Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-D-aspartate-induced necrosis in mouse cortical neurons

Journal of Neurochemistry

Volumn 74, Issue 6, 2000, Pages 2455-2461

  Ko, Hyuk Wan ^a   Han, Kong Sook ^a   Kim, Eun Young ^a   Ryu, Bo Rum ^a   Yoon, Won Joo ^a   Jung, Yong Keun ^b   Kim, Seong Up ^a   Gwag, Byoung Joo ^a  

^a Ajou University School of Medicine   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Apoptosis; Calyculin A; Caspase 3; Necrosis; p38; Tau

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALYCULIN A; CASPASE 3; CASPASE INHIBITOR; CYCLOHEXIMIDE; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYLOXYCARBONYLVALINYLALANYLASPARTIDYLFLUOROMETHYL KETONE; N METHYL DEXTRO ASPARTIC ACID; SYNAPTOPHYSIN; TAU PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN PROTECTION; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; CASPASE 3; CASPASES; CELLS, CULTURED; CEREBRAL CORTEX; CYSTEINE PROTEINASE INHIBITORS; DRUG SYNERGISM; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; FETUS; IMIDAZOLES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; N-METHYLASPARTATE; NECROSIS; NEURONS; NEUROTOXINS; OXAZOLES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, N-METHYL-D-ASPARTATE; TAU PROTEINS;

ANIMALIA;

EID: 0001533313     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0742455.x     Document Type: Article

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