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Volumn 1, Issue 3, 1998, Pages 180-187

Androgen exposure and the maintenance of skeletal integrity in aging men

Author keywords

Androgens; Dihydrotestosterone; Men; Osteoporosis; Rat; Testosterone

Indexed keywords


EID: 0001521849     PISSN: 13685538     EISSN: None     Source Type: Journal    
DOI: 10.3109/13685539809146106     Document Type: Review
Times cited : (8)

References (59)
  • 1
    • 0031955217 scopus 로고    scopus 로고
    • A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men
    • Riggs B, Khosla S, Melton J. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res 1998;13:763-73
    • (1998) J Bone Miner Res , vol.13 , pp. 763-773
    • Riggs, B.1    Khosla, S.2    Melton, J.3
  • 4
    • 0025881025 scopus 로고
    • High-affinity androgen binding and androgenic regulation of alfa1(I)-procollagen and transforming growth factor-β steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells
    • Benz D, Haussler M, Thomas M, Speelman B, Komm B. High-affinity androgen binding and androgenic regulation of alfa1(I)-procollagen and transforming growth factor-β steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells. Endocrinology 1991;128: 2723-30
    • (1991) Endocrinology , vol.128 , pp. 2723-2730
    • Benz, D.1    Haussler, M.2    Thomas, M.3    Speelman, B.4    Komm, B.5
  • 5
    • 0027068231 scopus 로고
    • Characteristics of steroid hormone receptors in cultured LC3T3-E1 osteoblastic cells and effect of steroid hormones on cell proliferation
    • Masuyama A, Ouchi Y, Sato F, Hosoi T, Nakamura T, Orimo H. Characteristics of steroid hormone receptors in cultured LC3T3-E1 osteoblastic cells and effect of steroid hormones on cell proliferation. Calcif Tissue Int 1992;51:376-81
    • (1992) Calcif Tissue Int , vol.51 , pp. 376-381
    • Masuyama, A.1    Ouchi, Y.2    Sato, F.3    Hosoi, T.4    Nakamura, T.5    Orimo, H.6
  • 7
    • 0023909432 scopus 로고
    • Evidence of estrogen receptors in normal human osteoblast-like cells
    • Eriksen E, Colvard D, Berg N, Graham M, Mann K, Spelsberg T, et al. Evidence of estrogen receptors in normal human osteoblast-like cells. Science 1988;241:84-6
    • (1988) Science , vol.241 , pp. 84-86
    • Eriksen, E.1    Colvard, D.2    Berg, N.3    Graham, M.4    Mann, K.5    Spelsberg, T.6
  • 12
    • 0026567181 scopus 로고
    • Interaction of androgen and 1,25-dihydroxyvitamin D3: Effects on normal rat bone cells
    • Gray C, Colston K, MacKay A, Taylor L, Arnett T. Interaction of androgen and 1,25-dihydroxyvitamin D3: effects on normal rat bone cells. J Bone Miner Res 1989;7:41-6
    • (1989) J Bone Miner Res , vol.7 , pp. 41-46
    • Gray, C.1    Colston, K.2    MacKay, A.3    Taylor, L.4    Arnett, T.5
  • 13
    • 0027407603 scopus 로고
    • Sex-specific response of bone cells to gonadal steroids: Modulation in perinatally androgenized females and in testicular feminized male rats
    • Weisman Y, Cassorla F, Malozowski S, Krieg R, Goldray D, Kaye A, et al. Sex-specific response of bone cells to gonadal steroids: modulation in perinatally androgenized females and in testicular feminized male rats. Steroids 1993;58:126-33
    • (1993) Steroids , vol.58 , pp. 126-133
    • Weisman, Y.1    Cassorla, F.2    Malozowski, S.3    Krieg, R.4    Goldray, D.5    Kaye, A.6
  • 15
    • 0006176115 scopus 로고
    • Demonstration of androgen receptors in bone marrow stromal cells and their role in the regulation of transcription from the human interleukin-6 (IL-6) gene promotor
