellow, J. E., T. J. Borody, S. F. Phillips, R. L. Tucker, and A. C. Hadda. Human interdigestive motility:variations in patterns from oesophagus to colon. Gastroenterology 91386395,1986.
20. Lairon, D., G. Nalbone, H. Lafont, J. Leonardi, J. L. Vigne, C. Chabert, J. C. Hauton, and R. Verger. Effects of bile lipids on the absorption and activity of pancreatic lipase on triacylglycerol emulsions. Biochim. Biophys. Acta 618:119-128,1980.
21. Lindström, M., H. Ljusberg-Wahren, K. Larsson, and B. Borgström. Aqueous lipid phases of relevance to intestinal fat digestion and absorption. Lipids 16:749-754,1981.
22. Linthorst, J. M., S. Bennett Clark, and P. R. Holt. Triglycéride emulsiflcation by amphipaths present in the intestinal lumen during digestion of fat. J. Colloid Interface Sei. 60:1-10,1977.
23. Malagelada, J. R., and F. Azpiroz. Determinants of gastric emptying and transit in the small intestine. In:Handbook of Physiology. The Gastrointestinal System. Motility and Circulation. Bethesda, MD:
24. Am. Physiol. Soc., 1989, sect. 6, vol. I, pt. 2, chapt. 23, p. 909-937.
25. Mansbach, C. M., R. S. Cohen, and P. B. Leff. Isolation and properties of the mixed lipid micelles present in intestinal content during fat digestion in man. J. Clin. Invest. 56:781-791, 1975.
26. Miller, K. W., and D. M. Small. Structure of triglyceride-rich lipoproteins:an analysis of core and surface phases. In:Plasma Lipoprotein, edited by A. M. Gotto. New York:Elsevier, 1987, p. 1-74.
27. Nalbone, G., D. Lairon, H. Lafont, N. Domingo, J. C. Hauton, R. Julien, and L. Sarda. Behavior of biliary phospholipids in intestinal lumen during fat digestion in rat. Lipids 9:765-770,1974.
28. Patton, J. S., and M. C. Carey. Watching fat digestion. Science Wash. DC 204:145-148,1979.
29. Prince, L. M. Emulsions and Emulsion Technology. New York:Lissant, 1974, p. 125-178.
30. Rathelot, J., R. Julien, I. Bosc-Bierne, Y. Gargouri, P. Canioni, and L. Sarda. Horse pancreatic lipase. Interaction with colipase from various species. Biochimie 63:227-234,1981.
31. Rigler, M. W., R. E. Honkanen, and J. S. Patton. Visualization by freeze fracture, in vitro and in vivo, of the products of fat digestion. J. Lipid Res. 27:836-857,1986.
32. Rouser, G., G. Kritchevsky, and A. Yamamoto. Lipid Chromatographie Analysis. New York:Dekker, 1967, vol. 1, p. 99-162.
33. Small, D. M. The Physical Chemistry ofLipids fromAlkanes to Phospholipids. New York:Plenum, 1986, p. 1-651.
34. Staggers, J. E., O. Hernell, and M. C. Carey. Physicalchemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings. Biochemistry 2920282040,1990.
35. Verger, R. Pancreatic lipases. In:Lipases, edited by B. Borgström and H. L. Brockman. New York:Elsevier, 1984, p. 84-150.