Preparations of 1-hydroxyindole derivatives and their potent inhibitory activities on platelet aggregation

Heterocycles

Volumn 43, Issue 9, 1996, Pages 1855-1858

  Somei, Masanori ^a   Yamada, Koji ^a   Hasegawa, Masakazu ^a   Tabata, Mutsuko ^a   Nagahama, Yoshiyuki ^a   Morikawa, Harunobu ^a   Yamada, Fumio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0001471643     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-96-7537     Document Type: Article

References (14)

1. This is Part 78 of a series entitled "The Chemistry of Indoles". Part 77: M. Somei, H. Hayashi, and S. Ohmoto, Heterocycles, 1997, 44, (No. 1), in press. All new compounds gave satisfactory spectral data and elemental analyses for crystals or high resolution mass spectral data for oils. 3a) oil; 3b) oil; 3c) oil; 4a) oil;4b) mp 111.5-113.0°C;4c) mp 117.5-118.5°C; 9a) mp 260°C (decomp.); 9b) mp 261°C (decomp.); 10) mp 171°C (sharp); 12) mp 132-133°C; 13) mp 194-200°C (decomp.); 15) oil; 16) mp 114.5-115.0°C; 19) mp 179-180°C; 20) mp 181-183°C (decomp.).
2. a) M. Somei and T. Kawasaki, Heterocycles, 1989, 29, 1251;
3. b) Review: M. Somei, Yuki Gosei Kagaku Kyokai Shi, 1991, 49, 205;
4. c) M. Somei, K. Kobayashi, K. Tanii, T. Mochizuki, Y. Kawada, and Y. Fukui, Heterocycles, 1995, 40, 119 and references reported before 1995 are cited therein.
5. W. Pierpaoli, Aging, 1991, 3, 99; H. Schmid, Gerontology, 1993, 39, 189; S. -W. Ying, L. P. Niles, and C. Crocker, Eur. J. Pharmacol., Mol. Pharmacol. Sect, 1993, 246, 89; F. Waldhauser, B. Ehrart, and E. Forster, Experientia, 1993, 49, 671.
6. W. Pierpaoli, Aging, 1991, 3, 99; H. Schmid, Gerontology, 1993, 39, 189; S. -W. Ying, L. P. Niles, and C. Crocker, Eur. J. Pharmacol., Mol. Pharmacol. Sect, 1993, 246, 89; F. Waldhauser, B. Ehrart, and E. Forster, Experientia, 1993, 49, 671.
7. W. Pierpaoli, Aging, 1991, 3, 99; H. Schmid, Gerontology, 1993, 39, 189; S. -W. Ying, L. P. Niles, and C. Crocker, Eur. J. Pharmacol., Mol. Pharmacol. Sect, 1993, 246, 89; F. Waldhauser, B. Ehrart, and E. Forster, Experientia, 1993, 49, 671.
8. W. Pierpaoli, Aging, 1991, 3, 99; H. Schmid, Gerontology, 1993, 39, 189; S. -W. Ying, L. P. Niles, and C. Crocker, Eur. J. Pharmacol., Mol. Pharmacol. Sect, 1993, 246, 89; F. Waldhauser, B. Ehrart, and E. Forster, Experientia, 1993, 49, 671.
9. M. Somei and Y. Fukui, Heterocycles, 1993, 36, 1859.
10. S. Hamabuchi, H. Hamada, A. Hironaka, and M. Somei, Heterocycles, 1991, 32, 443.
11. M. Somei, E. Iwasa, and F. Yamada, Heterocycles, 1986, 24, 3065.
12. F. Yamada, S. Hamabuchi, A. Shimizu, and M. Somei, Heterocycles, 1995, 41, 1905 and references cited therein.
13. M. Somei, M. Hasegawa, H. Morikawa, R. Yamagami, and T. Ochi, Abstracts of Papers 2, The 116th Annual Meeting of Pharmaceutical Society of Japan, Kanazawa, March 1996, p. 252.
14. Leading reference: M. Somei, Y. Fukui, and M. Hasegawa, Heterocycles, 1995, 41, 2157 and references cited therein.