    • Bellido T, Girasole G, Jilka R, Crabb D, Manolagas S. Demonstration of androgen receptors in bone marrow stromal cells and their role in the regulation of transcription from the human interleukin-6 (IL-6) gene promotor. J Bone Miner Res 1993;8 (Suppl 1):57
    • (1993) J Bone Miner Res , vol.8 , Issue.1 SUPPL. , pp. 57
    • Bellido, T.1    Girasole, G.2    Jilka, R.3    Crabb, D.4    Manolagas, S.5
  • 16
    • 9844222614 scopus 로고
    • Downregulation of osteoclastogenic potential in vivo by combined ac/dc magnetic fields
    • Ryaby J, Magee F, Khin N, Fitzsimmons R, Baylink D. Downregulation of osteoclastogenic potential in vivo by combined ac/dc magnetic fields. J Bone Miner Res 1993;8(Suppl 1):626
    • (1993) J Bone Miner Res , vol.8 , Issue.1 SUPPL. , pp. 626
    • Ryaby, J.1    Magee, F.2    Khin, N.3    Fitzsimmons, R.4    Baylink, D.5
  • 17
    • 0026516415 scopus 로고
    • Estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro. A potential mechanism for the antiosteoporotic effect of estrogens
    • Girasole G, Jilka R, Passeri G, Scott B, Boder G, Williams D, et al. Estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro. A potential mechanism for the antiosteoporotic effect of estrogens. J Clin Invest 1992;89:883-91
    • (1992) J Clin Invest , vol.89 , pp. 883-891
    • Girasole, G.1    Jilka, R.2    Passeri, G.3    Scott, B.4    Boder, G.5    Williams, D.6
  • 18
    • 0025147679 scopus 로고
    • Effects of androgens on parathyroid and interleukin-I-stimulated prostaglandin production in cultured neonatal mouse calvariae
    • Pilbeam C, Raisz L. Effects of androgens on parathyroid and interleukin-I-stimulated prostaglandin production in cultured neonatal mouse calvariae. J Bone Miner Res 1990;5:1183-8
    • (1990) J Bone Miner Res , vol.5 , pp. 1183-1188
    • Pilbeam, C.1    Raisz, L.2
  • 19
    • 0024448387 scopus 로고
    • Direct modulation by androgens of the response of human bone cells (SaOS-2) to human parathyroid hormone (PTH) and PTRrp
    • Fukayama S, Tashjan A. Direct modulation by androgens of the response of human bone cells (SaOS-2) to human parathyroid hormone (PTH) and PTRrp. Endocrinology 1989;125:1789-94
    • (1989) Endocrinology , vol.125 , pp. 1789-1794
    • Fukayama, S.1    Tashjan, A.2
  • 20
    • 0029928698 scopus 로고    scopus 로고
    • Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence
    • Jilka R, Weinstein R, Takahashi K, Parfitt A, Manolagas S. Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence. J Clin Invest 1996;97: 1732-40
    • (1996) J Clin Invest , vol.97 , pp. 1732-1740
    • Jilka, R.1    Weinstein, R.2    Takahashi, K.3    Parfitt, A.4    Manolagas, S.5
  • 21
    • 0030802506 scopus 로고    scopus 로고
    • The effects of androgen deficiency on murine bone remodeling and bone mineral density are mediated via cells of the osteoblastic lineage
    • Weinstein R, Jilka R, Parfitt A, Manolagas S. The effects of androgen deficiency on murine bone remodeling and bone mineral density are mediated via cells of the osteoblastic lineage. Endocrinology 1997;138:4013-22
    • (1997) Endocrinology , vol.138 , pp. 4013-4022
    • Weinstein, R.1    Jilka, R.2    Parfitt, A.3    Manolagas, S.4
  • 23
    • 0025884279 scopus 로고
    • Androgen treatment prevents loss of cancellous bone in the orchidectomized rat
    • Wakley G, Schritte H, Kathleen S, Turner R. Androgen treatment prevents loss of cancellous bone in the orchidectomized rat. J Bone Miner Res 1991;6:325-30
    • (1991) J Bone Miner Res , vol.6 , pp. 325-330
    • Wakley, G.1    Schritte, H.2    Kathleen, S.3    Turner, R.4
  • 24
    • 0014468721 scopus 로고
    • Changes in skeletal mass and fragility with castration in the rat: A model for osteoporosis
