On-line deconjugation of glucuronides using an immobilized enzyme reactor based upon β-glucuronidase

Journal of Chromatography B: Biomedical Applications

Volumn 715, Issue 2, 1998, Pages 379-386

  Pasternyk Di Marco, Marika ^a   Felix, Guy ^b   Descorps, Vincent ^b   Ducharme, Murray P ^a   Wainer, Irving W ^a,c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Ecole Nationale Superieure de Chimie et de Physique de Bordeaux   (France)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

Glucuronidase; Enzymes; Glucuronides; Immobilized enzyme reactor; On line deconjugation

Indexed keywords

BETA GLUCURONIDASE; CHLORAMPHENICOL; ESTRADIOL; HYMECROMONE; IMMOBILIZED ENZYME; MORPHINE; PARACETAMOL; PHENOL; ZIDOVUDINE;

ARTICLE; CHEMICAL MODIFICATION; DRUG DETERMINATION; DRUG GLUCURONIDATION; ENZYME ACTIVITY; IMMOBILIZATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CHLORAMPHENICOL; ENZYMES, IMMOBILIZED; GLUCURONATES; GLUCURONIDASE; HEAT; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; REPRODUCIBILITY OF RESULTS; SUBSTRATE SPECIFICITY;

EID: 0001525460     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(98)00229-1     Document Type: Article

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