    • Saville P. Changes in skeletal mass and fragility with castration in the rat: a model for osteoporosis. Am Geriatr Soc 1969;17:155-66
    • (1969) Am Geriatr Soc , vol.17 , pp. 155-166
    • Saville, P.1
  • 25
    • 0024416113 scopus 로고
    • Comparison of the anabolic effects of synthetic parathyroid hormone-related protein (PTHrp)-34 and PTHI-34 on bone in rats
    • Hock J, Fonseca J, Gunness-Hey, Kemp B, Martin T. Comparison of the anabolic effects of synthetic parathyroid hormone-related protein (PTHrp)-34 and PTHI-34 on bone in rats. Endocrinology 1989;125:2022-7
    • (1989) Endocrinology , vol.125 , pp. 2022-2027
    • Hock, J.1    Fonseca, J.2    Gunness-Hey3    Kemp, B.4    Martin, T.5
  • 26
    • 0024404114 scopus 로고
    • Differential effects of gonadal function on bone histomorphometry in male and female rats
    • Turner R, Hannon K, Demers L, Buchanan J, Bell N. Differential effects of gonadal function on bone histomorphometry in male and female rats. J Bone Miner Res 1989;4:557-63
    • (1989) J Bone Miner Res , vol.4 , pp. 557-563
    • Turner, R.1    Hannon, K.2    Demers, L.3    Buchanan, J.4    Bell, N.5
  • 27
    • 0025457129 scopus 로고
    • Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats
    • Turner R, Wakley G, Hannon K. Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats. J Orthop Res 1990;8:612-17
    • (1990) J Orthop Res , vol.8 , pp. 612-617
    • Turner, R.1    Wakley, G.2    Hannon, K.3
  • 28
    • 0026750195 scopus 로고
    • Bone and mineral metabolism in aged male rats: Short- and long-term effects of androgen deficiency
    • Vanderschueren D, Van Herck E, Suiker A, Visser W, Schot L, Bouillon R. Bone and mineral metabolism in aged male rats: short- and long-term effects of androgen deficiency. Endocrinology 1992;130: 2906-16
    • (1992) Endocrinology , vol.130 , pp. 2906-2916
    • Vanderschueren, D.1    Van Herck, E.2    Suiker, A.3    Visser, W.4    Schot, L.5    Bouillon, R.6
  • 29
    • 0019247167 scopus 로고
    • Effects of castration on the bone structure of male rats: A model for osteoporosis
    • Wink C, Felts W. Effects of castration on the bone structure of male rats: a model for osteoporosis. Calcif Tissue Int 1980;32:77-82
    • (1980) Calcif Tissue Int , vol.32 , pp. 77-82
    • Wink, C.1    Felts, W.2
  • 31
    • 0026549647 scopus 로고
    • Long-term effect of orchidectomy on cortical bone from rat femur bone mass and mechanical properties
    • Danielson C, Mosekilde L, Andreassen T. Long-term effect of orchidectomy on cortical bone from rat femur bone mass and mechanical properties. Calcif Tissue Int 1992;50:169-74
    • (1992) Calcif Tissue Int , vol.50 , pp. 169-174
    • Danielson, C.1    Mosekilde, L.2    Andreassen, T.3
  • 32
    • 0022461659 scopus 로고
    • A scanning electronic-microscopic study of femoral bone surfaces from castrate rats treated with dichloromethylene biphosphonate
    • Wink C. A scanning electronic-microscopic study of femoral bone surfaces from castrate rats treated with dichloromethylene biphosphonate. Acta Anat 1986;126:57-62
    • (1986) Acta Anat , vol.126 , pp. 57-62
    • Wink, C.1
  • 33
    • 0027427126 scopus 로고
    • The aged male rat as a model for human osteoporosis: Evaluation by nondestructive measurements and biomechanical testing
    • Vanderschueren D, Van Herck E, Schot L, Rush E, Einhorn T, Geusens P, et al. The aged male rat as a model for human osteoporosis: evaluation by nondestructive measurements and biomechanical testing. Calcif Tissue Int 1993;53:342-7
    • (1993) Calcif Tissue Int , vol.53 , pp. 342-347
    • Vanderschueren, D.1    Van Herck, E.2    Schot, L.3    Rush, E.4    Einhorn, T.5    Geusens, P.6
  • 34
    • 0018714281 scopus 로고
    • Effects of calcium deprivation and orchidectomy on bone composition in the rat
    • Hodgkinson A. Effects of calcium deprivation and orchidectomy on bone composition in the rat. Horm Metab Res 1979;11:516-19
    • (1979) Horm Metab Res , vol.11 , pp. 516-519
    • Hodgkinson, A.1
  • 36
    • 0027273798 scopus 로고
    • A comparison of microanatomic basis for coupling between bone formation and bone resorption in man and the rat
    • Chow J, Badve S, Chambers T. A comparison of microanatomic basis for coupling between bone formation and bone resorption in man and the rat. Bone 1993;14:355-60B
    • (1993) Bone , vol.14
    • Chow, J.1    Badve, S.2    Chambers, T.3
  • 37
    • 0030958817 scopus 로고    scopus 로고
    • Aromatase inhibition impairs skeletal modeling and decreases bone mineral density in growing male rats
    • Vanderschueren D, Van Herck E, Nijs J, Ederveen A, De Coster R, Bouillon R. Aromatase inhibition impairs skeletal modeling and decreases bone mineral density in growing male rats. Endocrinology 1997;138:2301-7
    • (1997) Endocrinology , vol.138 , pp. 2301-2307
    • Vanderschueren, D.1    Van Herck, E.2    Nijs, J.3    Ederveen, A.4    De Coster, R.5    Bouillon, R.6
  • 38
    • 0021189787 scopus 로고
    • Evaluation of the pathogenesis of skeletal changes in ovariectomized rats
    • Kalu D, Hardin R, Cockerman R. Evaluation of the pathogenesis of skeletal changes in ovariectomized rats. Endocrinology 1984;115:507-12
    • (1984) Endocrinology , vol.115 , pp. 507-512
    • Kalu, D.1    Hardin, R.2    Cockerman, R.3
  • 39
    • 0028931556 scopus 로고
    • Osteoporosis in men
    • Orwoll E, Klein R. Osteoporosis in men. Endocr Rec 1995;16:87-116
    • (1995) Endocr Rec , vol.16 , pp. 87-116
    • Orwoll, E.1    Klein, R.2
  • 40
    • 0025884064 scopus 로고
    • Age, disease, and changing sex hormone levels in middle-aged men: Results of the Massachusetts male aging study
    • Gray A, Feldman H, McKinlay J, Longcope C. Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts male aging study. J Clin Endocrinol Metab 1991;73: 1016-25
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 1016-1025
    • Gray, A.1    Feldman, H.2    McKinlay, J.3    Longcope, C.4
  • 41
    • 0027249894 scopus 로고
    • Low circulating levels of insulin-like growth factors and testosterone in chronically institutionalized elderly men
    • Abassi A, Drinka P, Mattson D, Rudman D. Low circulating levels of insulin-like growth factors and testosterone in chronically institutionalized elderly men. J Am Geriatr Soc 1993;41:975-82
    • (1993) J Am Geriatr Soc , vol.41 , pp. 975-982
    • Abassi, A.1    Drinka, P.2    Mattson, D.3    Rudman, D.4
  • 42
  • 43
  • 45
    • 0024509604 scopus 로고
    • Importance of gonadal steroids to bone mass in men with hyperprolactinemic hypogonadism
    • Greenspan S, Oppenheim S, Klibanski A. Importance of gonadal steroids to bone mass in men with hyperprolactinemic hypogonadism. Ann Intern Med 1989;110:526-31
    • (1989) Ann Intern Med , vol.110 , pp. 526-531
    • Greenspan, S.1    Oppenheim, S.2    Klibanski, A.3
  • 46
    • 0030807921 scopus 로고    scopus 로고
    • Age-associated endocrine deficiencies as potential determinants of femoral neck (type II) osteoporotic fracture occurrence in elderly men
    • Boonen S, Vanderschueren D, Geusens P, Bouillon R. Age-associated endocrine deficiencies as potential determinants of femoral neck (type II) osteoporotic fracture occurrence in elderly men. Int J Androl 1997;20:134-43
    • (1997) Int J Androl , vol.20 , pp. 134-143
    • Boonen, S.1    Vanderschueren, D.2    Geusens, P.3    Bouillon, R.4
  • 47
    • 0030685090 scopus 로고    scopus 로고
    • Endogenous sex steroids and bone mineral density in older women and men: The Rancho Bernardo Study
    • Greendale G, Edelstein S, Barrett-Connor E. Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo Study. J Bone Miner Res 1997;12:1833-43
    • (1997) J Bone Miner Res , vol.12 , pp. 1833-1843
    • Greendale, G.1    Edelstein, S.2    Barrett-Connor, E.3
  • 48
    • 0026446492 scopus 로고
    • Hip fractures in the elderly: A world-wide projection
    • Cooper C, Campion G, Melton L. Hip fractures in the elderly: a world-wide projection. Osteoporosis Int 1992;2:285-9
    • (1992) Osteoporosis Int , vol.2 , pp. 285-289
    • Cooper, C.1    Campion, G.2    Melton, L.3
  • 50
    • 0026342804 scopus 로고
    • Does hypogonadism contribute to the occurrence of a minimal trauma hip fracture in elderly men?
    • Stanley HL, Schmitt BP, Poses RM, Deiss WP. Does hypogonadism contribute to the occurrence of a minimal trauma hip fracture in elderly men? J Am Geriatr Soc 1991;39:766-71
    • (1991) J Am Geriatr Soc , vol.39 , pp. 766-771
    • Stanley, H.L.1    Schmitt, B.P.2    Poses, R.M.3    Deiss, W.P.4
  • 51
    • 0026750846 scopus 로고
    • Testosterone deficiency as a risk factor for hip fractures in men: A case-control study
    • Jackson J, Riggs M, Spiekerman A. Testosterone deficiency as a risk factor for hip fractures in men: a case-control study. Am J Med Sci 1992;304:4-8
    • (1992) Am J Med Sci , vol.304 , pp. 4-8
    • Jackson, J.1    Riggs, M.2    Spiekerman, A.3
  • 52
    • 0030734811 scopus 로고    scopus 로고
    • Age-related (type II) femoral neck osteoporosis in men: Biochemical evidence for both hypovitaminosis D- and androgen deficiency-induced bone resorption
    • Boonen S, Vanderschueren D, Cheng X, Verbeke G, Dequeker J, Geusens P, et al. Age-related (type II) femoral neck osteoporosis in men: biochemical evidence for both hypovitaminosis D- and androgen deficiency-induced bone resorption. J Bone Miner Res 1997;12:2119-26
    • (1997) J Bone Miner Res , vol.12 , pp. 2119-2126
    • Boonen, S.1    Vanderschueren, D.2    Cheng, X.3    Verbeke, G.4    Dequeker, J.5    Geusens, P.6
  • 53
    • 0026078286 scopus 로고
    • Effects of testosterone and venesection on spinal and peripheral bone mineral in six hypogonadal men with hemochromatosis
    • Diamond T, Stiel D, Posen S. Effects of testosterone and venesection on spinal and peripheral bone mineral in six hypogonadal men with hemochromatosis. J Done Miner Res 1991;6:39-43
    • (1991) J Done Miner Res , vol.6 , pp. 39-43
    • Diamond, T.1    Stiel, D.2    Posen, S.3
  • 56
    • 10244222400 scopus 로고    scopus 로고
    • Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men - A clinical research center study
    • Wang C, Eyre DR, Clark R, Kleinberg D, Newman C, Iranmanesh A, et al. Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men - a clinical research center study. J Clin Endocrinol Metab 1996;81:3654-62
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3654-3662
    • Wang, C.1    Eyre, D.R.2    Clark, R.3    Kleinberg, D.4    Newman, C.5    Iranmanesh, A.6
  • 59
    • 0026742650 scopus 로고
    • Effects of testosterone supplementation in the aging male
    • Tenover J. Effects of testosterone supplementation in the aging male. J Clin Endocrinol Metab 1992;75: 1092-8
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1092-1098
    • Tenover, J.1


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